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Biomedical subjects

MJ Penner

Publications and source records attributed to MJ Penner.

3 recordsLinked to original sources

Rating the Annoyance of Synthesized Tinnitus.

Ten tinnitus sufferers mimicked the sensation caused by their tinnitus with a complex sound pattern consisting of the sum of sine waves. The annoyance of these ten sounds was then rated on a scale from 1 (not annoying) to 10 (very annoying) by some of the tinnitus sufferers and by 50 normal-hearing subjects. For the normal-hearing subjects, the number assigned to rate the annoyance of each sound varied widely from subject to subject, while the rank ordering of the ratings was in rough agreement. Because rankings have less inter-subject variability than ratings, ranking are likely preferable as a dependent variable in the clinical assessment of tinnitus. The correlation between the ratings of the ten stimuli by the subjects with normal hearing and the subjects with tinnitus averaged 0.90, indicating that the tinnitus sufferers and the normal-hearing subjects tended to judge the annoyance of the sounds in a similar fashion. Further, the rating of the subject's own tinnitus lay near the regression line, indicating that the subject judged his own tinnitus imitation no differently than he judged the annoyance of other sounds.

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Masking Patterns for Partially Masked Tinnitus.

Tinnitus isomasking contours were determined for unmasked tinnitus and for tinnitus partially masked by high-pass noise. The noise was selected so that it masked all but the low frequency components of the tinnitus. As a control, the masking pattern of an external tone in the tinnitus region and in the presence of the high-pass noise was compared with that of the partially masked tinnitus. Frequency-specific masking was obtained for the external tone but not for the partially masked tinnitus. This suggests that even narrowband tinnitus is not masked in the cochlea. Thus, tinnitus maskers need not include the frequency region presumed to contain the tinnitus.

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Tinnitus Synthesis: Fluctuant and Stable Matches to the Pitch of Tinnitus.

Five subjects mimicked the sensation caused by their tinnitus with a complex sound pattern consisting of the sum of sine waves. The imitation tinnitus was generally broadband, spanning an average of 2.94 kHz. Measures of the pitch of the tinnitus were made using both a forced-choice double-staircase (FCDS) task and a method of adjustment (MOA) task. Even tinnitus portrayed as broadband was matched reliably using a FCDS task, presumably because all but one component of the tinnitus was ignored. With the MOA task, successive matches to the predominant tinnitus pitch were fluctuant, presumably because disparate components of the tinnitus were subsequently matched. Because tinnitus is a broad-band signal, clinical trials evaluating the effect of a treatment on tinnitus should involve assessing changes occurring at any location in tinnitus spectrum.

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