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Biomedical subjects

M Z Kenawi

Publications and source records attributed to M Z Kenawi.

4 recordsLinked to original sources

Treatment of human scabies by sulfur and permethrin.

Scabies is one of the most important prevalent contagious disease caused by itch mite "Sarcoptes scabiei." Many effective scabiecides have been suggested and tried. They differ in their side effects since they are applied on diseased skin sometimes all over the body. In this paper, sixteen parasitologically proved human scabies were successfully treated by 5% sulfur precipitate and 2.5% permethrin. Application of sulfur for one week or 2 applications of permethrin followed by a third one a week later proved to be safe and effective. The one week course of sulfur and the third application of permethrin acts against any emerging immature stages of the mite.

Follow-Up Studies↗

Serum immunoglobulin and complement values in scabietic patients.

Immunity entails all the forces concerned with recognition, specific reaction and removal of foreign bodies after they again access into the body of the host. The immune system interacts with genetics and infectious agents as well as with metabolic, endocrine and environmental factors. The serum immunoglobulins (G.M.A. & E.) and complement (C3 and C4) were estimated in sixteen parasitologically proven patients with scabies. The causative agent was Sarcoptes scabiei. The results showed a high significant increase in the mean average of IgG., IgM. and in particular IgE pretreatment than in patients three months after treatment and in patients after treatment than in controls. On the other hand, there was a significant decrease in the mean average in the mean average of IgA after treatment was insignificant compared with controls. The C3 and C4 showed no significant changes in the mean average in the patients before or after treatment compared with controls. The changes in the IgG., IgM. and in particular IgE. may be specific reaction to the parasite or a non specific one to the dead parasite or its faeces or even to a secondary infection developed. On the other hand, the decrease in the IgA. may be due to the mite or its products which interfere with its synthesis. It is concluded that scabies is associated with a humoral immunological response against the mite infestation.

Animals↗

Clinical and parasitological aspects on human scabies in Qualyobia Governorate, Egypt.

In the last decade, human scabies caused by Sarcoptes scabiei and other non human strains is one of the most common contagious parasitic disease. Over a period of one year (June 1991--May 1992), a total of 200 scabietic patients were diagnosed in the outpatients' clinic of Dermatology and Venereology, Benha University Hospitals. They were 120 females and 80 males (sex ratio = 1.5:1). Their ages ranged between three months up to 70 years old. Most of the patients were parasitologically positive (160 or 80%). The most common signs and symptoms were itching, skin burrows, scratch markings, papules and pustules. Regional lymphadenitis was sometimes present as well as fever in patients with secondary bacterial infection. The most affected sites were the abdomen (100%), followed by the buttocks (81.3%), the thigh (50%), legs (50%) and the arms and web spaces (62.5%). The male external genitalia was infested in 60% and the female breast was infested in 72.7%. The sex and site distribution of the infestations were attributed to the risk factor of exposure to infestation. The patients were successfully treated with 5% sulfur precipitate and 2-5% permethrin. The whole results were discussed on the light of the previous work.

Adolescent↗

Two indigenous cases of cutaneous leishmaniasis in Qualyobia Governorate, Egypt.

This paper reports two indigenous cases of cutaneous leishmaniasis for the first time in Kafr Shokr, Qualyobia Governorate. One of the two cases was misdiagnosed as cutaneous tuberculosis (primary complex) and was kept on TB treatment, but with no clinical improvement. The two patients were successfully treated with sodium stibogluconate (pentostam).

Adult↗