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Magali Zappa

Publications and source records attributed to Magali Zappa.

4 recordsLinked to original sources

Prevalence of hepatic hemangioma in patients with focal nodular hyperplasia: MR imaging analysis.

PURPOSE: To evaluate the prevalence of hepatic hemangioma in a large population of patients with focal nodular hyperplasia (FNH) and to determine if the prevalence is higher than that in patients with other hepatic masses. MATERIALS AND METHODS: Over a period of 40 months, 247 patients with one or more hepatic masses underwent magnetic resonance (MR) imaging at our institution and met the inclusion criteria for this study. One hundred forty-eight patients received a diagnosis of FNH (study group). Ninety-nine patients had a lesion other than FNH and had no history of chronic liver disease (control group). Imaging findings of the main lesion and presence of associated hemangioma were investigated. chi2 analysis was used to determine if there was a statistically significant difference in the two groups regarding the number of patients with associated masses. RESULTS: Twenty-nine of 148 patients (20%) in the study group had FNH with one or more associated hepatic hemangiomas. Among the 99 patients in the control group, nine (9%) had an associated hemangioma. The prevalence of hemangioma was significantly higher (P <.02) in the study group than in the control group. The prevalence of hemangioma in patients with a solitary FNH lesion compared with that in patients with multiple FNH lesions was not significantly different. CONCLUSION: Patients with FNH are more likely to have an associated hepatic hemangioma than are those with another type of focal hepatic mass.

Adult↗

Portal cavernoma-associated cholangiopathy: a clinical and MR cholangiography coupled with MR portography imaging study.

Although biliary symptoms appear to be uncommon in patients with portal cavernoma, almost all of them have endoscopic retrograde cholangiographic abnormalities. The mechanisms underlying the biliary changes are explained poorly. This study in patients with portal cavernoma had 3 aims: (1) to assess the manifestations related to biliary involvement; (2) to evaluate with magnetic resonance (MR) imaging the aspect and frequency of cholangiographic changes; and (3) to clarify the mechanisms underlying biliary involvement. From December 1999 to July 2001, 25 consecutive adults with portal cavernoma without cancer or cirrhosis were studied with MR cholangiography coupled with MR portography. Seven patients presented with clinical manifestations of biliary disease. MR cholangiography findings were stenosis in 21 patients, with upstream dilatation in 16 and displacement in 13. MR cholangiography coupled with MR portography showed in all cases that the biliary abnormalities were secondary to a mass effect directly related to pressure by the cavernoma. In conclusion, in patients with portal cavernoma, clinical manifestations of biliary disease are most frequent; the cholangiographic abnormalities are very common and usually are caused by a mass effect by pressure from the veins composing the cavernoma. MR cholangiography coupled with MR portography is an effective noninvasive examination for simultaneous visualization of bile ducts and their relationship to the cavernoma.

Bile Duct Diseases↗