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Marc M Van Hulle

Publications and source records attributed to Marc M Van Hulle.

6 recordsLinked to original sources

A novel method for determining the nature of time series.

The delay vector variance (DVV) method, which analyzes the nature of a time series with respect to the prevalence of deterministic or stochastic components, is introduced. Due to the standardization within the DVV method, it is possible both to statistically test for the presence of nonlinearities in a time series, and to visually inspect the results in a DVV scatter diagram. This approach is convenient for interpretation as it conveys information about the linear or nonlinear nature, as well as about the prevalence of deterministic or stochastic components in the time series, thus unifying the existing approaches which deal either with only deterministic versus stochastic, or the linear versus nonlinear aspect. The results on biomedical time series, namely heart rate variability (HRV) and functional Magnetic Resonance Imaging (fMRI) time series, illustrate the applicability of the proposed DVV-method.

Algorithms↗

Indications of nonlinear structures in brain electrical activity.

The dynamical properties of electroencephalogram (EEG) segments have recently been analyzed by Andrzejak and co-workers for different recording regions and for different brain states, using the nonlinear prediction error and an estimate of the correlation dimension. In this paper, we further investigate the nonlinear properties of the EEG signals using two established nonlinear analysis methods, and introduce a "delay vector variance" (DVV) method for better characterizing a time series. The proposed DVV method is shown to enable a comprehensive characterization of the time series, allowing for a much improved classification of signal modes. This way, the analysis of Andrzejak and co-workers can be extended toward classification of different brain states. The obtained results comply with those described by Andrzejak et al., and provide complementary indications of nonlinearity in the signals.

Journal Article↗

Signal nonlinearity in fMRI: a comparison between BOLD and MION.

In this paper, we introduce a methodology for comparing the nonlinearities present in sets of time series using four different nonlinearity measures, one of which, the "delay vector variance" method, is a novel approach to the characterization of a time series. It is then applied to examine the difference in nonlinearity between functional magnetic resonance imaging (fMRI) signals that have been recorded using different contrast agents. Recently, an exogenous contrast agent, monocrystalline iron oxide particle (MION), has been introduced for fMRI, which has been shown to increase the functional sensitivity compared with the traditional blood oxygen level dependent (BOLD) technique. The resulting fMRI signals are influenced by cerebral blood volume, whereas the more traditionally recorded BOLD signals are influenced not only by cerebral blood volume, but also by the cerebral blood flow and the metabolic rate of oxygen. The proposed methodology is applied to address the question whether this difference in the number of physiological variables is reflected in a difference in the degree of nonlinearity. We therefore analyze two sets of fMRI signals, one from a BOLD and the other from a MION monkey study with similar experimental designs. In the neuroimaging context, the proposed nonlinearity analyses are different from those described in the literature, since no a priori model is assumed: rather than pinpointing the source(s) of nonlinearity, nonparametric analyses are performed on BOLD and MION fMRI signals. Furthermore, we introduce a strategy for analyzing a population of fMRI signals, rather than focusing the analysis on one signal, as is traditionally done in the domain of nonlinear signal processing. Our results show that, overall, the BOLD signals are more nonlinear in nature than the MION ones, which is in agreement with current hypotheses.

Animals↗

Joint entropy maximization in kernel-based topographic maps.

A new learning algorithm for kernel-based topographic map formation is introduced. The kernel parameters are adjusted individually so as to maximize the joint entropy of the kernel outputs. This is done by maximizing the differential entropies of the individual kernel outputs, given that the map's output redundancy, due to the kernel overlap, needs to be minimized. The latter is achieved by minimizing the mutual information between the kernel outputs. As a kernel, the (radial) incomplete gamma distribution is taken since, for a gaussian input density, the differential entropy of the kernel output will be maximal. Since the theoretically optimal joint entropy performance can be derived for the case of nonoverlapping gaussian mixture densities, a new clustering algorithm is suggested that uses this optimum as its "null" distribution. Finally, it is shown that the learning algorithm is similar to one that performs stochastic gradient descent on the Kullback-Leibler divergence for a heteroskedastic gaussian mixture density model.

Algorithms↗

Kernel-based topographic map formation achieved with an information-theoretic approach.

A new information-theoretic learning algorithm is introduced for kernel-based topographic map formation. The kernels are allowed to overlap and move freely in the input space, and to have differing kernel ranges. We start with Linsker's infomax principle and observe that it cannot be readily extended to our case, exactly due to the presence of kernels. We then consider Bell and Sejnowski's generalization of Linsker's infomax principle, which suggests differential entropy maximization, and add a second component to be optimized, namely, mutual information minimization between the kernel outputs, in order to take into account the kernel overlap, and thus the topographic map's output redundancy. The result is joint entropy maximization of the kernel outputs, which we adopt as our learning criterion. We derive a learning algorithm and verify its performance both for a synthetic example, for which the optimal result can be derived analytically, and for a classic real-world example.

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