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M Zahálková

Publications and source records attributed to M Zahálková.

At least 19 recordsLinked to original sources

[Changes in perinatal mortality in twins].

Perinatal mortality of twins born in South Moravian Region in the years 1983-1987 was compared with that observed in the years 1970-1976. The perinatal mortality of twins decreased from 119,35 per thousand to 64,21 per thousand (the corresponding numbers for the whole population of the region in question are 16.48 per thousand and 11.30 per thousand respectively). The mortality of twins shows no reasonable changes. The early neonatal mortality decreased from 98.32 per thousand to 41.23 per thousand (the corresponding numbers in the whole population are 10.25 per thousand and 6.05 per thousand respectively). As in other countries the most important cause is the decrease of prematurity. This was observed both in the evaluation according to the birth weight and according to the gestational age as well as when the main cause of death was evaluated. Nevertheless also in the second sample a higher mortality of twins B than that of twins A was observed. The results of the leading clinics in the perinatal care show no more higher mortality of twins B namely due to the decrease of the number of RDS deaths. To achieve such object will be the nearest task in our perinatal care for the twins pregnancies and neonates.

Birth Weight↗

[Growth, weight and physical proportionality in twins].

The growth, weight and proportionality of twins aged 1-15 years from the South Moravian Region were studied and compared with a control population. The sample of twins was divided in three groups: identical twins, nonidentical like-sexed twins and boys and girls from the unlike-sexed pairs. No reasonable differences between twins A and B were observed, therefore they are not evaluated separately. All the twins were born in years 1973-1987, the total number was 2,226 boys and 2,302 girls. A comparison with a control population revealed a lower mean height as well as weight of identical twins until the age of 15 years. The mean weight of identical twins was lower than that of nonidentical ones. Similar pattern were observed also in height, the statistical significance was found only in boys and only on a 5% level. Twins from unlike-sexed pairs were more like the control population than twins from unidentical like-sexed pairs, however, the differences in height in girls were not statistically significant. The distribution of proportionality values has shown an accumulation near zero--we can conclude that twins are more proportionate than other children of their age (i.e. less obese and less meagre). As expected, the observed intra-pair differences in identical pairs were significantly lower than in nonidentical like-sexed pairs.

Adolescent↗

Spontaneous abortions and twinning.

The relation between spontaneous abortions and twinning was studied in the years 1980-1981 in 22 towns of the South Moravian Region, Czechoslovakia. Each town has more than 10,000 inhabitants and less than 750 births per year. The number of spontaneous abortions and the number of twin births were evaluated separately for each town and for a time unit of three months. The comparison indicated that the group with a higher number of spontaneous abortions also had a lower number of twin births. The relation between spontaneous abortions and twinning is discussed.

Abortion, Incomplete↗

Clustering of twin births in space and time.

Out of a total of 1025 twin births occurring in 11 South Moravian districts from 1972 to 1976, 638 occurred in the same time and space interval (P = 0.00037). The observed clustering suggests the existence of environmental factors influencing twinning rates.

Czechoslovakia↗

Anti-A and anti-B isohemagglutinins in the course of children's leukemias.

The changes in titres of isohemagglutinins anti-A and anti-B were followed up in 48 leukemic children during relapses and remissions. The levels of titres were compared 1. with levels in healthy children in the same age group, 2. in the different phases of disease in the same child. Compared with healthy children, a higher frequency of low isohemagglutinin levels was found in the phases of the exacerbation of malignancy, no changes were observed in remissions. In some children a quite evident fluctuation of isohemagglutinin titres in relation to the phases of the malignant disease was found. The depression of blood group isohemagglutinins in the phases of activation of the malignant process is considered as a partial defect in IgM, analogical to the so called normoglobulinemic defect of the antibodies.

ABO Blood-Group System↗

Perinatal and infant mortality in twins.

The perinatal and infant mortality in the sample of all children born in the South Moravian Region of Czechoslovakia in the years 1970--1976 was studied. The total number of births was 237,655, including 4,072 twin children. The perinatal mortality of twins was 11 times higher and the infant mortality of twins was six times higher than those of the singletons. The mortality of B twins was significantly higher, especially in the groups with birthweight of 1,000 to 2,499 gm and with a gestational age of 22--36 weeks. The most important causes of deaths in twins are prematurity and anoxia or hypoxia. The B twin is more at risk, but also for the A twin the risk is higher for the average singleton. This difference disappears when only the infants with low birthweights are compared.

Birth Order↗

Atopy and cancer.

Malignancies were observed less frequently in the closest relatives of the patients suffering from hay fever with the most proved hereditary liability of atopy than in the relatives of control groups.

Antibodies, Neoplasm↗