Biomedical subjects

Madeline J Eacott

Publications and source records attributed to Madeline J Eacott.

4 recordsLinked to original sources

PubMed2006

Memories of early childhood: qualities of the experience of recollection.

Memories judged to be recollections were contrasted with memories known to be based on second-hand sources in order to investigate the phenomenological qualities that underlie the experience of recollection. Adults rated the qualities of their recollections of an early childhood experience. Their ratings were compared with ratings of the qualities of memories of a similar autobiographical experience where the information was known to derive from other sources. Reported recollections were rated higher than memories based on other sources for many qualities, including sensory and spatial detail, location, thoughts, feelings, completeness, event detail, and pictorial representation. Comparison of the ratings of memories dating from different ages suggests that a memory may be judged to be recollected even if only a subset of the qualities characterizing recollections are present. This provides partial support for and clarification of Rubin's multiple-systems model of autobiographical memory.

Adult↗

PubMed2005

Recollection in an episodic-like memory task in the rat.

Episodic memory in humans is the conscious recollection of a past event. Animal models of episodic-like memory assess the memory for "what"happened, "where" it happened, and either "when" it happened, or in "which" context it happened, although recollection on such tasks is often difficult to measure. Here we present the first evidence of successful recollection of a past event in a rat in a task which is easily performed, requires little training, and is easily adaptable for other commonly used laboratory species.

Animals↗

PubMed2005

Visual memory loss and autobiographical amnesia: a case study.

Amnesia typically results from trauma to the medial temporal regions that coordinate activation among the disparate areas of cortex that represent the information that make up autobiographical memories. We proposed that amnesia should also result from damage to these regions, particularly regions that subserve long-term visual memory [Rubin, D. C., & Greenberg, D. L. (1998). Visual memory-deficit amnesia: A distinct amnesic presentation and etiology. Proceedings of the National Academy of Sciences of the USA, 95, 5413-5416]. We previously found 11 such cases in the literature, and all 11 had amnesia. We now present a detailed investigation of one of these patients. M.S. suffers from long-term visual memory loss along with some semantic deficits; he also manifests a severe retrograde amnesia and moderate anterograde amnesia. The presentation of his amnesia differs from that of the typical medial-temporal or lateral-temporal amnesic; we suggest that his visual deficits may be contributing to his autobiographical amnesia.

Adult↗

PubMed2004

Integrated memory for object, place, and context in rats: a possible model of episodic-like memory?

We report an investigation into memory for an object, its spatial location, and the context in which it appeared in rats. A novel task based on the spontaneous recognition paradigm is presented that requires memory for these three aspects. This task is performed easily by intact rats at delays of up to 1 hr. However, performance of the task is severely and selectively disrupted by transection of the fornix. Ability to perform this task is discussed in relation to models of episodic memory in animals, and we suggest that this task provides a simple and useful animal model of episodic memory for use with rats.

Animals↗