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Biomedical subjects

M Z Marder

Publications and source records attributed to M Z Marder.

11 recordsLinked to original sources
PubMed2000

Squamous cell carcinoma in an American bison (Bison bison bison).

The following case report is, to the best of our knowledge, the first documentation of a squamous cell carcinoma in a full-blooded American bison (Bison bison bison). This female bison developed an ulcerated lesion on the left flank, at the site of a brand, in the summer of her eighth year. In the winter of her ninth year, as the lesion continued to grow, a biopsy was performed, and a diagnosis of squamous cell carcinoma was made. Ultimately, there was metastasis to the liver, a lung, and a prefemoral lymph node.

Animals↗
PubMed1998

The standard of care for oral diagnosis as it relates to oral cancer.

The periodic oral examination of patients must be performed by the dentist as standard procedure. As a physician of the mouth, the dentist must also be able to recognize abnormalities or lesions and then provide, or refer patients for, diagnosis, treatment, and surveillance of the condition. With prompt and decisive action, the dentist can save lives and influence the morbidity of oral cancer. Conversely, inadequate diagnostic skills and improper documentation techniques can incur legal consequences.

Adult↗
PubMed1985

Cytomegalovirus presence and salivary composition in acquired immunodeficiency syndrome.

Parotid and whole saliva was collected from nine patients with acquired immunodeficiency syndrome (AIDS) and nine controls. Cytomegalovirus (CMV) was cultured from both salivary samples in six of the AIDS patients but was not present in any of the controls. In the AIDS samples parotid sodium (p less than 0.05), IgG (p less than 0.01), and albumin (p less than 0.05) were higher than in control samples. Parotid potassium (p less than 0.05) and total protein (p less than 0.05) were lower than control values, whereas flow rate, lactoferrin, lysozyme, IgA, and IgM levels were similar in both sets of samples. AIDS does not appear to affect secretory IgA levels. Sodium (p less than 0.01) and IgA (p less than 0.05) were higher in the whole saliva of AIDS patients. Serum IgG, IgM (p less than 0.01), and IgA (p less than 0.05) were also elevated when compared with the controls. The prevalence of CMV in parotid and whole saliva of AIDS patients is consistent with the known susceptibility of this group to adventitious infection and the predilection of this virus for the salivary glands. The changes in salivary composition suggest a low level of inflammation, which occurs independently of the virus.

Acquired Immunodeficiency Syndrome↗
PubMed1982

Transformation of oral lichen planus to squamous cell carcinoma: a literature review and report of case.

We have presented a case of malignant transformation of oral lichen planus along with a review of the literature and a brief description of the disease. We have attempted to indicate that within defined terms, oral lichen planus should be considered a pre-malignant lesion in which incidence of transformation approaches that of clinical oral leukoplakia, yet is clearly distinctive from that disease with regard to age and sex distribution. The erosive form of oral lichen planus most often precedes carcinomatous change. A protocol is described for documentation and periodic follow-up procedures for such patients to possibly intercept a developing malignancy.

Aged↗
PubMed1975

Salivary alterations in diabetes mellitus.

Separately collected parotid and submaxillary salivary samples from 20 diabetic and 20 matched control subjects were analyzed for flow rate, electrolyte content and immunoglobulin (IgA, IgG and IgM) levels. Flow rates did not vary significantly between the two groups of subjects; calcium ion content, however, was higher in the diabetic subjects for both salivary glands. The presence of salivary IgI in 6 of 10 patients was also a significant finding. Any attempt to draw a conclusion between the severity of periodontal disease and Diabetes Mellitus from the above findings is still speculative but does indicate further areas of research.

Adult↗