PubMed Health⌕ Search

Biomedical subjects

M Zibolen

Publications and source records attributed to M Zibolen.

At least 19 recordsLinked to original sources
PubMed1996

Contribution to occupational angiopathy diagnosis using special examination method.

The authors presented 1642 cases of professional diseases caused by vibrations (VD) and 435 cases of extremity overload disease (EOD) diagnosed in the years 1974-1993. In addition to the standard rheoplethysmography there were evaluated the results of digital laser Doppler flowmetry (Moor instruments, UK) in 104 workers exposed to vibration (EV) and 25 controls with the age and smoking habit standardisation. In the selected subgroup were used continual measurements of digital blood pressure (Finapress, Ohmeda), digital LD flux and speed and the measuring of digital skin and central body temperature simultaneously. The records before and after 10 min of local cooling test (Rejsek method) and postocclusive hyperemic tests were summarized (computer evaluation, program STATGRAPHICS, T-test). Vasoconstriction to local cooling persisted in EV for longer time. The records of digital skin flux and speed, digital blood pressure reactions of EV were significantly different (EV/controls) also in the 10th min after cooling. Postocclusion hyperemic tests revealed good functional capacity also in EV. Advantages and disadvantages of methods were discussed. The results found by non-invasive methods in VD were in good relation to images obtained by means of radionuclides (clearance and cumulative tests). Cumulative tests (after 99m--pertechnetate i.v.) can be used in the selected differential diagnostic cases of angiopathies to help to distinguish degree of angiospastic and angioparalytic changes in the hands of VD, and also in special cases at angiopathies connected with EOD.

Adult↗
PubMed1995

[Dynamics of hemodynamic parameters in the early neonatal period].

BACKGROUND: The fetal circulation is subdued to alteration after birth. Fetal vascular communications enclose (ductus arteriosus Botalli and foramen ovale) and vascular resistance of the lungs and pressure in the pulmonary artery decrease. Low-resistance placenta is excluded from the systemic circuit, leading thus to abrupt pressure elevation and to its further increase. OBJECTIVES: The aim of the study is to judge the dynamics of alterations during the postnatal period by means of Doppler's echocardiography:--the left ventricular ventricle,--parameters characterizing circulation in the pulmonary bed. METHODS: 23 healthy randomly selected newborn infants born at full term were examined on the 1st and 2nd day of their life. RESULTS: Parameters of the left ventricular function did not change between the 1st and 2nd days of life. Parameters from the outflow tract of the right ventricle on the 5th day of life of infants: the ratio of PEP (preejection period) to AT (acceleration time) significantly decreased, the ratio of PEP to ET(ejection time) did not change. Parameters of the pulmonary artery on the 5th day of life of infants: significant decrease of the ratio PEP/AT, as well as of PEP/ET, the peak and mean velocity of blood flow significantly increased. CONCLUSIONS: The left ventricular function is not subdued to alterations during early postnatal period. The parameters characterizing the pulmonary circulation prove a decrease of pressure in the pulmonary bed on the 5th day of life. MEANING FOR PRACTICE AND THEORY: The results are utilizable in interpretation of echocardiographic examination in postnatal age. (Fig. 8, Ref. 19.).

Blood Flow Velocity↗
PubMed1993

[Evaluation of blood flow in the renal artery and intraparenchymal arteries in neonates using color doppler sonography].

The authors examined 25 kidneys in 14 healthy neonates in order to evaluate the resistive index (RI) calculated from the maximal systolic and end-diastolic rate of blood flow in the renal artery and some intraparenchymatous arteries. They revealed a significant drop of all absolute rates of blood flow in arteries in the direction to the renal periphery. Consistent with rather few data in the literature, they assessed a normal RI value of intraparenchymatous arteries in healthy neonates (0.76 +/- 0.04) which differs significantly from values assessed in the renal artery (0.82 +/- 0.05) (p < or = 0.001). The authors discuss the normal RI value in the neonatal period. In the conclusion they mention that the RI can be obtained much more easily from the blood flow in the renal artery than the blood flow in intraparenchymatous arteries but the former does not reflect representatively the intraparenchymatous conditions in the kidneys and this restricts its use in evaluations of intraparenchymatous renal processes.

Blood Flow Velocity↗
PubMed1993

[Radionuclide scintigraphy in the diagnosis of Meckel's diverticulum].

In the submitted case-history the authors draw attention to the advantage of radionuclide diagnosis of ectopic gastric mucosae located in Meckel's diverticula. Diagnosis with 99mTc is according to the authors the treatment of choice in acute haemorrhage into the GIT with an obscure aetiology.

Humans↗
PubMed1993

[Neonatal sepsis--still a real problem].

Neonatal sepsis is characterized by bacteraemia and clinical symptoms caused by microorganisms or their toxic products. The authors pay attention to epidemiological and predisposing factors, to the aetiology, pathogenesis, clinical signs and conditions for assessment of the diagnosis of neonatal sepsis as well as its therapy and prognosis.

Bacterial Infections↗
PubMed1989

Contribution to the aetiopathogenesis of orthostatic proteinuria in children: relation to the upper calyx syndrome.

The authors discuss the correlations between the upper calyx syndrome and proteinuria. The syndrome was demonstrated in 33.6 per cent of all children with orthostatic proteinuria hospitalized at the Paediatric Clinic, Martin (Czechoslovakia) during 1978-1985. They consider the possible relations between these conditions that could be mediated by the activation of the renin/angiotensin II system. The direct stimulus of this system could rest in local ischaemization of parenchyma in the region of the proximal pole of the kidney or its partial passive congestion. They assume that these changes become more marked in the standing position and may cause proteinuria of orthostatic character. The inhibition of the renin/angiotensin II system may obviously lead to decreased proteinuria.

Adolescent↗
PubMed1989

[The effect of prednisone in the development of nephropathy in Schoenlein-Henoch purpura].

The authors hospitalized in 1976-1987 39 children with Schönlein-Henoch's purpura who on admission had a normal finding in urine. Of the above patients 28 were given prednisone already at the onset of hospitalization, to 11 prednisone was not administered. Patients with prednisone developed nephropathy in one instance (3.5%), patients without prednisone 6 times (54.5%) which is a significant difference. The average prednisone dose was 1.7 mg per kg body weight per day for an average period of 21 days. Usually for 6-10 days the same dose was administered and then it was gradually reduced.

Child↗
PubMed1988

Incidence of renal complications in Schönlein-Henoch purpura syndrome in dependence of an early administration of steroids.

Between 1976 and 1986, the authors treated 33 children with Schönlein-Henoch purpura (S-H purpura), with physiological urinary finding on admission. Twenty-three of them received prednisone already at the beginning of hospitalization, 10 were not given any prednisone at all. In patients with prednisone, nephropathy occurred only once (4.3%), in those without prednisone it occurred 5 times (50%), the incidence being thus significantly higher. Prednisone was administered in doses ranging between 1.0 and 2.5 mg/kg body mass/day, on an average for 21 days (first 10 days in the same dose, later in reduced doses). Since there is a general lack of data on the positive effect of steroids upon the prevention of nephropathies in S-H purpura, the authors recommend more thorough studies in the initial stage of the disease (before the development of nephropathies).

Child↗
PubMed1988

Heart rate and its variability in juvenile hypertonics during respiratory maneuvers.

In 27 children (14 juvenile hypertonics and 13 healthy control children, with the mean age 14.7 +/- 0.4 y. or 15.2 +/- 0.5 y., respectively, P greater than 0.05) the changes of heart rate (HR), its variability (HRV) during deep inspiration and subsequent expiration, Valsalva's maneuver, doubled breathing frequency and the deepening of breathing were studied. The resting supine mean HR was significantly higher (P less than 0.001) in hypertonics than in controls. Deep inspiration was in both groups accompanied with the HR increase. However, the percentage increase in hypertonics was significantly lower than in normals (P less than 0.02). With subsequent expiration, the HR fell in both groups. There was no significant difference between the percentage decreases in both groups (P greater than 0.05). During the Valsalva's maneuver, in the first phase the tachycardic response occurred, which was in hypertonics significantly less pronounced. After the recovery of breathing a bradycardic reaction occurred which was equal in both groups (P greater than 0.05). Both, in juvenile hypertonics and in controls the doubled frequency of breathing increased the mean HR and decreased the HRV. During the deepened breathing there was an increase in mean HR in both groups, and only in the controls there was an increase in HRV. Heart rate variability in hypertonics was lower than in the controls under all the conditions.

Adolescent↗
PubMed1988

[IgA nephropathy].

Explore the source record for details and available documents.

Glomerulonephritis, IGA↗