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Maido Castiglioni

Publications and source records attributed to Maido Castiglioni.

5 recordsLinked to original sources
PubMed2006

Amylase: a disease activity index in multiple myeloma?

This study reports a case of a patient with lambda-light chain multiple myeloma who developed a high hyperamylasaemia of the salivary type during the disease and soon afterwards died. Ectopic production of amylase by myeloma cells has been described in a few cases and demonstrated by tissue culture and immunohistochemical techniques. The common characteristics of these cases were: salivary amylase isoenzyme increase, high tumor mass, extensive extra-medullary spread, extensive bone destruction and poor prognosis. In patients with amylase-producing multiple myeloma, the onset of hyperamylasaemia heralds a rapid disease progression; therefore, in these patients, a simple test such as serum amylase may represent a reliable disease activity index and provide an additional prognostic information.

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PubMed2006

[Heart failure and cholelithiasis].

We previously found an high incidence of gallstone or cholecystectomy for lithiasis in patients affected by heart failure (52.1% up to 58.6%). As in general population the incidence of this disease is up to 38%, we tried to explain our findings.

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PubMed2005

[Atrial fibrillation and thyroid gland].

Many diseases can lead to atrial fibrillation and one of these is thyroid disfunction. The prevalence of atrial fibrillation does not differ between subclinical and overt hyperthyroidism. Hypothyroidism also can be associated to atrial fibrillation. Low-T3 syndrome is considered a risk factor in cardiac patients. In 100 patients affected by atrial fibrillation we studied the thyroid function and performed ultrasound examination of the thyroid gland. 30 patients had a low-T3 syndrome, 66 (38 > or =10 mm) patients had thyroid nodules, while just 10 patients had an abnormal thyroid function. So, in patients affected by atrial fibrillation, we suggest to study the levels of thyroid hormones and, even if these are normal, to perform an ultrasound examination of the gland.

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