PubMed Health⌕ Search

Biomedical subjects

Marek Wroński

Publications and source records attributed to Marek Wroński.

5 recordsLinked to original sources

[Recurrent lower gastrointestinal bleeding due to a gastrointestinal stromal tumor (GIST) of the small intestine].

Gastrointestinal bleeding is a common cause of hospitalisation. In most patients, the origin and location of bleeding can be established in routine endoscopic and radiological examinations. The undiagnosed cases of so-called gastrointestinal bleeding of unknown origin require more sophisticated diagnostic methods. We present a case of 35-year old man with recurrent gastrointestinal bleeding due to a gastrointestinal stromal tumor of the jejunum that was revealed in the visceral angiography.

Adult↗

[Late malignant melanoma metastases within the abdominal cavity imitating clinically and pathologically a gastrointestinal stromal tumor].

Melanoma is a malignant skin neoplasm that often metastasizes within the abdominal cavity. Melanoma metastases can develop even many years after the primary treatment. Clinical course, microscopic histology, and immunohistochemical profile of melanoma may imitate a gastrointestinal stromal tumor (GIST). We report a case of 55-year old man with a history of melanoma treatment 23 years earlier who presented with recurrent duodenal bleeding from a neoplastic tumor that was primarily diagnosed as GIST The histology of the tumor was reviewed and confirmed the diagnosis of metastatic melanoma.

Diagnosis, Differential↗

[Seminoma metastases as a retroperitoneal space tumor].

This is a case report of a testicular tumor, probably seminoma, presenting a retroperitoneal mass. The patient underwent surgical removal of tumor and the possibility of testicular tumor on the basis of histological examination was assumed. However, the histological examination of the testicle did not confirm the diagnosis of seminoma. The patient did not give consent for adjuvant chemotherapy. He has been remaining under clinical follow-up.

Humans↗

[Fournier's gangrene in non-resectable colorectal carcinoma].

Fournier's gangrene is a necrotizing fasciitis of the genitalia and perineum. Primary inflammatory focus is usually located in the genitourinary tract, skin or anorectum. The gangrene is caused by a mixed bacterial flora. The management is based on surgical debridement, drainage and antibiotics. Despite of adequate treatment mortality is approximately 20%. We present a case of 65 year-old male with a non-resectable rectal carcinoma who developed Fournier's gangrene after a palliative operation because of intestinal obstruction. Several excisions of the necrotic tissues were performed resulting in significant local improvement. The patient died of disseminated carcinoma a few weeks after the last debridement procedure.

Aged↗

[Fournier's gangrene].

Fournier's gangrene is a necrotizing fasciitis of the genital and scrotal region due to infectious process. The gangrene is rare. Most cases are diagnosed in elderly patients with immunodeficiency, especially in diabetics or alcoholics. Currently a primary infection focus can be revealed in about 95% cases. The nidus is usually located in the genitourinary tract, lower gastrointestinal tract or skin. Fournier's gangrene is a mixed infection caused by both aerobic and anaerobic bacterial flora. The development and progression of the gangrene is often fulminating and can rapidly cause multiple organ failure and death. Early surgical debridement of necrotic tissues and antibiotics are fundamental in the treatment of Fournier's gangrene. Despite of advanced management mortality is still high and averages 20-30%.

Disease Progression↗