Biomedical subjects

Mark Bishop

Publications and source records attributed to Mark Bishop.

9 recordsLinked to original sources

PubMed2006

Changes in gait kinematics and posture with the use of a front pack.

The objective of this study was to determine if posture during gait can be affected by position of the load. It was hypothesized that the front pack would result in postural changes in the gait cycle, compared to a similarly loaded backpack. Thirteen healthy adults, free of any injury, volunteered to participate in this study. Two dimensional video data were collected at 50 Hz using a MacReflex video system. A backpack and a front pack were compared using loads of 10 and 15% of body weight. Markers were placed on the ear, acromion, greater trochanter and lateral joint line of the knee, lateral malleolus and fifth metatarsophalangeal joint. Data were collected while the participants walked at 0.75 stride/s. The data were used to calculate joint angles and displacements during each gait cycle. There was a significant difference noted in angles of the hip flexion, with the backpack condition demonstrating a greater flexion in each stride than either the control or front pack. Both backpack and front pack conditions demonstrated a significant change in neck motion compared to the control condition. The results of the position analysis over time also revealed an increase in the forward head position when participants were wearing the backpack compared to either the control or the front pack condition. It was concluded that the use of a front pack results in a more upright posture in gait, when compared to a backpack carrying the same load.

Adult↗

PubMed2006

Do people with Parkinson's disease change strategy during unplanned gait termination?

In light of the movement control problems reported for patients with Parkinson's disease (PD), we examined the lower extremity control strategies used by these subjects to stop walking in planned and unplanned situations. We compared how patients with PD and age and gender-matched control subjects modulated lower extremity muscular activity and ground reaction forces during planned and unplanned stoppings. The main findings were that control subjects did not alter muscle activation from planned to unplanned stopping, relative to stance limb kinetic events; they just increased the amplitude of the response (by approximately 800%). We speculate that these data provide preliminary evidence in support of a stereotypical sequence of muscle activation for gait termination whether planned or unplanned. In contrast, subjects with PD appeared to adopt a different strategy when stopping unexpectedly compared to planned stopping. Additional data show that subjects with PD required additional steps to stop walking when stopping unexpectedly as compared to control subjects.

Aged↗

PubMed2005

Changes in distal muscle timing may contribute to slowness during sit to stand in Parkinsons disease.

OBJECTIVE: To compare patterns of muscle activation in the lower extremity and subsequent forces during sit to stand in persons with Parkinsonism. BACKGROUND: There is an interruption of the tibialis anterior/soleus interaction during forward oriented movements in some subjects with Parkinsonism, including sit to stand. This task is a major determinant of independence and 44% of those with Parkinsonism report difficulty. METHODS: 41 subjects with Parkinsonism were asked to stand up from a bench. Peak acceleration and vertical ground reaction forces, the slopes to these peaks, and the timing of events were measured. Surface electrodes were placed on tibialis anterior and soleus. RESULTS: The slower group produced force at slower rate than the fast group. The slower group spent 64% of the time taken to stand to complete the flexion-momentum phase, and the fast group spent 56%. The slower group had a larger proportion of co-contraction trials than the other groups. CONCLUSIONS: Slower subjects took longer to perform the task due to a longer time for seat off. Deficits recruiting tibialis anterior may contribute to the decreased rate of production of the acceleration forces and the longer time required for seat off. Relevance Decreased rate of rise of force is used to identify fallers in the elderly and subjects with stroke. Decreased rates of force production may therefore assist in identifying those with Parkinsonism at risk of falls. Treatment strategies designed to facilitate tibialis anterior activation may improve the functional performance of this task.

Adaptation, Physiological↗

PubMed2005

Plantar feedback contributes to the regulation of leg stiffness.

BACKGROUND: Running and hopping involve moving in a bouncing fashion during which the limbs behave as springs. The ability to alter the stiffness of these leg springs is essential to maintaining an efficient gait. Since the plantar surface of the foot is the only part of the body to encounter the ground during bipedal locomotion, it would seem logical that some aspect of the neurological functioning of the foot is responsible for transmission of information about the surface characteristics to the central nervous system, resulting in changes in leg stiffness. METHODS: Ten subjects (9 males, 1 female) participated in this experiment. Lidocaine was injected inferior and posterior to the lateral malleolus in order to achieve tibial nerve block at the level of the ankle. Subjects hopped at 2.2 Hz on a force plate while data were collected at 1000 Hz. Data were analyzed for peak force and leg stiffness and compared using a repeated measures ANOVA. FINDINGS: Tactile sensation, deep pressure sensation, and abductor hallucis activity displayed significant decreases following the injection, as did postural stability. Subjects demonstrated a significantly decreased leg stiffness after the nerve block (P<.01). INTERPRETATION: Plantar sensation has an effect on regulating leg mechanics in hopping. A loss of sensation in this region can exert a significant impact on the properties of the leg in gait, and future research should determine the specific pathways by which plantar feedback exerts this effect.

Adult↗

PubMed2004

Sural nerve evoked responses in human hip and ankle muscles while standing.

The objective of this study was to investigate the influence of background EMG, as manipulated by changes in limb loading, and electrical stimulus intensity on sural nerve evoked EMG responses in proximal hip (ipsilateral gluteus medius and contralateral adductor longus) and distal ankle (ipsilateral soleus) muscles during quiet standing. We studied 14 healthy subjects who were instructed to stand on a force platform and load the right leg to 20, 30, 60, and 80% body weight. Trains of stimuli were delivered to the right sural nerve at three different intensities (1.5, 2, and 3 perception threshold). Average evoked responses from each of the three muscles were obtained for each combination of body weight and stimulus intensity. Reflex responses were consistently seen in gluteus medius and soleus but not adductor longus. The responses in gluteus medius and soleus consisted of complex inhibitory and excitatory responses with the primary effect in gluteus medius being a short latency excitation (mean latency of 57 ms) and in soleus, a short latency inhibition-excitation (latencies of 47 and 58 ms, respectively). The amplitudes of the responses were influenced primarily by background EMG. The results demonstrate consistent sural nerve evoked EMG responses in both a hip (gluteus medius) and ankle (soleus) muscle. While the findings for soleus generally corroborate and extend previous studies, the responses observed for the lateral hip muscle have not been previously reported.

Adolescent↗

PubMed2004

The effect of velocity on the strategies used during gait termination.

The purpose of this study was to examine the changes that occur in gait termination (GT) as cadence increases. Five healthy volunteers walked at three cadences in time to a metronome under the following conditions: normal walking, planned stopping and unplanned stopping. Electromyography and force plate data were collected at 1000 Hz. Peak posterior ground reaction force (deceleration force) was greatest for the lead limb in unplanned stopping and, in general, deceleration force increased as cadence increased. Duration of muscle activity relative to the time to peak loading was unchanged by cadence and was always longest in the lead limb during planned stopping. As cadence increases, the signal to stop must occur earlier during stance phase if a person is to stop in the subsequent step.

Adult↗

PubMed2002

Does postural instability affect the initiation of human gait?

During gait initiation (GI), decoupling of the center of mass and center of pressure allows the center of mass to fall forwards. Subjects initiated gait rapidly before and after tibial nerve block of the tibial nerve. Static single limb stability, stance limb ground reaction forces, electromyogram and temporal data were measured. It was hypothesized that postural stability would decrease post-block and that this would affect the kinetic and temporal properties of GI. Subjects had significantly decreased postural stability post-block and changes in normal gait kinetics, however, no changes were noted in ground reaction forces or relative temporal data of the GI task. The finding that GI was unaffected by diminished single leg postural instability suggests that GI is a pre-programmed task.

Adaptation, Physiological↗

PubMed2002

Counterfactuals cannot count: a rejoinder to David Chalmers.

The initial argument presented herein is not significantly original--it is a simple reflection upon a notion of computation originally developed by Putnam (Putnam 1988; see also Searle, 1990) and criticised by Chalmers et al. (Chalmers, 1994; 1996a, b; see also the special issue, What is Computation?, in Minds and Machines, 4:4, November 1994). In what follows, instead of seeking to justify Putnam's conclusion that every open system implements every Finite State Automaton (FSA) and hence that psychological states of the brain cannot be functional states of a computer, I will establish the weaker result that, over a finite time window every open system implements the trace of FSA Q, as it executes program (P) on input (I). If correct the resulting bold philosophical claim is that phenomenal states--such as feelings and visual experiences--can never be understood or explained functionally.

Artificial Intelligence↗

PubMedDate not supplied

Intrinsic pedal musculature support of the medial longitudinal arch: an electromyography study.

Much of the work describing support of the medial longitudinal arch has focused on the plantar fascia and the extrinsic muscles. There is little research concerning the function of intrinsic muscles in the maintenance of the medial longitudinal arch. Ten healthy volunteer adults served as subjects for this study, which was approved by the University Investigational Review Board. The height of the navicular tubercle above the floor was measured in both feet while subjects were seated with the foot in a subtalar neutral position and then when standing in a relaxed calcaneal stance. Subtalar neutral was found by palpating for talar congruency. Recordings of muscle activity from the abductor hallucis muscle were performed while the subjects maintained a maximal voluntary contraction in a supine position by plantarflexing their great toes. An injection of lidocaine (1% with epinephrine) was then administered by a Board-certified orthopedic surgeon in the region of the tibial nerve, posterior and inferior to the medial malleolus. Measurements were repeated and compared by using a paired t test. After the nerve block, the muscle activity was 26.8% of the control condition (P =.011). This corresponded with an increase in navicular drop of 3.8 mm. (P =.022). The observation that navicular drop increased when the activity of the intrinsic muscles decreased indicates that the intrinsic pedal muscles play an important role in support of the medial longitudinal arch.

Adult↗