Characterisation of Nine New HLA Alleles.
Nine novel HLA alleles were detected during the HLA typing process.
Biomedical subjects
Publications and source records attributed to Maria Loginova.
Nine novel HLA alleles were detected during the HLA typing process.
The novel HLA-A*25:95 allele differs from HLA-A*25:01:01:01 by one nucleotide substitution in exon 2.
Seven HLA class II alleles were detected and confirmed.
We identified seven novel HLA class I alleles by NGS.
Four new HLA-B*44 alleles characterised by Next Generation Sequencing, HLA-B*44:431Q, -B*44:432Q, -B*44:433 and -B*44:434.
The sequences of HLA-B*07:62:02 and HLA-C*07:02:165 alleles are reported.
Three novel HLA-DRB1 alleles were identified during routine next generation sequencing.
Two novel HLA-DQB1*03 alleles, HLA-DQB1*03:581 and HLA-DQB1*03:582, have nonsynonymous mutations in exon 2 and exon 3, respectively.
The novel HLA-B*35:01:86 and HLA-DRB1*15:243 alleles were detected during the HLA typing process.
Three HLA-B and three HLA-C novel alleles detected by next-generation sequencing.
HLA-DQB1*05:367 differs from HLA-DQB1*05:01:01:01 by one nucleotide substitution in codon 7 in exon 2.
Identification of eight novel HLA-DRB1 and HLA-DQB1 alleles by next-generation sequencing.