Biomedical subjects

Maria Severin

Publications and source records attributed to Maria Severin.

3 recordsLinked to original sources

PubMed2004

Contact lens, hyperopia and endothelial changes. A case report.

INTRODUCTION: We report on a 62-year-old healthy woman who suffered from bilateral predescemetic opacities, where the underlying disorder could not be identified. She had bilateral keratopathy with corneal edema, a diffuse predescemetic avascular haze and deszemetic folds. Because of high hyperopia (right +7.50/left +7.75) she weared soft contact lenses for years. METHODS: Removal of contact lenses. Treatment with local steroids and tear substitutes. RESULTS: One year after cessation of contact lenses VA recovered from RE 0.3/LE 0.1 to 0.8/0.63, the deep stromal opacity cleared up, the corneal edema recessed slightly. DISCUSSION: The differential diagnosis concludes either a pure contact lens change that is not completely reversible or a possible posterior polymorphous dystrophy that worsens with long-term contact lens wear and improves on cessation.

Contact Lenses, Hydrophilic↗

PubMed2003

A case of angle-closure glaucoma, cataract, nanophthalmos and spherophakia in oculo-dento-digital syndrome.

BACKGROUND: We report a new case of oculo-dento-digital syndrome. METHODS: Case report. RESULTS: We saw a 34-year-old women with oculo-dento-digital syndrome. Visual acuity was no perception of light (RE) and 1/35 (LE). Biomicroscopy revealed a flat anterior chamber and an advanced cataract. The intraocular pressure (IOP) was 60 mmHg in both eyes. Ultrasonographic biomicroscopy demonstrated a closed chamber angle in both eyes. Measurements of the axial length and of the diameter of the lens were 18.7 mm/6.0 mm for the RE and 18.7 mm/5.8 mm for the LE respectively. In the time following we conducted a cyclodestructive procedure in the RE and a cataract extraction with implantation of an intraocular lens in the LE. This led to a considerable reduction of the IOP in the RE and combined with local therapy to IOP regulation in the LE. CONCLUSION: In this patient nanophthalmos, cataract and spherophakia led to angle-closure glaucoma in both eyes. We recommend early monitoring of IOP, axial length and lens diameter. This case demonstrates that an early cataract extraction might beneficially influence the natural course of the disease.

Abnormalities, Multiple↗

PubMedDate not supplied

Treatment of granular dystrophy with soft contact lenses.

PURPOSE: To prevent recurrence of granular dystrophy by treatment with soft contact lenses. METHODS: After penetrating keratoplasty, a soft contact lens was fitted in a 61-year-old woman patient with granular corneal dystrophy. The lens was worn continuously for 53 months. RESULTS: No recurrence was observed. However, the other eye, which was operated on first and not treated with a contact lens, showed severe recurrence of the underlying disease, with granular deposits in the stroma. CONCLUSIONS: Fitting of a soft contact lens should be considered in this disease after penetrating keratoplasty.

Contact Lenses, Hydrophilic↗