A family with cardiomyopathy.
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Biomedical subjects
Publications and source records attributed to M Zeltzer.
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The effects of Intralipid (IL) administration of preterm infants have been investigated. For this purpose, adult neutrophils were stimulated by infant sera collected before and after IL treatment. A definite decrease (p less than 0.0005) in chemoattractant capacity of zymosan-activated serum was observed after IL. On the other hand, no difference in the opsinizing abilities of untreated versus treated sera could be demonstrated by measuring the chemiluminescence responses to serum-opsonized zymosan. This study emphasized the need of caution in the use of IL treatment for preterm infants.
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The aim of this study was to improve the rate of detection of hip instability in the neonate. Over a period of 3 years, a pediatric orthopedic surgeon and a neonatal pediatrician both examined 12,891 neonates. During the fourth year, 5,087 newborns were examined by a pediatrician only. Each examiner, working independently, found that 51 babies had neonatal hip instability. In an additional 25 babies, one examiner failed to detect this instability on initial examination. Finally, 36 babies judged to have stable hips at birth later gave cause for orthopedic treatment. These findings strongly suggest that screening should not be restricted to the neonate but should involve several sequential examinations.
Refraction in 67 premature babies was examined and followed during seven years. There was continuous changing of refraction towards emmetropia in all refraction groups. Fifty-four percent of myopic eyes remained myopic at the age of seven years but in all the eyes myopia was of lower degree than at birth. In our series there was no relationship between myopia and RLF.
To summarize the results: Bilirubin removal by hemoperfusion was successfully performed for the first time on a premature infant. The hemoperfusion caused no adverse effects on the clinical state of the infant. The bilirubin removed in 90 min--13 mg--indicates the existence of a large extravascular pool. Hemoperfusion is suggested for bilirubin removal from newborn babies, reducing the need for blood exchange with bank blood.