Biomedical subjects

Marianne Ors

Publications and source records attributed to Marianne Ors.

4 recordsLinked to original sources

PubMed2005

SPECT findings in children with specific language impairment.

Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous neurodevelopment with deviant hemispheric lateralization as an important factor in the aetiology of SLI. They also point to the role of subcortical structures in language impairment in childhood. Earlier focus on cortical structures in SLI research needs to be widened to include subcortical regions as well.

Adolescent↗

PubMed2005

Interdisciplinary and prospective studies necessary to increase insight into developmental language disorders.

UNLABELLED: The study of developmental language disorders is discussed from an interdisciplinary perspective. It is argued that retrospective studies have provided valuable information on developmental language disorders that needs to be integrated into a theoretical model capable of capturing the basic mechanisms of language development. CONCLUSION: It is concluded that interdisciplinary and prospective studies and theoretical work are necessary to increase insight into developmental language disorders.

Child↗

PubMed2002

Auditory event-related brain potentials in children with specific language impairment.

Event-related brain potentials evoked by tone and speech stimuli were recorded in ten children with specific language impairment and a control group. The patient group showed prolonged P3 latencies in both tasks compared with the controls and smaller P3 amplitude in the speech task. There were no group differences concerning the N1-P2 components. The findings indicate that the children with language impairment showed signs of deficient late-stage auditory perceptual processing whereas the earlier sensory stages as indexed by the N1 were no different from the controls. The results are further discussed within the framework of context updating in working memory.

Adolescent↗

PubMed2002

Auditory event-related brain potentials in parents of children with specific language impairment.

Auditory event-related brain potentials evoked in response to tone stimuli and to speech stimuli were recorded in a group of parents of children with specific language-impairment and a group of parents of normally speaking children. The parents of the language-impaired children showed longer P3 latencies than the parental control group in the speech task requiring a phonological discrimination, but did not differ from the controls in the linguistically non-demanding tone discrimination task. The longer P3 latency was associated with a positive parental history of language delay. There were no group differences concerning the N1 component in any of the tasks. The findings indicate that parents of children with specific language impairment show signs of deficient late-stage perceptual higher order linguistic processing, whereas the earlier central sensory detection stage of the phonological information is no different from the controls. Our observations are particularly interesting with regard to a study of the children of these two parental groups, where the language-impaired children showed longer P3 latencies than controls in both a tone task and a speech task, whereas there were no differences between the children concerning the N1 component. We propose that deficient late-stage auditory higher order perceptual processing as indexed by the longer P3 latency to speech stimuli observed both in children with specific language-impairment and in their parents may represent a constitutional trait, contributing to the language acquisition difficulties in these children.

Adult↗