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Biomedical subjects

Mark S Granick

Publications and source records attributed to Mark S Granick.

9 recordsLinked to original sources
PubMed2005

Skin flaps.

Open wounds, particularly around the face, often require complicated techniques for optimal closure. The approach to the closure of the complicated wound depends largely on the nature of the wound, including the location and size of the defect, the functional outcome after closure, the medical comorbidities of the patient, neighboring structures, and whether the defect is secondary to a malignancy or trauma. The goals of wound management are optimal aesthetic outcome, preservation of function, and patient satisfaction. The authors briefly review basic skin closure options and discuss use of skin flaps, particularly of the head and neck region.

Facial Injuries↗
PubMed2004

Plastic surgery considerations for holoprosencephaly patients.

Holoprosencephaly (HPE) is considered the leading abnormality of the brain and face in humans and is frequently associated with a wide spectrum of specific craniofacial anomalies including mid-line facial clefts, cyclopia and nasal irregularities. A standard course of treatment has not been developed and management is symptomatic and supportive. In this work, the authors discuss the wide-ranging spectrum of HPE and propose surgical guidelines to provide more uniform and appropriate care to patients suffering from holoprosencephaly. Assessment of the patient's brain abnormality is essential in determining the extent and benefit of surgical intervention. The authors discuss a median straight-line repair of the lip and repair of the anterior palate in a one-year old female and review the risks and benefits of surgery. Consistent with the ethical approach of surgical beneficence, the authors recommend intervention at the earliest possible time.

Cleft Lip↗
PubMed2004

Neurosurgical reconstruction with acellular cadaveric dermal matrix.

Acellular cadaveric dermal matrix (ACDM) is processed from human cadaver skin (AlloDerm; Life Cell Corp., Branchburg, NJ). It does not require an immediate blood supply but can transmit essential interstitial fluids for nourishment of overlying tissues. A number of neurosurgical reconstructions have required the use of tissue that fills these specifications. The material has been used most recently for reconstruction of dura during craniotomies when primary closure is not possible or harvesting from an autologous site is not available. Because ACDM is harvested from nonneurologic cadaveric tissues and because the cellular and antigenic elements have been removed from the matrix, prion diseases are not a transmission risk. We present 6 examples of previously unreported uses of ACDM for successful repair of meningomyelocele, cauda equina, encephalocele, cerebrospinal fluid fistula, and neuroma. We propose the use of ACDM as a valuable tool in neurosurgical reconstruction.

Adult↗
PubMed2004

The versatile V-Y flap for facial reconstruction.

BACKGROUND: There are many acceptable treatments for facial skin cancer, but some form of surgical excision is by far the most widely accepted. After surgical excision, there will necessarily be a defect that has to be managed. The V-Y flap is a very useful modality for repair of such defects in all zones of the face. OBJECTIVE: This article reviews the indications for V-Y flaps and the surgical technique that should result in a successful reconstruction. Each zone of the face is independently discussed, along with the appropriate variations in technique for each area. METHODS: An evaluation of the literature as well as the extensive experience of the senior author in performing this procedure provides the basis for this review. CONCLUSION: V-Y flaps are extremely versatile and relatively easy to perform. All areas of the face can be successfully reconstructed after skin cancer removal with V-Y flaps if they are properly designed and executed.

Facial Neoplasms↗
PubMed2003

Successful treatment of recalcitrant dissecting cellulitis of the scalp with complete scalp excision and split-thickness skin graft.

BACKGROUND: Dissecting cellulitis of the scalp (DCS) is a therapeutically challenging, chronic, progressive, suppurative disease of the scalp that is of unknown etiology. In addition to causing considerable discomfort and cosmetic disfigurement, long-standing lesions may result in the development of squamous cell carcinoma. Several treatment modalities for DCS have been employed with variable results. OBJECTIVE: To report the successful treatment of an aggressive, refractory case of DCS with complete scalp excision and split-thickness skin graft. METHODS: A 25-year-old black male with DCS was treated with complete scalp excision and split-thickness graft from the anterior thighs. RESULTS: The patient has remained free of disease activity and is satisfied with the cosmetic result. CONCLUSION: Complete scalp excision with split-thickness skin graft may be curative in patients with DCS and should be considered in recalcitrant cases that fail to respond to medical therapy.

Adult↗
PubMedDate not supplied

Efficacy and cost-effectiveness of a high-powered parallel waterjet for wound debridement.

Current concepts of wound healing acknowledge the essential role of wound bed preparation in achieving a wound with good healing potential. Critical to wound bed preparation is the removal of necrosis, unhealthy tissue, foreign matter, and infection. One of the accepted methods of wound bed preparation is surgery. The high-power parallel waterjet is a new surgical device, which allows the operator to remove very precisely undesirable tissue and debris with maximal preservation of viable tissue. A retrospective study was performed to evaluate the efficacy, safety, and economic impact of using this technique of surgical debridement. Forty patients who had waterjet debridements were compared with 22 patients with matched wounds who had conventional surgical debridement. The waterjet group had significantly fewer procedures (p<0.002) than the conventional group. Based on these outcomes, the use of the new device in appropriate patients is expected to lead to cost savings of approximately 1,900 dollars per patient.

Adult↗