Biomedical subjects

M von Hülst

Publications and source records attributed to M von Hülst.

2 recordsLinked to original sources

PubMed1988

[Increased secretion of vasopressin and edema formation in high dosage methotrexate therapy].

During high-dose methotrexate therapy we recognized a significant increase in AVP secretion as it has previously been reported for other cytostatics. We observed an excessive augmentation of AVP excretion in 24 h urine in 9 patients receiving high-dose methotrexate combined with a considerable water retention. The pathomechanism is so far unknown. From experimental data it may be assumed that methotrexate alters directly the neurosecretory areas of the cerebrum as well as effects the distribution of body fluid volumes. The considerable risk of a water intoxication seems to be of highly clinical importance.

Arginine Vasopressin↗

PubMed1987

[Advanced pulmonary alveolar microlithiasis].

A severe course of microlithiasis alveolaris pulmonum in a 28-year old patient is described. The disease, which had progressed to a very advanced stage at the time of examination, produced in the plain radiograph of the thorax an extensive, homogeneous, ground-glass like shadow of practically all organs of the thorax. The typical miliary (spot-like) shadow ("sandstorm lung") is visible only in the lateral and apical parts of the lung. CT revealed massive calcareous deposits which increased in craniocaudal and ventrodorsal direction. Bullous metaplasia of the lung was particularly striking in the apical region. No effective therapy is known so far. A combined heart and lung transplantation might be the only therapy that could prolong the patient's life.

Adult↗