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Biomedical subjects

Marcus Vetter

Publications and source records attributed to Marcus Vetter.

5 recordsLinked to original sources

Effect of 3D ultrasound probes on the accuracy of electromagnetic tracking systems.

In the last few years, 3D ultrasound probes have became readily available. New fields of image-guided surgery applications are opened by attaching small electromagnetic position sensors to 3D ultrasound probes. However, nothing is known about the distortions caused by 3D ultrasound probes regarding electromagnetic sensors. Several trials were performed to investigate error-proneness of state-of-the-art electromagnetic tracking systems when used in combination with 3D ultrasound probes. It was found that 3D ultrasound probes do distort electromagnetic sensors more than 2D probes do. When attaching electromagnetic sensors to 3D probes, maximum errors of 5 mm up to 119 mm occur. The distortion strongly depends on the electromagnetic technology as well on the probe technology used. Thus, for 3D ultrasound-guided applications using electromagnetic tracking technology, the interference of ultrasound probes and electromagnetic sensors have to be checked carefully.

Electricity↗

The medical imaging interaction toolkit.

Thoroughly designed, open-source toolkits emerge to boost progress in medical imaging. The Insight Toolkit (ITK) provides this for the algorithmic scope of medical imaging, especially for segmentation and registration. But medical imaging algorithms have to be clinically applied to be useful, which additionally requires visualization and interaction. The Visualization Toolkit (VTK) has powerful visualization capabilities, but only low-level support for interaction. In this paper, we present the Medical Imaging Interaction Toolkit (MITK). The goal of MITK is to significantly reduce the effort required to construct specifically tailored, interactive applications for medical image analysis. MITK allows an easy combination of algorithms developed by ITK with visualizations created by VTK and extends these two toolkits with those features, which are outside the scope of both. MITK adds support for complex interactions with multiple states as well as undo-capabilities, a very important prerequisite for convenient user interfaces. Furthermore, MITK facilitates the realization of multiple, different views of the same data (as a multiplanar reconstruction and a 3D rendering) and supports the visualization of 3D+t data, whereas VTK is only designed to create one kind of view of 2D or 3D data. MITK reuses virtually everything from ITK and VTK. Thus, it is not at all a competitor to ITK or VTK, but an extension, which eases the combination of both and adds the features required for interactive, convenient to use medical imaging software. MITK is an open-source project (www.mitk.org).

Algorithms↗

Treatment of painful vertebral fractures by kyphoplasty in patients with primary osteoporosis: a prospective nonrandomized controlled study.

UNLABELLED: This study investigates the effects of kyphoplasty on pain and mobility in patients with osteoporosis and painful vertebral fractures compared with conventional medical management. INTRODUCTION: Pharmacological treatment of patients with primary osteoporosis does not prevent pain and impaired activity of patients with painful vertebral fractures. Therefore, we evaluated the clinical outcome after kyphoplasty in patients with vertebral fractures and associated chronic pain for >12 months. MATERIALS AND METHODS: Sixty patients with primary osteoporosis and painful vertebral fractures presenting for >12 months were included in this prospective, nonrandomized controlled study. Twenty-four hours before performing kyphoplasty, the patients self-determined their inclusion into the kyphoplasty or control group so that 40 patients were treated with kyphoplasty, whereas 20 served as controls. This study assessed changes in radiomorphology, pain visual analog scale (VAS) score, daily activities (European Vertebral Osteoporosis Study [EVOS] score), number of new vertebral fractures, and health care use. Outcomes were assessed before treatment and at 3 and 6 months of follow-up. All patients received standard medical treatment (1g calcium, 1000 IE vitamin D(3), standard dose of oral aminobisphosphonate, pain medication, physical therapy). RESULTS: Kyphoplasty increased midline vertebral height of the treated vertebral bodies by 12.1%, whereas in the control group, vertebral height decreased by 8.2% (p = 0.001). Augmentation and internal stabilization by kyphoplasty resulted in a reduction of back pain. VAS pain scores improved in the kyphoplasty group from 26.2 +/- 2 to 44.2 +/- 3.3 (SD; p = 0.007) and in the control group from 33.6 +/- 4.1 to 35.6 +/- 4.1 (not significant), whereas the EVOS score increased in the kyphoplasty group from 43.8 +/- 2.4 to 54.5 +/- 2.7 (p = 0.031) and in the control group from 39.8 +/- 4.5 to 43.8 +/- 4.6 (not significant). The number of back pain-related doctor visits within the 6-month follow-up period decreased significantly after kyphoplasty compared with controls: mean of 3.3 visits/patient in the kyphoplasty group and a mean of 8.6 visits/patient in the control group (p = 0.0147). CONCLUSIONS: The results of this study show significantly increased vertebral height, reduced pain, and improved mobility in patients after kyphoplasty. Kyphoplasty performed in appropriately selected osteoporotic patients with painful vertebral fractures is a promising addition to current medical treatment.

Adult↗

ROPES: a semiautomated segmentation method for accelerated analysis of three-dimensional echocardiographic data.

Echocardiography (cardiac ultrasound) is today the predominant technique for quantitative assessment of cardiac function and valvular heart lesions. Segmentation of cardiac structures is required to determine many important diagnostic parameters. As the heart is a moving organ, reliable information can be obtained only from three-dimensional (3-D) data over time (3-D + time = 4-D). Due to their size, the resulting four-dimensional (4-D) data sets are not reasonably accessible to simple manual segmentation methods. Automatic segmentation often yields unsatisfactory results in a clinical environment, especially for ultrasonic images. We describe a semiautomated segmentation algorithm (ROPES) that is able to greatly reduce the time necessary for user interaction and its application to extract various parameters from 4-D echocardiographic data. After searching for candidate contour points, which have to fulfill a multiscale edge criterion, the candidates are connected by minimizing a cost function to line segments that then are connected to form a closed contour. The contour is automatically checked for plausibility. If necessary, two correction methods that can also be used interactively are applied (fitting of other line segments into the contour and searching for additional candidates with a relaxed criterion). The method is validated using in vivo transesophageal echocardiographic data sets.

Algorithms↗

Evaluation of visualization techniques for image-guided navigation in liver surgery.

A substantial component of an image-guided surgery system (IGSS) is the kind of three-dimensional (3D) presentation to the surgeon because the visual depth perception of the complex anatomy is of significant relevance for orientation. Therefore, we examined in this contribution four different visualization techniques, which were evaluated by eight surgeons. The IGSS developed by our group supports the intraoperative orientation of the surgeon by depicting a visualization of the spatially tracked surgical instruments with respect to intrahepatic vessels that have to be conserved vitally, the tumor, and preoperatively calculated resection planes. In the prelimenary trial presented here we examined the human ability to percept an intraoperative virtual scene and to solve given navigation tasks. The focus of the experiments was to measure the ability of eight surgeons to orientate intrahepaticaly and to transfer the percepted spatial relation to movements in real space. An autostereoscopic visualization with a prism-based display yielded that the navigation can be performed faster and more accurately than with the other visualization techniques.

Anatomy, Regional↗