Biomedical subjects

Mahiuddin Alamgir

Publications and source records attributed to Mahiuddin Alamgir.

4 recordsLinked to original sources

PubMed2006

Assessment of antidiarrhoeal activity of the methanol extract of Xylocarpus granatum bark in mice model.

The methanol extract of Xylocarpus granatum bark was studied for its antidiarrhoeal properties in experimental diarrhoea, induced by castor oil and magnesium sulphate in mice. At the doses of 250 and 500 mg/kg per oral, the methanol extract showed significant and dose-dependent antidiarrhoeal activity in both models. The extracts also significantly reduced the intestinal transit in charcoal meal test when compared to atropine sulphate (5 mg/kg; i.m.). The results showed that the extracts of Xylocarpus granatum bark have a significant antidiarrhoeal activity and supports its traditional uses in herbal medicine.

Animals↗

PubMed2006

Triglycerides from Urena lobata.

Two triglycerides, both bearing polyunsaturated fatty acid residues, were isolated from the hexane extract of Urena lobata. One of them is characterized by the presence of three different polyunsaturated fatty acids. Their structures were studied with spectral methods.

Humans↗

PubMed2006

Antioxidant and 15-lipoxygenase inhibitory activity of rotenoids, isoflavones and phenolic glycosides from Sarcolobus globosus.

From Sarcolobus globosus, two rotenoids (villosinol and 6-oxo-6a,12a-dehydrodeguelin), one isoflavone (genistin) and four phenolic glycosides (vanillic acid 4-O-beta-d-glucoside, glucosyringic acid, tachioside and isotachioside) were identified for the first time from this species. Extracts and compounds from S. globosus were evaluated for their DPPH radical scavenging and 15-lipoxygenase (15-LO) inhibitory activities. All tested rotenoids were found to inhibit 15-LO, while they lacked DPPH radical scavenging effect.

Antioxidants↗

PubMed2005

Rotenoids and isoflavones from Sarcolobus globosus.

Sarcolobus globosus is a medicinal plant growing in mangrove forests in Asia. No constituents from this plant have been reported previously. From the diethyl ether extract of S. globosus a new rotenoid sarcolobin and a new isoflavone sarcolobone, as well as the previously known rotenoids tephrosin, 12aalpha-hydroxydeguelin, 11-hydroxytephrosin, 12a-hydroxyrotenone, 12aalpha-hydroxyrotenone, 6aalpha,12aalpha-12a-hydroxyelliptone, 6a,12a-dehydrodeguelin, 13- homo-13-oxa-6a,12a-dehydrodeguelin, the isoflavone barbigerone and a chromone 6,7-dimethoxy-2,3-dihydrochromone were identified. 6,7-Dimethoxy-2,3-dihydrochromone has not previously been reported as a natural product.

Apocynaceae↗