PubMed Health⌕ Search

Biomedical subjects

Madhulika

Publications and source records attributed to Madhulika.

At least 19 recordsLinked to original sources
PubMed2000

Multidrug-resistant typhoid fever.

One hundred children (consecutive) with positive blood culture for Salmonella typhi were studied for clinical profile and complications. The common clinical features were fever (100%), vomiting (58%), abdominal pain (48%), cough (22%) and loose stools (14%) and the Widal test was positive in 75% patients. Eighty per cent of the salmonella isolates were resistant to amoxycillin, chloramphenicol and co-trimoxazole drugs, but all were sensitive to ciprofloxacin and ceftriaxone. Forty patients developed complications: encephalopathy (18), melaena (12), haematemesis (10), epistaxis (4), hepatitis (4), acalculous cholecystitis (4), bowel perforation (3) and nephritis (2). Complications were more frequent in children with multidrug-resistant typhoid. The final antibiotic required to render the children afebrile included ciprofloxacin (80), ceftriaxone, amoxycillin (4), chloramphenicol (4), amoxycillin and gentamicin (4), amoxycillin with chloramphenicol (2), and furazolidone (2). The defervesence time was least with ceftriaxone and greatest with amoxycillin. All the affected children made a complete recovery.

Anti-Bacterial Agents↗
PubMed1995

Sarcoidosis.

Explore the source record for details and available documents.

Child↗
PubMed1994

Vitamin A supplementation in post-measles complications.

One-hundred-and-seventy-seven children with post-measles complications divided into two comparable groups were studied for the effect of Vit.A Supplementation. Eighty-nine children received Vit.A in doses of 200,000 units daily on two consecutive days in addition to antibacterials and other supportive care and 88 did not reveice Vit.A. The case fatality rate was 16 per cent in those who received VIT.A, while the same was 32 per cent in those who did not receive Vit.A (P < 0.02). There was no statistical difference in the mortality rate among two groups when the children were suffering from severe malnutrition or encephalopathy (P > 0.1).

Anti-Bacterial Agents↗
PubMed1989

Upper and lower limb standards in newborn.

One thousand live born babies of various gestational ages were studied. Using standard techniques, various limbs anthropometric measurements were taken with a non-stretchable measuring tape. Normal values and S.D. for each gestational week were calculated and their relation with gestational age statistically analysed. All these measurements correlated with gestational age. Foot length correlated best with gestational age amongst all the measurements (r = 0.9399).

Anthropometry↗
PubMed1989

Blood pressure studies in Jaipur children.

A total of 1500 apparently healthy children between 1-12 years of age were examined. Blood pressure (BP) readings were taken and standard deviation and percentiles worked out for different sexes and age groups. Prevalence of hypertension was found to be 2.86% in males and 2.97% in females in 5-12 years of age group. Obesity was prevalent in 24% of the hypertensive cases. A higher value of serum cholesterol as compared to controls was also seen in the hypertensive group.

Blood Pressure↗
PubMedDate not supplied

Diagnosis of cystic fibrosis: Indian perspective.

Cystic fibrosis (CF) is one of the common life limiting inherited diseases in Caucasian population. Recent reports suggest that the diagnosis of cystic fibrosis in Indian children is missed or delayed due to low index of suspicion. The diagnosis of cystic fibrosis is suspected by the typical clinical features and should be confirmed by doing sweat chloride estimation. If sweat test is not available, ancillary tests including blood electrolyte and acid base balance, airway microbiology, tests to identify pancreatic insufficiency and semen analysis for obstructive azoospermia in post pubertal boys should be carried out. Positive results of these tests make the suspicion very strong. A strongly suspected case should be treated as cystic fibrosis, but for giving a diagnosis of CF, sweat test should be done from the nearest centre where it is available. In the presence of typical clinical features with borderline sweat chloride values sweat test should be repeated 2-3 times and the child should be investigated for alternative diagnosis. In the absence of alternative diagnosis with consistently high or borderline sweat chloride values an attempt should be made to get tests for mutations.

Child↗
PubMedDate not supplied

Neonatal sepsis due to vertical transmission from maternal genital tract.

High vaginal swabs (HVS) of 1792 expectant mothers were sent for culture at the time of delivery, prior to first vaginal examination. The newborns were followed-up for development of superficial or deep infections. Appropriate cultures of the babies who developed infections were sent. Bacterial growth of predominantly gram-ve organisms was obtained in 1026 (57%) HVS. Infection developed in 48 (27%) babies in 1st 72 hours of life, of which 28 had deep infection while the rest had superficial infection. Vertical transmission of organisms was documented in 24 (1.3%) mother-baby dyads and the same was 72% in newborns who were at risk of developing sepsis by septicemia scoring, showing a significantly higher incidence of vertical transmission and subsequent sepsis in high risk newborns.

Bacterial Infections↗