Pharmacology of oxytocin-(1-6)-hexapeptide amide, vasopressin-(1-6)-hexapeptide amide and their deamino analogues.
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Amides↗
Biomedical subjects
M Zaoral
Publications and source records attributed to M Zaoral.
[Therapy of diabetes insipidus with a synthetic arginine-vasopressin analog].
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Adult↗
Peptides with juvenile hormone activity.
Peptide derivatives of juvenile hormone analogs which show substantial hormonal activity for certain insects were prepared. The most active compound, L-isoleucyl-L-alanyl-p-aminobenzoic acid ethyl ester, was up to twice as active as juvabione. Like juvabione, the peptide analog showed selective action on pyrrhocorid bugs.
Animals↗
Effect of a synthetic analogue of vasopressin in animals and in patients with diabetes insipidus.
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Adolescent↗
Tentative identification of arginine vasotocin in the bovine pineal extract prepared by in the bovine pineal extract prepared by the Milcu-Nanu method.
The bovine pineal extract prepared by the Milcu-Nanu method (BPE-MN) has frog bladder, rat antidiuretic and rat uterine activities susceptible to tryptic digestion. The ratios of these activities are characteristic of arginine vasotocin (AVT). Desalting on Amberlite CG25 and partial purification of BPE-MN by free-flow continuous electrophoresis (FFCE) allow the separation of some fractions with AVT-like biological activities and with a carrier-free electrophoretic mobility similar to the synthetic AVT. The results strongly suggest the presence of AVT in the bovine pineal extract prepared by the Milcu-Nanu method.
Animals↗