Biomedical subjects

Marjeta Misigoj-Duraković

Publications and source records attributed to Marjeta Misigoj-Duraković.

9 recordsLinked to original sources

PubMed2006

Dispersion of the corrected QT and JT interval in the electrocardiogram of alcoholic patients.

BACKGROUND: The aim of this study was to analyze the corrected QT interval (QTc), its dispersion (QTcd), and the QT interval index (QTcI) and to compare it with the corrected JT interval (JTc), its dispersion (JTcd), and the JT interval index (JTcI) in long-term alcoholic users, by investigating the ventricular activation until the completion of repolarization. METHODS: The study of ECGs was performed on a selected group of 49 male white alcoholic patients, mean age 53.51+/-4.78 years. The control group was pair-matched. The analysis of ECGs was performed according to the Minnesota Code, and Bazett's formula gave the values of the corrected QT interval and JT interval. RESULTS: The results of the descriptive statistics in the group of alcoholics showed a range of the QTcd of 12.0 to 103.0 milliseconds, mean 44.2+/-18.6 milliseconds, compared with 5.0 to 68.0 milliseconds, mean 23.8+/-11.1 milliseconds, in the control group (p < 0.0001). The range of JTcd in the alcoholic patients was 11.0 to 88.0 milliseconds, mean 43.0+/-18.3 milliseconds, compared with 5.0 to 66.0 milliseconds, mean 22.8+/-12.1 milliseconds, in the control group (p < 0.0001). The QTc from 422.0 to 480.0 milliseconds was obtained in 69.4% of the alcoholic patients and 32.6% of the controls. The QTc over 480.0 milliseconds was found in 24.5% of the alcoholic patients, but was not recorded among the controls at all (p < 0.0001). The QTcd over 50.0 milliseconds was registered in 34.7% of the alcoholic patients, while in the controls a QTcd above 50 milliseconds was found in 2.0% (p < 0.0001). The mean values of QT were markedly higher in the alcoholic patients (p < 0.01) than in the controls. The same was the case with the values of QTd, QT(I), QTcd, and QTcI (p < 0.0001). Also, the mean values of JTd, JT(I), JTc, JTcd, and JTcI were significantly higher in the alcoholic patients than in the controls (p < 0.0001). The mean value of JT, although higher in the alcoholic patients, did not significantly differ between the examined groups (p=0.1002). The odds ratio estimated for prolonged QTc and for enlarged QTcd in the alcoholics versus the controls was 31.625 and 25.500 (p < 0.0001), respectively. CONCLUSIONS: Persons who consume various alcoholic beverages excessively and for a long time have significantly higher dispersions of the QTc and JTc, intervals and they have a significantly higher estimation of relative risk for the prolonged QTc interval and higher QTc dispersion than the control group, i.e., higher risk of arrhythmias.

Alcoholism↗

PubMed2006

Does chronological age reduce working ability?

Definitions of so-called older age often are based on a chronological age of 65 years and over, although by some authors aging is the process that starts after the 30th year of life. At the beginning occur changes in the organ functions, followed by anatomical changes as well. Some organs age faster, some slower. For example, kidneys decrease for one third, lungs do not change, liver shrinks a little, prostate increases twice. In some cross-sectional studies, muscle mass in men aged 65 is on average 12 kg less than in the so-called middle age, and in women it is approximately 5 kg less. In the heart the amount of connective tissue increases, lipofuscin is deposited in cardiac muscle, the strength of which is decreasing. In the respiratory tract the number of pathways cilia decreases, along with the alveolar surface, muscles involved in breathing change, lung elasticity is also diminished. But, in regard with the previous body capacity, "physiological aging" can be divided into three types of elderly: the "older" elderly have the highest functional capacity of 2-3 MET (MET--metabolic unit, i.e. the oxygen consumption of 3.5 ml/kg body mass in a minute), the "younger" elderly are the persons of older age having maximal functional capacity of 5-7 MET, while the "sport" elderly have the functional capacity of 9-10 MET, disregarding chronological age. The brain weight diminishes for approximately 7% compared to younger age. In temporal gyrus and area striata even 20-40% of cells are being lost, vacuolar and neuroaxonal degeneration occurs, lipofuscin is being accumulated. The brain blood flow, which is in normal conditions 50-60 ml/min/100 g of tissue, with the increase of biological age decreases to about 40 ml/min/100 g of tissue. However, this usually is not the consequence of biological age but of disease. A chronological age of 65 for the beginning of "elder hood" is a sociopolitical construct developed by social security systems and government organizations to decide an arbitrary age at which benefits should be paid. Thus, it neither a border nor do changes designating old age occurs exactly with that "age border". The changes in the organism during the so-called aging are individual. So, the functional capacity of an organism, both physical and intellectual, must be evaluated individually, having in mind biological age.

Aged↗

PubMed2006

Physical fitness, menstrual cycle disorders and smoking habit in Croatian National Ballet and National Folk Dance Ensembles.

The study investigated differences in morphological, motor and functional abilities between folk and ballet dancers. The sample comprised 51 female subjects: Croatian National Ballet (N=30) and Croatian National Folk Ensemble "LADO" (N=21). The data regarding menstrual cycle, menarche, number of births and smoking habit were collected and the morphological, motor and functional abilities measured. Significant correlations between the amount of fat tissue and number of births were found in both groups. Folk dancers were as tall as ballet dancers but weighted more and had a larger body frame (p<0.001). Ballet dancers were more flexible but there were no differences in absolute maximal oxygen uptake (2.65 vs. 2.35 L/min, p=0.101). Still, as the ballet dancers weighted less, their relative maximal oxygen uptake was significantly higher (37.62 vs. 50.22 mL/kg/min, p<0.001). Also, a high number of 45% of smokers among professional ballet and professional folk dancers was found.

Adult↗

PubMed2005

Fitness profile of elite Croatian female taekwondo athletes.

The aim of the study was to assess fitness profile of elite Croatian female taekwondo athletes and to determine which physical, physiological and motor characteristics differentiate mostly the successful from the less successful fighters. Thirteen national taekwondo champions were divided into two groups according to their senior international competitive achievements. Physiological characteristics, including maximal oxygen uptake (VO2max), were assessed during a continuous progressive treadmill test. The measured motor abilities included explosive and elastic leg strength, maximal strength, muscular endurance, anaerobic alactic power, agility and flexibility. Differences between the successful and less successful athletes were determined using independent t-test. Even though the differences were not statistically significant, the successful athletes had somewhat less fat (2.3%) and were taller by 5.8 cm. The successful athletes achieved significantly higher maximum running speed (15.8 +/- 0.5 versus 14.9 +/- 0. 7 km h(-1); p < 0.05), their ventilatory anaerobic threshold was significantly higher (41.4 +/- 4.1 versus 37.6 +/- 2.0 ml kg(-1) min(-1); p < 0.05) at a significantly lower heart rate (166.8 +/- 6.8 versus 171.0 +/- 8.2 beats min(-1); p < 0.05) than in the less successful athletes. Significant differences were also found in three tests of explosive power (p < 0.05), anaerobic alactic power (p < 0.01), and lateral agility (p < 0.05). The performance of taekwondo female athletes primarily depends on the anaerobic alactic power, explosive power expressed in the stretch-shortening cycle movements, agility and aerobic power.

Adolescent↗

PubMed2004

Gender differences in cardiovascular diseases risk for physical education teachers.

The aim of the study was to evaluate the level of habitual physical activity in Croatian physical education (PE) teachers, as well as the existence of some other risk factors for the development of cardiovascular diseases (CVD). The sample consisted of 191 PE teachers aged 24 to 59 years (122 men, mean age 42.6+/-8.76 and 69 women, mean age 40.3+/-8.84;p=0.09). In order to assess the level of habitual physical activity, the teachers were asked to fill in Baecke's questionnaire. The questionnaire comprises 16 items testing physical loads at work, during sport activity and during leisure time. The questionnaire also contains 8 items, each of them representing a certain cardiovascular risk factor. In comparison to average adult employed population, PE teachers have a significantly higher level of sport and leisure time activity, which could have a favorable impact on the incidence of particular risk factors, such as overweight/obesity, systolic hypertension and blood cholesterol level. This is more obvious in females PE teachers who pay more attention to the principles of healthy life style: optimal body weight regulation, low fat diet and higher amount of leisure time physical activity (significantly higher than in male teachers). Female PE teachers who have maintained their active life style decrease the risk of CVD, particularly after the age of 55. Although it is necessary to keep in mind all the limitations of a questionnaire study, this preliminary report leads to the conclusion that male PE teachers, although physically active at job, have still kept sedentary habits, often have maintained heavy smoking habits, are slightly overweight, thus minimizing the positive effects of their demanding workplace. Consequently, average male PE teachers' risk for CVD development corresponds to the risk of general male population.

Adult↗

PubMed2004

Fitness level of adult economically active population in the Republic of Croatia estimated by EUROFIT system.

The study presents the results of the EUROFIT CROATIA project that was conducted according to the instructions of Council of Europe. The aim of the study was evaluation of fitness level of the employed Croatian population. The measurements comprised EUROFIT battery of tests as well as Baecke's questionnaire for evaluation of habitual physical activity. The sample was comprised of 1628 active inhabitants, 18-60 years of age, all of who were employed and living in Croatia. The obtained results of functional, motor and morphological characteristics were presented according to the sex and age. The results shower poor aerobic capacity, high obesity indicators and low motor performance in both sexes, which pointed to the increased risk for developing many cardiovascular or musculo-skeletal diseases. The overall fitness level of Croatian population showed to be unsatisfactory and it should be improved by engagement in sports-recreational activities.

Adult↗

PubMed2004

Acute cardiovascular complications due to physical exercise in male teenagers.

Five sudden cardiac deaths in male adolescents (age 14-18 years) were detected in a 5-year period in Croatia. Two of them had been engaged in physical exercise at school, one as a professional soccer player, one in recreational swimming, and the fifth had just finished secondary school and was working at the site. All of them were autopsied and in three congenital cardiovascular diseases was found. Two had hypoplastic coronary arteries. The third had hypertrophic cardiomyopathy with interventricular wall of 40 mm. The fourth had normal heart findings including coronaries, but had bilateral pneumonia with a possible altitude (non-cardiogenic) pulmonary edema. The fifth had a chronic myopericarditis with an aneurysm of the left ventricle. All of them had not reported definite symptoms at exertion. According to this data, the death rate in adolescent males in Croatia during or after recreational physical exercise was 1/100,000 per year or 5/500,000 in five years. Thorough preparticipation medical examination including indicated laboratory tests and avoidance of heavy exertion at the time of respiratory infection might have helped to avoid some of the lethal events.

Adolescent↗

PubMed2003

Dispersion of the corrected QT interval in the electrocardiogram of the ex-prisoners of war.

The study of electrocardiograms (ECGs) was performed in a subgroup of 181 men, ex-prisoners of war with mean age 35.8+/-11.0 years and mean duration of imprisonment 164.5+/-87.1 days, chosen at random from the total sample of released prisoners (N=1458). The control group was pair-matched. The analysis of ECGs was done according to the Minnesota code, and Bazett's formula gave the values of the corrected QT interval (QT(c)). The dispersion of the QT(c) interval is determined by the difference between the longest and the shortest measured QT(c) interval in each ECG lead. The results of descriptive statistics in the group of ex-prisoners showed the range of QT(c) dispersion of 8.0-122.0 ms (mean 52.4+/-21.6 ms), while in the control group the range was 6.0-72.0 ms (mean 30.4+/-13.8 ms) (df=360, t=11.536; P<0.001). The QT(c) interval from 422.0 to 480.0 ms had 60.2% ex-prisoners and 30.4% controls, while a QT(c) interval over 480.0 ms had 19.3% ex-prisoners and 1.10% controls (P<0.0001). In the ex-prisoners group, the QT(c) dispersion over 50 ms was present in 51.4%; of those, a dispersion of 95 ms and more was found in 3.9%, while in the controls a QT(c) dispersion over 50 ms was found in 8.3%, but a dispersion of 95 ms and more was not recorded (P<0.0001). The odds ratio estimated for the prolonged QT(c) interval was 8.467 and for enlarged QT(c) dispersion it was 11.695 in the ex-prisoners versus controls (P<0.001). In conclusion, persons exposed to long-term maltreatment in detention camps have significantly greater QT(c) dispersion, as well as a higher relative risk of prolonged QT(c) interval and greater QT(c) dispersion than a control group.

Adolescent↗

PubMed2003

Morphological differences of elite Croatian soccer players according to the team position.

Team position is of extreme importance in interpretation of morphological data because there are specific demands for a specific play position. The aim of the study was the analysis of morphological characteristics and body composition of elite Croatian soccer players with respect to their team position. The measurements were performed on 57 soccer players, members of the First Croatian National League. The anthropometrical measurement encompassed 13 variables. Descriptive statistics, t-test and MANOVA were used in data processing. The goalkeepers were the tallest and the heaviest (182.9 +/- 4.3 cm; 80.1 +/- 5.1 kg), and had significantly higher amounts of body fat (20.2% goalkeepers vs. 13-15% others; p < 0.05), whereas the forwards and the midfield players were on the average about 3 cm shorter. The goalkeepers had longer legs and arms (p < 0.05), and the largest biacromial diameter (43.2 +/- 1.9 cm). The forwards were the shortest on the average (179.2 +/- 6.3 cm). The lowest values of fat tissue were found in defenders (13.9%) and midfield players (14.4%). In conclusion, the differences in morphological characteristics according to the team position were noticed only in goalkeepers, especially regarding their height, weight and the percentage of fat tissue.

Adult↗