Biomedical subjects

M Zarzycka

Publications and source records attributed to M Zarzycka.

At least 19 recordsLinked to original sources

PubMed2002

[Short stature treatment by lower limb lengthening--multicenter study from five centers].

MATERIAL: 26 patients (17 female, 9 male) from 5 centers were evaluated. The age at the beginning of treatment ranged from 6 to 29 years (mean 13.8). The cause of short stature in 19 patients was achondroplasia or pseudoachondroplasia, in next 2--other bone dysplasias. The other 5 patients had not bone pathology and were treated because of cosmetic indications. Preoperative body height ranged from 90 to 149 cm (mean 120). Axial deviations of the lower extremities were noted in 11 patients. Mean follow-up was 3.7 years. METHOD OF TREATMENT: Most of patients were treated with Ilizarov device using cross lengthening strategy (2 stages--opposite femur and tibia lengthening). Mean duration of treatment including interval between two stages (mean 12 months) was 29 months. Planned increase of body height ranged from 10 to 26 cm (mean 16.4). RESULTS: Planned or greater lengthening (mean 14.8 cm) was achieved in 14 patients. Partial planned lengthening (mean 65% of planned lengthening) was achieved in 8 patients (mean 11.8 cm) including two patients who resigned the second stage of treatment. In two patients lengthening was stopped during first month of treatment because of great complications. In 2 patients treatment was not completed (interval between first and second stage). Mean increase of body height of patients with complete treatment was 13.1 cm (from 2 to 28). Problems, obstacles and complications were analyzed according to Paley classification. PROBLEMS: There were 24 problems in 15 patient (inflammation process around K wires--15 patients, bone healing disturbances--3, regenerate fracture--2, transient foot equinus--2 and axial deviation of the lower extremity--1). OBSTACLES: There were 31 obstacles in 19 patients (regenerate's defect--7 patients, premature bone consolidation--6, foot equinus--4 and other--14). COMPLICATIONS: There were 26 complications in 18 patients (axial deviation of the lengthened segment--8, foot equinus--6, paresis of the peroneal nerve--3, fractures--2 and other--5). The most serious complication was hemiparesis after cerebral embolism (1 patient) and damaging of the femoral artery (1 patient) both disrupting bone lengthening. CONCLUSION: The risk of complication in surgical treatment of short stature patients is high. Qualification for short stature treatment because of cosmetic indication should be made very careful and after precise psychological and/or psychiatric investigation.

Adolescent↗

PubMed2001

[Computer analysis of bones and regeneration on radiographs taken during limb lengthening--introductory comments].

Computer assisted image analysis is used for qualitative assessment of radiographs more and more often. The aim of this study was to define a method enabling objective assessment of changes in bone structure, using standard radiographs during limb elongation. Application of such analysis for assessment of bone and regenerate during limb elongation is described. The method of estimation of the obtained results is also presented. The obtained results encourage the authors to continue their studies, so as to make objective assessment of bone using standard radiographs a common method.

Bone Lengthening↗

PubMed1998

The value of postoperative radiotherapy in advanced renal cell cancer.

The study reviews experience with the treatment of advanced renal cell cancer at Bydgoszcz Regional Cancer Center within a 10-year period from 1985 to 1996. The aim of this paper was to evaluate the value of postoperative radiotherapy. The medical records of 186 patients with locally advanced renal cell cancer were reviewed retrospectively. Postoperative radiation therapy with a median dose of 50.0 Gy/t was given in 114 patients. The overall and disease-free survival, the pattern of recurrences, time interval to recurrence were assessed. For all patients, the 5-year overall and disease-free survival rates were 36.2% and 30.5%, respectively. Non significant difference was observed in terms of 5-year overall and disease-free survival between the group of patients with postoperative radiotherapy and without, 37.9%/29.5% vs. 35.5%/31.3%, respectively. A total of 29 patients (15.6%) developed local recurrences. Local failure by stage was as follows: T3N0 without postoperative radiation therapy--15.8%, with irradiation--8.8%; T3N(+) without radiation therapy--33.3%, with irradiation--33.3%; T4N0 without radiation therapy--33.3%, with irradiation--33.3%, T4N(+) without radiation therapy--33.3%, with irradiation--25.0%. 73 patients (39.3%) had distant metastases as a first symptom of renal cell cancer relapse. The median time to relapse for local recurrence or distant metastases were approximately two times longer in patients with adjuvant radiotherapy compared to those without, 27.0/21.0 months vs. 16.0/12.5 months, respectively. In our opinion postoperative radiotherapy reduces the probability of local recurrences in selected patients, mainly with pathologic stage T3N0, but its impact on survival is minimal.

Adult↗

PubMed1992

[Surgical treatment of funnel chest].

Fourty one patients (33 males and 8 females) with pectus excavatum were operated by Ravitch method modified by Politowski or Drews (36 cases and 5, respectively) from 1980 to 1989. The age of patients ranged from 5 to 25 years (mean 11 years), they were operated because of cosmetic reasons exclusively. Twenty nine of them reappeared to be examined after follow up of 15 months to 10 years (mean 3.5 years). Subjective opinion of the patient, clinical examination and radiological appearance were taken into consideration. There were 72.5% of excellent and good results. No recurrence of the deformity was observed, the most suitable age for the surgery is from 8 to 10 years.

Adolescent↗

PubMed1991

[Electrostimulation in treatment of scoliosis].

The efficiency of electrical stimulation in the treatment of idiopathic scoliosis was assessed on the basis of 95 patients reviewed. In 63% of cases an improvement or inhibition of progression of the curvature was achieved. The infantile and juvenile positive therapeutic effect was found in 70% patients, providing the onset of the therapy took place before the tenth year of life. Adolescent scoliosis were affected by this kind of therapy only to the very little extent.

Adolescent↗

PubMed1990

[Early results of leg bone lengthening using epiphysis-metaphysis distraction].

The methods and results of elongation of the lower extremity by epiphysis-metaphysis distraction obtained at treatment of 13 children aged from 4 to 15 years, with abbreviation of 30-80 mm have been presented. In 11 children full elongation of the abbreviation of 30-57 mm was obtained. In two children full elongation was not obtained.

Adolescent↗

PubMed1988