PubMed Health⌕ Search

Biomedical subjects

M von Ditfurth

Publications and source records attributed to M von Ditfurth.

7 recordsLinked to original sources
PubMed1990

[The value of functional tests in diagnosis of prolactinoma].

The present study in 37 hyperprolactinaemic patients was performed, to investigate the relationship between radiographic changes of the pituitary region and serum prolactin levels, clinical signs and the results of dynamic tests. Prolactin responsiveness after metoclopramide- and TRH-injection and the nocturnal profile of serum prolactin were examined in 25 women. The results of the dynamic tests did not correlate with the radiological diagnosis. However, serum prolactin concentrations correlated strongly with the radiographic evidence of a pituitary tumour. The results show, that prolactin stimulation tests and the evaluation of the nocturnal secretory pattern of prolactin are not useful for differentiating between adenoma and nonadenoma caused hyperprolactinaemia. However, determinations of prolactin serum levels are of great clinical importance in the diagnosis of prolactinomas.

Circadian Rhythm↗
PubMed1989

[Immunologically-induced abortion--diagnosis and therapy].

As etiological factors responsible for repeated miscarriages disturbances of the maternal-fetal immunoregulation are involved. Diagnostic aspects of the immunobiology of abortion and the clinical management of habitual abortion by immunotherapy are discussed.

Abortion, Habitual↗
PubMedDate not supplied

[The immunologically-caused early abortion].

Recent advances in the understanding of immunological events during pregnancy offer new diagnostic and therapeutic approaches to couples suffering from unexplained recurrent spontaneous abortion. In terms of immunology the success of pregnancy means, that the fetus as a semi-allogeneic graft is not rejected by the mothers/recipients immune system. Beside a variety of specific and non-specific mainly locally acting substances a process of active tolerance induction is responsible for fetal survival. In response to paternally inherited fetal antigens the maternal immune system produces so-called blocking factors. In most women with unexplained recurrent spontaneous abortion these blocking factors cannot be detected. By immunization with paternal or third party lymphocytes the maternal immune system can be stimulated to produce blocking factors and therefore to protect a conceptus from rejection.

Abortion, Habitual↗