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Madersbacher

Publications and source records attributed to Madersbacher.

2 recordsLinked to original sources

[Conservative drug therapy of neurogenic bladder disorders].

Today neuropharmacas are a helpful part in the conservative treatment of the neurogenic bladder disorders. They are, or course, no "wonder-drugs" and usually lead to an improvement only of the troubles, but rarely to complete cure. If monotherapy does not lead to the results wanted, one should combine drugs of the same of similar effects but with different pharmacologic targets. A real progress was reached through alpha-receptor-blockers, whose use has, especially in children with myelomeningocele, changed the therapeutic concept in favour of a largely conservative treatment. We already know a number of substances that in one way or other influence the muscles of the bladder and the bladder outlet. If only part of them will reach clinical usage, it can be assumed that the pharmacotherapy will become even more meaningful in the treatment of neurogenic bladder disorders.

Adrenergic alpha-Antagonists↗

Urinary flow and flow pattern in paralegics.

In 34 paraplegics with neurogenic bladder dysfunction 108 uroflowmetries were performed using the uroflowmeter described by Garrelts and Strandell. Paraplegics show according to their pathophysiology of bladder emptying characteristic flow pattern. Their urinary flow rates are diminished. The decrease as compared with healthy people is nearly similar for patients with automatic and with autonomous areflexic bladders. Some pathophysiological aspects for these findings are discussed. One may conclude that decreased urinary flow and altered flow pattern, as changes of urodynamics in general, can be regarded as one of the factors causing recurrent bacteriuria and urinary infections in paraplegics.

Adult↗