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Biomedical subjects

M de Albuquerque

Publications and source records attributed to M de Albuquerque.

6 recordsLinked to original sources

[Models of causal inference: critical analysis of the use of statistics in epidemiology].

The foundations on which the concept of risk has been constructed are discussed. A description of Rubin's model of causal inference, which was first developed in the domain of applied statistics, and later incorporated into a branch of epidemiology, is taken as the starting point. Analysis of the premisses of causal inference brings to light the logical stages in the construction of the concept of risk, allowing it to be understood "from the inside". The abovementioned branch of statistics and epidemiology seeks to demonstrate that statistics can infer causality instead of simply revealing statistical associations; the model gives the basis for estimating that which way be defined as the effect of a cause. Using this procedural distinction between causal inference and association, the model also seeks to differentiate between the epidemiologial dimension of concepts and the merely statistical dimension. This leads to greater complexity when handing the concepts of interation and coofounding. The redective aspects inherent in this methodological construction of risk are here high lighted. Thus, whether applied to individual or populational inferences, this methodological construction imposes limits that need to be taken into account in its theoretical and practical application to epidemiology.

Causality↗

Epilepsy and anxiety.

We have analyzed 155 subjects with STAI (State-Trait Anxiety Inventory): 75 epileptic patients and 80 normal subjects used as a control group. A higher trait-anxiety score (chronic anxiety) than that of controls was found for the epileptic group. For the epileptic group higher levels of the A-trait occurred in patients with EEG abnormalities with left temporal localization. We have also observed that the shorter the epilepsy lasts (less than two years), the higher the trait-anxiety levels. Convulsions and awareness loss during epileptic seizures do not modify state and trait-anxiety scores.

Adolescent↗

[Photosensitivity in primary and secondary epilepsies].

A retrospective study was performed on 34 patients with photosensitivity detected on the electroencephalogram. This group was compared to an aleatory sample, with 218 patients. The objectives were to evaluate the photosensitivity and: type of epilepsy, age of onset of seizures, sex ratio, frequency of seizures, and family history.

Adolescent↗

[Photosensitive epilepsy: report of 2 cases].

Reports on photosensitive epilepsy are uncommon. The authors review the literature, and special attention is given to television epilepsy. Two cases are reported and discussed.

Adolescent↗

[Refractory epilepsies].

STUDY OBJECTIVE: To describe the role of multidisciplinary evaluation and general aspects of intractable epilepsies such as age at the onset, etiologic factors, CT scan findings, electroencephalographic abnormalities, types of epileptic seizures, adherence, and crisis-triggering factors. TYPE OF STUDY: Retrospective. SITE: Department of Epilepsy Research and Treatment (SITE)--São Paulo, Brazil. PATIENTS: Analysis encompassed 80 epileptic patients registered with the SITE, who had one or more crises per week, with a minimum follow-up of one year, older than 13 and seen between August and October 1989. INVESTIGATIONS: psychologic, social, nursing, and neurologic evaluations. Treatment performed with antiepileptic drugs. MEASUREMENTS AND RESULTS: Mean age at onset of epilepsy = 12.6 years; 70% of patients have symptomatic partial epilepsy; 66.2% had epilepsy onset after 5 years of age; 80% have had epilepsy for more than 10 years; etiology was not determined in 47.5% of the cases and, in 22.5%, it was due to neurocysticercosis; 88.7% of the patients were having anti-epileptic polytherapy; 50% of the patients did not adhere to the treatment; 56.25% reported emotional originating factors; 60% were socially non-adjusted; 30% had abnormal EEG in the right temporal lobe; 26.2% in the left temporal lobe; 21.2% had normal EEG plotting, and the remainder had their EEG with focal abnormalities in other locations. CONCLUSIONS: The authors accept the fact that a patient who does not lead a balanced social, affective, and emotional life should be classified as a probable case of intractable epilepsy. The authors observed that a large portion of the patients could be seen as pseudodifficult treatment cases, since 50% were non-adherent to treatment, and 56.25% reported the presence of emotional originating factors. As most of these patients have social and psychological maladjustments, perhaps due to their high incidence of epileptic crises, they may be cases of intractable epilepsies.

Adolescent↗