Biomedical subjects
M Yazaki
Publications and source records attributed to M Yazaki.
Copper-binding proteins in the liver and kidney from the patients with Menkes' kinky hair disease.
Copper-binding proteins in the tissues from the patients with Menkes' kinky hair disease were examined by gel filtration on a Sephadex G-75 column. In the kidney, major part of copper was found to bind to low molecular weight protein, which corresponded chromatographically to metallothionein. This copper-binding protein contained a large amount of copper and a small amount of zinc. Cu: Zn ratio of this protein was different from that of metallothionein found in the fetal liver. In the liver of the same patient, however, there was no increase of copper bound to this protein.
[Irritant properties of four root canal filling materials].
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[Study on handling of broken instruments in root canal. Study on distribution of metal in the teeth treated by iontophoresis with transparent specimens (author's transl)].
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Gmi-gangliosidosis. A variant with high activity of hepatic neutral beta-galactosidase.
A case of GM1-gangliosidosis with high activity of hepatic neutral beta-galactosidase is reported. GM1-beta-galactosidase was deficient. Ganglioside GM1 was accumulated in the liver of this patient. Clinically this Japanese girl started convulsive seizures at 5 months of age, had hepatomegaly, and macular cherry-red spots, but lacked gargoylelike clinical characteristics. Correlation of clinical and biochemical data is discussed.
[Bacteriological relapse among the previously treated advanced pulmonary tuberculosis patients whose sputum converted to negative by the rifampicin treatment, with special reference to the duration of rifampicin administration (author's transl)].
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[Neuropathological studies on neuro-Behçet's syndrome].
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[Continuous and prolonged symptoms in 2 cases of gas poisoning].
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[2 cases of acute disseminated encephalomyelitis].
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[Therapeutic effects of four drug-combination therapy for previously untreated tuberculosis patients].
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Correlation of regional cerebral blood flow with performance on neuropsychological tests in schizophrenic patients.
Regional cerebral blood flow (rCBF) was determined by the 133Xe inhalation technique (Headtome II: ring detection SPECT) in 53 DSM-III schizophrenic patients. The rCBF values were corrected by using end-tidal carbon dioxide concentration values (PECO2). After rCBF measurement, neuropsychological tests--Word Fluency Test, Maze Test and Wisconsin Card Sorting Test--were performed. There were significant correlations between frontal rCBF and scores on each neuropsychological test. In particular, a moderate correlations between the frontal rCBF and the performance on the Wisconsin Card Sorting Test was noted. It seems likely that decrease of rCBF in prefrontal regions at rest reflects a disturbance of frontal lobe function in schizophrenic patients.