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Biomedical subjects

Manuel Pérez-Miranda

Publications and source records attributed to Manuel Pérez-Miranda.

6 recordsLinked to original sources
PubMed2006

Use of self-expanding metal stents to treat malignant colorectal obstruction in general endoscopic practice (with videos).

BACKGROUND: Self-expanding metal stents (SEMS) are being increasingly used to solve malignant colorectal obstruction (MCRO). Patients can then either undergo scheduled surgery or have the stent left in place as a definitive palliative treatment. The majority of reports on the use of SEMS in MCRO come from single centers; therefore, its use in general endoscopic practice is not clearly known. OBJECTIVE: To study the use of SEMS for MCRO in a wide endoscopic practice. DESIGN: Retrospective study. SETTING: A survey was carried out among endoscopists in 13 hospitals in Spain (6 tertiary referral centers and 7 community hospitals). PATIENTS: Those who presented with MCRO. INTERVENTIONS: A total of 175 attempts to insert colorectal SEMS were made during a 12-month period (October 2003 to September 2004). MAIN OUTCOME MEASURES: Technical and clinical success and possible differences according to the type of hospital. RESULTS: There was a mean of 1.2 attempts/mo per center (range, 2-0.5 attempts/mo per center). Insertion success was achieved in 162 (92.6%) and acceptable colonic decompression in 138 of 175 (78.8%) attempts and in 138 of 162 (85.1%) of successfully inserted stents. SEMS served as a bridge to scheduled surgery in 72 of 175 (41%) and as a palliative definitive treatment in 66 of 175 (37.7%). The major complication was perforation, which occurred in 7 of 175 occasions (4%) and led to death in 2 patients (1%). There were other less severe complications (25 [14%]). No significant differences in outcome of stent placement procedures were found between both categories of centers. LIMITATIONS: Retrospective study involving many centers and the possibility of bias for different assessments of outcomes. CONCLUSIONS: In this study, success rates for SEMS placement and colonic decompression in MCRO were acceptable, without substantial differences according to the type of hospital. This procedure appeared to be feasible in general endoscopic practice.

Adult↗
PubMed2005

Predictors of an intermediate ventilation/perfusion lung scan in patients with suspected acute pulmonary embolism.

BACKGROUND: An intermediate ventilation/perfusion (V/Q) lung scan lacks diagnostic utility in excluding acute pulmonary embolism (PE). OBJECTIVE: To identify the potential predictors of an intermediate V/Q lung scan in patients with suspected acute PE. METHODS: A review of the medical records of 306 consecutive patients with suspected acute PE, in whom a V/Q lung scan was performed (interpretation using modified Prospective Investigation of Pulmonary Embolism Diagnosis criteria). RESULTS: A total of 274 patients (89.5%) had a non-intermediate V/Q lung scan: 88 (28.8%) high probability, 149 (48.7%) low probability, and 37 (12.1%) near normal/normal. Thirty-two patients (10.5%) had an intermediate V/Q lung scan. Patients with an intermediate V/Q lung scan presented a significantly greater frequency of age greater than 70 years (81.2 versus 50.4%, P=0.01), previous cardiopulmonary disease (75 versus 46.3%, P=0.003), chronic obstructive pulmonary disease (34.4 versus 15.7%, P=0.01), and chest radiograph evidence of emphysema (18.7 versus 4.7%, P=0.008). We found no other significant differences in the rest of the characteristics studied between patients with an intermediate and a non-intermediate V/Q lung scan. CONCLUSION: The possibility of an intermediate V/Q lung scan is higher in elderly patients and in patients with previous cardiopulmonary disease (especially with chronic obstructive pulmonary disease). Emphysema is the only chest radiograph abnormality associated with a greater possibility of an intermediate V/Q lung scan.

Aged↗
PubMed2004

Low-grade and high-grade fever at presentation of acute pulmonary embolism.

We retrospectively reviewed the medical records of 154 consecutive patients with acute pulmonary embolism (PE) admitted to an Internal Medicine Service. At presentation, fever (temperature > 37 degrees C) without other identified causes was present in 28 patients (18.2%): 27 patients had low-grade fever (temperature 37-39 degrees C) and one patient had high-grade fever (temperature > 39 degrees C). Epidemiological and clinical characteristics, electrocardiographic and chest radiograph abnormalities and mortality rate were similar in patients with and without fever. Fever, including high-grade fever, is a possible presenting feature in patients with acute PE. Patients with acute PE and fever have similar characteristics compared with those without fever.

Acute Disease↗
PubMed2004

Syncope in acute pulmonary embolism.

BACKGROUND: Syncope is a possible but little known presenting manifestation of acute pulmonary embolism (PE). The importance of syncope at the presentation of acute PE is not known. OBJECTIVES: To report the frequency and to establish the prognostic significance of syncope at the presentation of acute PE. METHODS: A retrospective review of the records of 154 consecutive patients admitted to an Internal Medicine service with acute PE. RESULTS: Fourteen patients with acute PE (9.1%) had syncope at presentation. Epidemiological and clinical characteristics (including respiratory failure, right heart failure and arterial hypotension), and hospital mortality were similar in patients with or without syncope. CONCLUSIONS: Syncope is not an uncommonly presenting manifestation of acute PE. Patients with acute PE and syncope have similar characteristics to those without syncope. Syncope does not seem to determine a poor prognosis.

Acute Disease↗
PubMed2003

Wheezing in patients with acute pulmonary embolism with and without previous cardiopulmonary disease.

BACKGROUND: Wheezing is a little known but possible presentation feature of acute pulmonary embolism. PATIENTS AND METHODS: A retrospective review of the records of 154 consecutive patients with acute pulmonary embolism, who survived long enough for diagnostic evaluation. RESULTS: Fourteen patients with acute pulmonary embolism (9.1%) had wheezing at presentation. Wheezing was more frequent in patients with previous cardiopulmonary disease than in those without previous cardiopulmonary disease, although this did not reach statistical significance (13.5 versus 6.9%; P=0.17). Dyspnoea, cough and respiratory failure were more frequent with statistical significance in our patients with wheezing than in those without wheezing. The hospital mortality rate was similar in both groups. CONCLUSION: Wheezing in acute pulmonary embolism may be more frequent in patients with previous cardiopulmonary disease. However, wheezing also occurs in patients with acute pulmonary embolism without previous cardiopulmonary disease. Wheezing may be a sign of severity in acute pulmonary embolism.

Acenocoumarol↗