Biomedical subjects

Magdalena Pilas-Pomykalska

Publications and source records attributed to Magdalena Pilas-Pomykalska.

3 recordsLinked to original sources

PubMed2005

[Retinal capillary blood flow in nonexudative age-related macular degeneration].

PURPOSE: The purpose of this study was to evaluate retinal capillary blood flow in patients with nonexudative age-related macular degeneration. MATERIAL AND METHODS: Twenty five patients with nonexudative age-related macular degeneration and twenty five age-matched control subjects were enrolled into the study. Full ophthalmological examination and fluorescein angiography were performed. Retinal blood flow was evaluated with the Heidelberg Retina Flowmeter. Total mean flow and mean velocity were calculated using the technique of automatic full field perfusion image analysis RESULTS: Patients with nonexudative age-related macular degeneration revealed statistically significant lower retinal blood flow than control subjects. In AMD group total mean flow values were 266.89 / 272.21 AU, while in control group were: 1.498 / 1.509 AU. Mean velocity values were: 1.315 / 1.329 AU in AMD patients and: 1.498 / 1.509 AU in controls. CONCLUSIONS: The study results showed reduced capillary retinal blood flow in patients with age-related macular degeneration compared to normal subjects. This retinal microcirculation impairment suggests more generalized perfusion defect involving both, choroidal and retinal blood flow.

Blood Flow Velocity↗

PubMed2005

[Ocular changes during pregnancy].

Pregnancy is often associated with ocular changes. Most of them are specifically associated with the pregnancy itself, rare disturb the normal visual function and are transient in nature. The ocular effects of pregnancy may be divided into physiologic changes, pathologic conditions or modifications of pre-existing conditions. Pregnancy is associated with changes in corneal sensitivity and thickness, decreased tolerance to contact lenses, decreased intraocular pressure, can affect refractive error. Pathologic conditions reported to develop during pregnancy include hypertensive and vascular disorders, central serous chorioretinopathy, uveal melanoma and others. The most significant modified pre-existing condition is diabetes mellitus. Pregnant women are at increased risk for the progression of preexisting proliferative diabetic retinopathy, and diabetic women should see an ophthalmologist before pregnancy or early in the first trimester. This review describes various ocular changes that occur during pregnancy and summarizes the ocular disturbances in these three categories.

Adult↗

PubMed2004

[Changes in intraocular pressure during pregnancy].

PURPOSE: The purpose of this study was to define physiological changes in intraocular pressure during pregnancy. MATERIAL AND METHODS: 182 healthy pregnant women were examined cross-sectionally throughout the pregnancy. After measuring systolic and diastolic blood pressure full ophthalmological examination was performed (visual acuity, refractive error, intraocular pressure, slit lamp examination and fundus exam). All subjects were free from any systemic or ocular diseases. RESULTS: Intraocular pressure significantly decreased during successive stages of pregnancy. The results are presented as means SD. In the control group mean IOP was 15.6 +/- 1.81 mmHg. During first ten weeks of pregnancy mean IOP was 15.33 +/- 1.98 mmHg, between 11-20 hbd was 14.52 +/- 2.37 mmHg, between 21-30 hbd was 13.47 +/- 2.19 mmHg, and towards the end of pregnancy (31-40 hbd) was 12.5 +/- 1.96 mmHg. The mean fall of IOP during whole pregnancy was 3.1 +/- 0.38 mmHg (p < 0.001). In these subjects pregnancy decreased IOP by 19.8%. CONCLUSIONS: The study results showed a gradual, statistically significant fall of intraocular pressure during pregnancy.

Adult↗