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Marek Synder

Publications and source records attributed to Marek Synder.

23 records · Page 2Linked to original sources
PubMed2002

[Gel derived bioactive ceramic as bone substitute--an in vivo study].

The paper presents the histopathological and radiological study performed on a series of male, mixed-race rabbits. All rabbits had a 20 x 4 x 4 mm-bone fragment extracted from the radial bone according to a modified technique by Scmitt and Weller. In the right radius bone the bone defect was filled with approximately 0.5 cm3 bioglass S2. In the left rius, which served as control, allogenic bone graft (the size of the defect) collected from the tibia and femur was implanted. Rabbits were sacrificed 3, 6 and 12 weeks after the procedure and histopathological and radiological studies were performed. These studies revealed a heterogeneous increase of new bone regeneration in all three phases of the study. The S2 biomaterial both stimulated and accelerated bone regeneration in the rabbits.

Animals↗
PubMedDate not supplied

Leg length discrepancy in Legg-Calve-Perthes disease.

The purpose of this study was to determine the incidence of the leg length discrepancy (LLD) in Legg-Calve-Perthes disease and whether there is any correlation between LLD and age at onset, gender, type of treatment, and severity of disease. The study population consisted of 261 patients with unilateral involvement who had reached skeletal maturity at last follow-up. All hips were treated by containment methods (bed rest and traction in abduction, Petri cast, brace, varus osteotomy, Salter osteotomy, and shelf acetabuloplasty). The late results were classified according to the Stulberg classification. LLD was found in 33 patients and ranged from 1 to 5.2 cm (average 2.51 cm). The limb shortening was observed in Herring group B (average 2.18 cm) and C (average 2.82 cm) and was statistically significant more common in group C. The statistical analysis revealed no statistical difference between the age at onset, sex, and type of treatment with regard to LLD; nevertheless, patients in Herring group C with LLD were younger than patients in group B, and LLD was seen more often after varus osteotomy. The amount of residual shortening of the affected limb in Legg-Calve-Perthes disease at the end of skeletal growth seems to depend on the extent of involvement and the presence of a growth arrest. A varus osteotomy produces more significant shortening than other methods of treatments. The age at the onset of symptoms and sex do not influence the amount of LLD, but early onset of the disease can result in more severe limb shortening.

Adolescent↗
PubMedDate not supplied

Lateral growth disturbances of the capital femoral epiphysis after nonoperative treatment of late developmental dislocation of the hip: thirty-five cases followed to skeletal maturity.

The purpose of this study was to evaluate the effect of type 2 growth disturbances in the developing hip and compare it with other treated hips without evidence of growth arrest. Radiographic data of 117 children (155 hips) with late developmental dislocation of the hip treated by closed reduction at an average age of 14.9 months and followed to skeletal maturity were retrospectively reviewed. Depending on the presence of lateral growth disturbances, our patients were divided into 2 groups similar with regard to age and treatment methods. Lateral physeal arrest was evident at an average age of 8.9 years in 23% of these hips. Seventy-six percent of these hips with type 2 avascular necrosis were classified as Severin classes 1 and 2. One quarter of them had no deformity of femoral head, 8 had deformity of 2 mm or less, and 18 more than 2 mm. There was no statistical difference in satisfactory and unsatisfactory results or most parameters describing the acetabulum between the 2 groups. Lateral tilting of the proximal femoral epiphysis in most cases does not affect final radiologic results. It is a mild form of avascular necrosis and indications for secondary operative procedures are mostly related to natural history of the disease rather than to lateral physeal arrest.

Adolescent↗
PubMedDate not supplied

The role of the acetabulum in Perthes disease.

The purpose of this study is to evaluate the changes in the shape of acetabulum from the onset of the disease to the skeletal maturity in Legg-Calvé-Perthes disease. The study population consisted of 243 patients with unilateral involvement who had reached skeletal maturity at last follow-up. All hips were treated by containment methods (which included bed rest and traction in abduction, Petri cast, brace, varus osteotomy, Salter osteotomy, and shelf acetabuloplasty). Necrosis of the femoral head was estimated according to the lateral pillar classification and late results according to the Stulberg classification. Changes in the shape of the acetabulum were divided into 3 groups: type I-normal, concave lateral acetabulum margin; type II-flat, horizontal lateral acetabulum margin; and type III-convex, sloping acetabular margin. Roentgenograms performed during the fragmentation stage revealed type I changes in 78 (32.1%) hips, type II in 136 (55.7%), and type III in 29 (12.2%). At the last follow-up, there were type I changes in 124 (51.2%) hips, type II in 81 (33.5%), and type III in 38 (15.3%). The statistical analysis revealed no significant statistical difference between the age at the onset and gender with regard to acetabular changes. There was significant statistical correlation between the lateral pillar classification, subluxation of the femoral head, the range of hip abduction, and the Stulberg classification with regard to acetabular changes. A type III was statistically associated with lateral pillar classification group C, major subluxation of the femoral head, limited hip abduction, and in Stulberg group 3, 4, or 5. Only surgical methods of treatment improved the acetabular shape at the last follow-up (P<0.05). In our opinion, the lateral acetabulum shape plays a very important role during the remodeling of the deformed proximal femoral epiphysis.

Acetabulum↗