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Biomedical subjects

M Zsiray

Publications and source records attributed to M Zsiray.

15 recordsLinked to original sources
PubMed1999

[Transbronchial biopsy in diffuse infiltrative lung diseases].

224 transbronchial biopsies were made between 1990 and 1997 in 208 patients suffering diffuse, bilateral, disseminated pulmonary diseases with unidentified origin. The examinations were carried out by flexible bronchoscope with X-ray control after local anaesthesia. The obtained patterns yielded mucous membrane in 15, intact alveoli in 19 percent. In 25 percent of biopsies (57 cases) definitive diagnosis were verifiable. The histological examinations verified the diagnosis of sarcoidosis, hemosiderosis, TB, malignancies, eosinophil pneumonitis etc. In 71 biopsies (62 cases) according to histological opinion were pulmonary fibrosis or some synonyms of these (alveolitis, interstitial fibrosis). From these latter cases the documentation of 18 patients were insufficient, but the data of 44 cases were available. 7/44 carcinosis, 3/44 inactive TB, 8/44 regressive X-ray patterns were verifiable in this group. The idiopathic pulmonary fibrosis as final diagnosis only in 18/44 (41%) cases were established. Further diagnostic procedures are needed if the clinical data, the results of HRCT and histological examinations are not in correlation.

Biopsy↗
PubMed1995

[Pulmonary echinococcosis].

Two patients with pulmonal Echinococcosis are presented by the authors. Contact with cestoda carrier animals cannot be revealed. At the first patient, who was without any complaints, the two round shadows in her chest X-ray were detected accidentally by screening examination and before the operation only eosinophilia, many eosinophil granulocytes in the pleural effusion and the positive complement binding reaction were related to the Echinococcosis, which was proved by the histological examination of the intraoperative biopsy. The other patient had complaints during months. In this case the Echinococcus granulosus broke into the bronchus and emptied in the sputum. Postoperative histological diagnosis can be obtained by help of the excision from the intraluminal alteration which was visible during bronchoscopy. The authors summarize the etiology, the clinical signs, the diagnose and the therapy of Echinococcosis. They call attention to the incidence of this mainly tropical disease in Hungary and to the rare soliter pulmonal manifestation of the Echinococcosis.

Adult↗
PubMed1995

[Non-malignant cells in pleural fluid].

Insufficient attention has been paid to the cytological examination of cellular elements of the pleural fluid besides or in the absence of tumour cells. 108 cases studied due to pleural fluid were selected. They were characterized by the following: 1. each had histological diagnosis established by either pleuroscopy or by pleural needle biopsy and 2. neither of the samples contained tumour cells. Relationship of the dominant cell type and the ethiology of the pleural fluid was analysed. In case of punctates rich in lymphocytes further cytopathological differentiation is possible, e.g. in case of tuberculotic origin the absence of large mesothelial cells with Giemsa-basophilic cytoplasm is rather characteristic. The use of bioptic methods in the clarification of the origin of pleural fluid is still indispensible.

Biopsy, Needle↗
PubMed1993

[Needle biopsy of the pleura].

A total of 171 pleural needle biopsies were carried out in 123 patients with pleural effusion. The sensitivity of the method proved to be 51% for malignant diseases and 75% for tuberculotic pleurisy, respectively. Performing biopsy simultaneously with the cytological examination of the pleural fluid, malignancy was proved only by needle biopsy in 20% of the patients, while cytology was found negative in these cases. Simultaneously performed thoracocentesis and pleural needle biopsy is suggested.

Adenocarcinoma↗
PubMed1993

Use of Taleum 1-mg inhalation aerosol in bronchial asthma patients.

The effect of 2 sodium chromoglycate products: Taleum 1-mg aerosol (EGIS) and Intal powder capsule (Fisons) has been examined for 4-4 weeks in 15 extrinsic asthma patients by cross-over self-controlled open method. The patients measured peak expiratory flow (PEF) 5 times daily and recorded the time of dyspneic periods in a diary as well as the amount of bronchodilator spray (Berodual, Boehringer) used as adjuvant therapy during dyspnea. The results of the weekly evaluation of the complaints and PEF values proved that both drugs are similarly effective in the prevention of dyspnea caused by bronchial asthma. The adjuvant inhalation betamimetic and anticholinergic drug requirement was lowered, the number, intensity and total time of dyspneic episodes decreased. In the course of the examinations Taleum 1-mg inhalation aerosol proved to be of identical value with Intal powder capsule. Some patients who do not like powder inhalation found the Taleum aerosol drug form to be more advantageous. Side-effect of drug was not observed.

Administration, Inhalation↗
PubMed1992

[Cobalt-induced asthma in workers exposed to hard metal dust].

A case of 39 years old woman with asthma bronchiale associated with cobalt exposure is reported. Specific bronchial provocation tests in these patients supported the diagnosis of hard-metal-induced asthma and implicated cobalt as the agent responsible. The relevant literature data are reviewed.

Adult↗
PubMed1992

[Solitary plasmacytoma of the lung].

A case of solitary plasmacytoma of the lung in a 64 year old woman is reported. The anatomical and clinical features of this exceedingly rare form are discussed. Stress is laid on the 'fact that diagnostic certainty can only be obtained by immunohistochemistry. It is also necessary that patients be subjected to periodical radiological and immunological studies in the postoperative period to detect the possible occurrence of multiple myeloma.

Female↗
PubMed1991

Loderix (setastine) tablets in the treatment of allergic rhinoconjunctivitis.

The effect of a 3-week treatment with Loderix is examined in an open study in 40 patients suffering from allergic rhinoconjunctivitis. Side-effects, mainly sleepiness, fatigue, weakness, were observed in nearly half of the patients. These were, in general, mild and of a transient character. Treatment had to be stopped in 2 patients due to developed adverse effects. Safety parameters as blood picture, liver function tests, renal function parameters showed no alterations during the study course. During the treatment periods rhinoconjunctivitis symptoms disappeared or significantly decreased in 22 patients out of 40. Moderate effect was registered in 14 patients, and treatment was ineffective in 4 cases. In 6 patients the doses were doubled from the 2nd week of treatment causing an increase in effectivity without a change in side-effect profile.

Adolescent↗
PubMed1983

[The effect of conditioning inhaled air in exercise-induced asthma].

The effect of conditioning of the inhaled air on exercise-induced bronchospasm was studied in adult asthmatic patients. In case of inhaling humified air of body temperature, the lung function parameters showed hardly any change after exercise compared to those detected before the test, i.e. the bronchoconstrictive effect of physical exertion could not or hardly be observed.

Air Conditioning↗