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M Załuska

Publications and source records attributed to M Załuska.

25 records · Page 2Linked to original sources
PubMedDate not supplied

[Agranulocytosis in the course of clozapine treatment].

Clozapine is highly effective for drug resistant schizophrenia, it does not cause any extrapiramidal side effects, but involves a high risk of agranulocytosis with fatal outcome. The pathogenesis of agranulocytosis is not clear but genetic factors, as well as immunological and toxic mechanism may play an important role. Since the introduction of the monitoring system of leucocytosis for every patient an increasing number of agranulocytosis cases are being registered. Owing to the monitoring system, an immediate discontinuation of the drug, and the initiation of appropriate treatment the number of cases with fatal outcome is not growing in spite of the increasing number of patients treated with clozapine. In the described patient with chronic schizophrenia and ulcerative disease, agranulocytosis disappeared within 7 days after discontinuation of the drug. Three months later the patient died because of perforation of a duodenal ulcer. A negative influence of closapine on ulcerative disease should by considered, but the authors have not found any information on this topic in the literature.

Agranulocytosis↗
PubMedDate not supplied

[Methods of measurement of social adjustment in schizophrenia].

Social functioning as well as reduction of psychopathological symptoms constitute basic criteria for evaluation of effectiveness of psychiatric treatment and rehabilitation. Social functioning is often estimated by measuring fulfillment of social roles as well as concurrent difficulties and behaviour of patients who can be troublesome to others-RASP, and SRPS scales (9, 20). KAS and SAS Scales (11, 21) focused on measuring social "adjustment" itself are being criticized. The LSP, SFS, ILLS (4, 15, 24) can be recognized as scales that are easy to use and adopted to the specific functioning of schizophrenics. These scales measure basic abilities needed for independent life outside mental hospital. They are being used for planning social rehabilitation and community care.

Humans↗
PubMedDate not supplied

[Social functioning of schizophrenic patients after 15 years from the first hospitalization (Part I -- evaluation of social functioning)].

Catamnestic data concerning 109 patients, inhabitants of Warsaw-Praga, hospitalized for the first time in the years 1978-79 with schizophrenia (92 persons) or paranoid psychosis-ICD IX number 297.9 (17 persons), were collected in 1993-94. Smaller number and shorter duration of hospitalisations has been observed during 15 years, in comparison with other Polish data. Twenty persons died during the period of observation. In the group of 85 investigated persons-69% were not working at all-15% were fully and 18% partially unable to meet their basic needs on their own-29% were temporarily or permanently unable to function adequately in their marital and/or parental roles, 31% were single and childless. Taking into account the mortality among 109 observed persons (18.7% during 15 years); good prognosis according to social functioning has been found in 48.6% of the group observed at first hospitalisation.

Adolescent↗
PubMedDate not supplied

[Social functioning of schizophrenic patients after 15 years from the first hospitalization (Part II -- the evaluation of needs for community care)].

The description of the studied group was given in the first part of the paper. Some of the factors having been present at the first hospitalization were found to be important for the patients' functioning 15 years later. On the basis of the collected regarding data 85 patients, significant coincidence has been found between more intensive use of extramural services, more frequent and longer hospitalizations, and worse social functioning during 15 years' period in individual cases. The conclusion has been assumed that there exists obvious need for more intensive community care for such patients. On the basis of 0.15% morbidity index the number of schizophrenics needing social support, sheltered accommodation and sheltered working conditions were estimated. According to the Mental Health Care Act of 1994 such services have to be organized within social care system.

Adult↗