Biomedical subjects

María G Crespo Leiro

Publications and source records attributed to María G Crespo Leiro.

4 recordsLinked to original sources

PubMed2006

[Heart failure in 2005].

This article is a review of developments reported in the field of heart failure in the last year. It covers advances in epidemiology, pathophysiology and therapy, including cardiac resynchronization therapy and heart transplantation. Today, management of heart failure is complex. It depends on the participation of numerous health professionals under the guidance of a cardiologist. The increasing prevalence of heart failure means that continuing research is mandatory.

Heart Failure↗

PubMed2006

[Epidemiology of heart failure in Spain and the importance of adhering to clinical practice guidelines].

This article focuses on the magnitude of the challenge of heart failure, with particular reference to the disease burden in Spain. The text also deals with the difficulty of estimating the size of the problem, which stems from the fact that heart failure is a common end-point of numerous conditions. The second part of the article presents some reflections on the value of clinical practice guidelines and on the difficulty of incorporating interventions that have proven their efficacy under the controlled conditions of a clinical trial into everyday clinical practice, thereby maximizing their potential benefits. Finally, some suggestions are made on improving both professionals' adherence to clinical practice guidelines and patients' adherence to recommended treatment.

Aging↗

PubMed2006

[Heart failure. Are women different?].

The clinical syndrome of heart failure is very common in women. In fact, the majority of heart failure patients in the general population are female, in particular elderly women and women with a preserved ejection fraction. There are differences between heart failure in women and men in terms of epidemiology, pathogenesis, treatment response, and quality of care. The incidence is greater in men, but the prevalence at more advanced ages is higher in women. Prognosis seems to be better in women, although the mechanism responsible is not well understood. Clinical trials of heart failure have included fewer women than men, and this has limited our understanding of the efficacy of heart failure treatment in this group of patients.

Female↗

PubMed2004

[Management of advanced or refractory heart failure].

Advanced heart failure, also be defined as stage D heart failure, characterized by advanced structural heart disease and marked symptoms of heart failure at rest despite dietary modification, salt restriction and maximal medical therapy including ACE inhibitors, angiotensin II receptor blockers, digitalics, diuretics and beta blockers. These patients require frequent hospitalizations and specialized interventions such as heart transplantation, implantation of mechanical assistance devices, continuous intravenous inotropic therapy to palliate symptoms, or continued terminal care.

Cardiovascular Agents↗