PubMed Health⌕ Search

Biomedical subjects

María-José Corral

Publications and source records attributed to María-José Corral.

2 recordsLinked to original sources
PubMed2005

Abnormal speech sound representation in persistent developmental stuttering.

OBJECTIVES: To determine whether adults with persistent developmental stuttering (PDS) have auditory perceptual deficits. METHODS: The authors compared the mismatch negativity (MMN) event-related brain potential elicited to simple tone (frequency and duration) and phonetic contrasts in a sample of PDS subjects with that recorded in a sample of paired fluent control subjects. RESULTS: Subjects with developmental stuttering had normal MMN to simple tone contrasts but a significant supratemporal left-lateralized enhancement of this electrophysiologic response to phonetic contrasts. In addition, the enhanced MMN correlated positively with speech disfluency as self-rated by the subjects. CONCLUSIONS: Individuals with persistent developmental stuttering have abnormal permanent traces for speech sounds, and their abnormal speech sound representation may underlie their speech disorder. The link between abnormal speech neural traces of the auditory cortex and speech disfluency supports the relevance of speech perception mechanisms to speech production.

Acoustic Stimulation↗
PubMed2005

Auditory event-related potentials as a function of abstract change magnitude.

Event-related potentials were recorded in healthy volunteers to test the accuracy of the human brain to extract, preattentively, auditory abstract rules. The abstract rule was determined by the frequency relationship between two pure tones forming a pair. The standard pairs had identical tone frequency, whereas the deviant pairs had the second tone two, four, six or eight musical steps higher or lower in frequency than the first one. All abstract changes elicited mismatch negativity, which was not affected by the magnitude of change. However, the subsequent P3a increased as a function of the magnitude of the abstract change. These results suggest that mismatch negativity detects violations of abstract rules, and the amount of violation is analyzed in subsequent stages of auditory processing.

Acoustic Stimulation↗