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Biomedical subjects

M Yeo

Publications and source records attributed to M Yeo.

9 recordsLinked to original sources

Serodiagnosis of melioidosis in Singapore by the indirect haemagglutination test.

Melioidosis is endemic in Singapore, with diagnosis dependent upon both bacteriological culture and serodiagnosis. Using the polysaccharide (melioidin)-sensitized turkey red cells in the indirect haemagglutination test (IHAT), 20 (100%) of the Pseudomonas pseudomallei culture-positive cases were detectable by the IHAT with titles ranging from 1:16 to 1:32, 768. Eight of these patients who died within a few days after the IHAT was performed had titres ranging from 1:16 to 1:1028. Five culture-negative patients, with clinical symptoms suggestive of melioidosis infection and who responded to treatment with ceftazidime, showed IHA titres between 1:64 and 1:8,192. One hundred and twenty one sera from patients with pneumonia, abscesses, or diabetes mellitus were IHAT negative. The IHAT showed good specificity since negative titres were seen in tests using sera from 2 patients with culture-positive Pseudomonas aeruginosa and 4 patients positive for Legionella. IHAT negative results were obtained from tests of 50 normal blood donors and 50 sewerage workers. Of 683 national servicemen tested, 5 (0.73%) had IHAT titres ranging from 1:16 to 1:128. Unlike hyperendemic areas such as Thailand where interpretation of IHAT is seriously hampered by IHA titres found in one-third to half of the population, serodiagnosis of melioidosis by the sensitive IHAT may be employed in Singapore as a routine procedure since background IHA titres are low.

Hemagglutination Tests

Integration of nursing theory and nursing ethics.

Nursing theory and nursing ethics are the two main areas of inquiry in nursing scholarship today. Each addresses common themes and each, in its own way, speaks not only about but for nursing. In spite of this commonality there is remarkably little dialogue between them. Both theory and ethics shall benefit from increased integration.

Ethics, Nursing

The impact of preventive cardiology on coronary artery disease.

Ischemic heart disease continues to be the leading cause of death among middle-aged people in industrialized countries. However, in North America the rates of death and disability from coronary artery disease (CAD) have declined, mostly because of a reduction of the main modifiable risk factors (high serum cholesterol levels, smoking and hypertension). Intervention trials have consistently shown that the lowering of the severity of risk factors decreases the incidence of CAD. These studies have introduced the goals of preventive cardiology to clinicians but have not provided the necessary knowledge and skills to achieve them. Unfortunately, with the exception of hypertension, the risk factors for CAD are infrequently assessed and managed in ambulatory patients. Incorporation of detection and intervention strategies derived from recent epidemiologic, behavioural and biomedical research into the existing primary health care system may be the most efficient and effective approach to further reducing the impact of CAD. The family physician's office is the ideal location to implement behavioural change strategies. However, primary care intervention to decrease the risk of ischemic heart disease among people at high risk has yet to be studied. In addition, whether the same clinicians who render primary care can assume the responsibility for surveillance and preventive care has to be demonstrated.

Antihypertensive Agents

Fosfomycin.

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Fosfomycin

Blood pressure screening clinics: an opportunity for health promotion.

A blood pressure clinic was organized in a newly developed community in an urban setting. While the primary purpose was to measure and interpret blood pressure (BP), special emphasis was placed on creating awareness of normal/abnormal BP. The study was also designed to identify health education activities performed by nurses in a BP clinic. Following an orientation program and using standardized protocol, volunteer nurses screened 671 adults with a mean age of 43.7 years. The additional activities performed by nurses are described and include 72 documented instances of health teaching, 111 referrals for elevated BP, and 32 referrals for other health problems. The results indicate that nurses provided valuable services in meeting consumer health care needs, and suggest that a BP clinic can be an effective and efficient vehicle for health promotion activities.

Adult

Pharyngitis 1987: a survey of physicians' attitudes and practices in southern Alberta.

A questionnaire survey concerning Streptococcal pharyngitis was completed by 85 southern Alberta family physicians. The data revealed a significant trend to overtreat pharyngitis with antibiotics because of the unreliability of clinical diagnosis and the lack of diagnostic manoeuvres with suitable ability to influence management. These data and a further questionnaire survey directed to the appreciation of other bacterial pharyngitides, demonstrate the importance of laboratory reports in biasing treatment, and further suggest that significant overtreatment of non-Streptococcal pharyngitis also occurs.

Alberta