PubMed Health⌕ Search

Biomedical subjects

Marco Mazzocchi

Publications and source records attributed to Marco Mazzocchi.

10 recordsLinked to original sources
PubMed2005

Prospective study on Trilucent soybean oil-filled breast prosthesis.

BACKGROUND: The use of Trilucent breast implants dates back to 1995. These implants were produced in an attempt to overcome the perceived shortcomings of other implants filled with saline and silicone gel. The filler material, which was derived from soybean oil, was said to be biodegradable and biocompatible. When this prosthesis was subsequently found to be prone to rapid aging and rupture of the silicone shell, the company that manufactured this implant decided to withdraw it from the market and offered to remove or replace all Trilucent prostheses. METHODS: The authors present a clinical study of the Trilucent implant in which 36 patients received a total of 63 implants and 33 patients had 58 implants removed. The authors also examined the implant shell of the removed prostheses to investigate the possible cause of silicone implant aging and rupture. RESULTS: Each of the implants removed was carefully inspected visually, and samples of the implant shell were analyzed by scanning electron microscopy. All the implants removed had a very bizarre appearance; they were variegated in color, with shades of yellow and brown, and were studded with whitish yellow nodules whose number grew in proportion to the time the prosthesis was implanted. Scanning electron microscopic analysis of the implant shell revealed a heterogeneous inner surface of the implant together with fissures and globoid deposits on the cut surface. CONCLUSIONS: The authors' findings on Trilucent implants are similar to those reported in previously published studies for other types of breast implants for the first 2 years after implantation, after which a progressive, rapid deterioration was observed.

Adult↗
PubMed2005

Merkel cell carcinoma in the orbitopalpebral region.

Trabecular carcinoma is a rare cutaneous neuroendocrine carcinoma that probably originates from the Merkel cells that are usually found in the basal layer of the epidermis. The treatment of Merkel cell carcinoma is controversial and there is no specific therapeutic protocol because of the small number of cases that have been published. The procedures used to treat Merkel cell carcinoma must be tailored to minimise morbidity while maximising survival. Because the condition is so rare and difficult to diagnose and treat, we report three cases of orbitopalpebral tumours that confirm the local and regional aggressiveness and the high metastatic potential of this tumour.

Aged↗
PubMed2004

Mammary compliance: an objective measurement of capsular contracture.

Capsular contracture is the most unpredictable complication after mammary augmentation. It presents an uncertain evolution, and is one of the most difficulty complications to treat. Evaluation of this condition usually was relegated to the surgeon's judgment, but currently there are three methods for measuring capsular contracture: palpation, applanation tonometry, and measure of mammary compliance. A prospective study was conducted to evaluate the different methods for managing capsular contracture. Particular attention was paid to the measure mammary compliance with a new device: the Anton Paar Mammacompliance system. This study found a good match between clinical and objective measurements, and also between the measure of applanation tonometry and the measure of mammary compliance. The Anton Paar Mammacompliance system seems to be effective in eliminating the descriptive part and keeping to the measurements and objective data. It is easily reproducible in the various check ups. It permits objective assessment for the measure of capsular contracture.

Adult↗
PubMed2002

Reconstruction of a natural-looking umbilicus.

Based on the assumption that the umbilicus is a wound that has healed by second intention, we describe a method of reconstruction. The procedure consists of complete resection of the umbilical scar and its reconstruction by a linear incision at the site of the new umbilicus and inversion of the skin hedges, which are sutured to the linea alba leaving a 1 cm space between the skin borders to cause secondary wound healing. This procedure provides a natural-looking umbilicus. It is easy and quick to do, and can be used for reconstruction after abdominoplasty, excision of a naevus, or when the umbilicus has been removed during a previous xiphopubic incision.

Adult↗
PubMedDate not supplied

Changes over time in mammary compliance values after breast augmentation.

Capsular contracture is the most troublesome and distressing complication after breast augmentation for both the surgeon and patient. The etiology of capsular contracture remains unclear. Clinical treatment for this complication is based on the surgeon's evaluation, the condition of the breast, and a number of other factors. In a previous study, the authors investigated whether measurement of mammary compliance as a means of assessing capsular contracture was comparable with other methods described for the assessment of capsular contracture. The purpose of this study was to evaluate whether capsular contracture varies significantly over time. A prospective study was performed to measure mammary compliance in 60 female patients who received a total of 120 implants between 2000 and 2002. The implants used were anatomic prostheses filled with cohesive silicone gel and round double-lumen prostheses filled with silicone gel and saline solution. All the patients were followed up for at least 2 years. Statistical analysis of the data also was performed to assess significance. The results showed a general trend in mammary compliance values over time.

Adolescent↗
PubMedDate not supplied

Conservative management of local Mycobacterium chelonae infection after combined liposuction and lipofilling.

A case of Mycobacterium chelonae infection in the buttock after combined liposuction and lipoinjection is presented. The real possibility of contamination from operating room equipment was the potential etiologic factor of this infection. The clinical presentation of the disease was typical. The difficulty confirming the diagnosis was solved by specific culturing techniques. Successful treatment with limited debridement and irrigation combined with prolonged specific antibiotic therapy effected a long-term cure.

Adipose Tissue↗
PubMedDate not supplied

The effects of zafirlukast on capsular contracture: preliminary report.

Capsular contracture after breast augmentation is a distressing, troublesome event both for the patient and the surgeon. Fibrosis transforms the prosthesis into a hardened sphere, turning the initially satisfactory cosmetic result into a deformed mass. Treatment for capsular contracture can be either surgical, consisting of capsulotomy or capsulectomy with implant replacement, or pharmacologic, consisting of intracapsular instillation of steroids and antibiotics. The success rates for both types of treatment vary. Although capsular contracture is a multifactorial process, one common denominator in the successful treatment of this complication is believed to be the abatement of inflammation. Leukotriene antagonists have emerged recently as effective prophylactic agents for reactive airway diseases. Anecdotal reports have indicated that zafirlukast and montelukast effectively reverse capsular contracture. The authors investigated whether capsular contracture varies significantly over time after zafirlukast therapy by studying 20 women who had breast prostheses implanted and then experienced the development of capsular contracture. The results suggest that capsular contracture responds favorably to treatment with zafirlukast. The findings indicate that zafirlukast may reduce pain and breast capsule distortion for patients with long-standing contracture who either are not surgical candidates or do not wish to undergo surgery.

Adult↗
PubMedDate not supplied

Extrarenal malignant rhabdoid tumour of the heel--a case report.

Malignant rhabdoid tumour is a rare soft-tissue neoplasm that occurs in children and young adults. Cases have involved numerous extrarenal sites, including the thymus, liver, paravertebral region, central nervous system, heart, prostate, pelvis, chest wall, extremities, as well as soft tissues. Given their highly aggressive nature, early diagnosis of rhabdoid tumours is essential; indeed, survival times after initial presentation are typically in the range of months rather than years. The low incidence of rhabdoid tumours and confusion between this type of tumour and other tumours has precluded the collection of adequate data on its clinical presentation and there is no specific therapeutic protocol. Owing to the rarity of this condition and the difficulties encountered in its diagnosis and treatment, we report the case of a malignant tumour with rhabdoid-like features in the foot that confirms the local aggressiveness and the high metastatic potential of this type of tumour.

Adult↗
PubMedDate not supplied

Giant fibrolipoma in the leg--a case report.

Lipomas are the most common benign tumors of the mesenchyme; they are composed of mature lipocytes. Benign fatty tumours can arise in any location in which fat is present. Most patients affected by such tumours are in their fifth or sixth decade of life. Only rarely are children affected. Lipomas may be single or multiple. Multiple lipomas are more common in women; many are seen in a familial setting. For a lipoma to be referred to as "giant", the lesion should be at least 10 cm in diameter or weigh a minimum of 1000 g. When very close to vital structures, giant lipomas may, on account of their excessive size, cause functional limitations, such as lymphedema, pain or nerve compression syndromes. Owing to the peculiarity of this condition and the difficulties encountered in its diagnosis and treatment, a case of a giant fibrolipoma in the leg is reported. A 48-year-old woman presented with an enlarging, soft, noduled mass on the right ankle and in the lower third of the right leg and heel; it was decided to remove the mass with all the overlying epidermis and to repair the resulting lesion first with fibroblast culture and subsequently with a meshed dermo-epidermal graft. One year after surgery, both the local and the general condition of the patient were good and there were no signs of recurrence.

Female↗