PubMed Health⌕ Search

Biomedical subjects

M Zamfirescu-Gheorghiu

Publications and source records attributed to M Zamfirescu-Gheorghiu.

At least 19 recordsLinked to original sources

Screening tests for the enzymatic diagnosis in liver diseases and myocardial infarction.

To perform the ever increasing number of analyses with a minimum equipment the tendency all over the world is now to replace the classical tests with screening tests. The laboratory of enzymology of the Institute of Internal Medicine has achieved screening tests for the estimation of alkaline phosphatase, of total lactatedehydrogenase and of its fraction I, whose results are in agreement with the reference methods of Bessy-Lowry-Brock and of Lac-Dehystrate-Goedecke in cases of acute and chronic liver diseases, neoplasms, bone diseases (Paget's disease) and myocardial infarction.

Alkaline Phosphatase↗

Variations of salivary amylase as a test of internal irradiation in man.

The hypothesis of the parotid gland radiosensitivity has suggested to the authors to follow up the effect of therapeutic internal irradiation on the serum, urine and salivary alpha-amylase activity in man. The assay and visualization of alpha-amylase isoenzymes on agar gel zymograms by using the "Phadebas amylase test" tablets has demonstrated in some cases increases of salivary alpha-amylase activity expressed by the ratio of the optical density after internal irradiation to that before administration of radioisotopes.

Amylases↗

Platelet energetic enzymes.

The LDH isoenzymic pattern was studied in platelet cytolysates from man and rabbits, and the two forms of ATP-ase-the Mg++ and the Ca++ activated ones--were assayed in human platelet cytolysates. In man, the platelet LDH zymogram was of the intermediary type. Some of the zymograms presented 4 fractions others 5; in all patterns the H/M subunits ratio was above 1. In rabbits, the platelet LDH zymogram was of the anodal type with only 4 bands; the H/M subunits ratio showed the same variations as in man. Of the two forms of ATP-ase, the Mg++ activated one was dominant in the platelet cytolysates studied.

Adenosine Triphosphatases↗