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Biomedical subjects

Mark V Johnston

Publications and source records attributed to Mark V Johnston.

At least 19 recordsLinked to original sources
PubMed2006

A natural setting behavior management program for persons with acquired brain injury: a randomized controlled trial.

OBJECTIVE: To investigate the efficacy of a behavior management program delivered in the natural community setting for persons with brain injury and their caregivers. DESIGN: Three-group randomized controlled trial. SETTING: Homes and other community settings. PARTICIPANTS: Thirty-seven persons with traumatic and other acquired brain injury and their caregivers. INTERVENTIONS: Natural Setting Behavior Management (NSBM) involving education and individualized behavior modification program versus education only versus control group. MAIN OUTCOME MEASURES: Changes in frequency of targeted problematic behaviors. Subscale in Questionnaire on Resources and Stress, Maslach Burnout Inventory, and the Neurobehavioral Functioning Inventory. RESULTS: While no significant effects were detected at termination of education only (P<.075) or of NSBM (P<.56), significant treatment effects were found at the main outcome point 3 months after termination of services (P<.002). Rates of disruptive or aggressive behaviors declined significantly in the NSBM group. Differences in caregiver-rated stress, burden, and aggression were not statistically significant. CONCLUSIONS: A program of caregiver education and individualized behavior management in natural settings can decrease the frequency of disruptive behavioral challenges. Larger studies are needed to clarify the duration and intensity of education and individualized treatment required to diminish behavioral challenges and to understand relationships with general stress and burden experienced by caregivers.

Adult↗
PubMed2006

The structure of functional and community outcomes following traumatic brain injury.

OBJECTIVES: To investigate the dimensionality of functional and community outcomes following serious TBI. To identify items that fit, misfit or are redundant, as well as to assess person misfit. METHODS: Rating-scale (Rasch) analysis was applied to 1-year follow-up data from 231 cases in the US National TBI Model Systems database. Items selected for analysis included all items indicative of global outcomes, disability, activity or participation. RESULTS: A powerful singular measurement dimension was identified. Item reliability was very high (0.98), as was person reliability (0.97). The dimension fit over 90% of cases; that is approximately 10% of cases displayed anomalous patterns of functioning that indicated that their functioning was not measurable in terms of the general dimension identified. There was tension within the dimension between ratings of dependency (FIM) and cognitive functioning in everyday life (NFI). Most-but not all-neuropsychological test scores misfit the outcome dimension. CONCLUSIONS: Actual dimensionality was distinct from the named scales employed. A unidimensional measure model fit the data much better than expected. This outcome dimension might be called 'general community functioning'. In the future, it should be possible to develop more valid and parsimonious measures of community outcomes following TBI.

Activities of Daily Living↗
PubMed2006

Applying evidence standards to rehabilitation research.

OBJECTIVE: To describe evidence grading methods employed in the systematic reviews in this special series of articles. To provide an overview of results of these reviews to critique the quality of rehabilitation research. To identify issues in the application of evidence grading methods to rehabilitation. DESIGN: Conceptual review of evidence-based practice and evidence grading methods. English-language research studies on rehabilitation of persons with spinal cord injury, traumatic brain injury, and burn for the 5-yr period of 1999-2004 were reviewed using methods of the American Academy of Neurology supplemented by Cochrane criteria and summarized. RESULTS: Rehabilitation has a shortage of high-level studies. The number of level 1 treatment studies was quite limited (five in spinal cord injury, 15 in traumatic brain injury, 12 in burn rehabilitation), as was the number of level 2 studies (26, 4, and 2, respectively). Despite the large number of correlational studies published, the number of high-level (1 or 2) diagnostic and prognostic studies was surprisingly limited (34, 11, and 5, respectively). The rate of production of high-level studies is rapidly increasing. Problems were encountered in applying standard evidence criteria to complex issues encountered in some studies, suggesting limitations and issues in evidence grading methodology. CONCLUSIONS: Rehabilitation needs more high-level studies. Some improvements in research methodology are relatively affordable (e.g., improved blinding), whereas others are expensive (e.g., large randomized controlled trials). Lower-level investigations reporting promising results need to be followed by more definitive, higher-level trials.

Brain Injuries↗
PubMed2005

Community activities and individuals' satisfaction with them: quality of life in the first year after traumatic brain injury.

OBJECTIVE: To investigate the relations between community activities and satisfaction with these activities, desires to change them, and global life satisfaction. DESIGN: Interview study with follow-up 1 month after rehabilitation discharge and 12 months postinjury. SETTING: Community. PARTICIPANTS: One hundred sixty-two individuals hospitalized with mostly moderate-to-severe traumatic brain injury. About 90% were reached (mostly by phone) 1 month after rehabilitation discharge; 84.6%, at 12 months postinjury. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Community Integration Questionnaire-2, augmented by individuals' ratings of satisfaction or dissatisfaction with and desire to change each activity; and the Satisfaction With Life Scale. RESULTS: Although significant correlations were found for some items, most correlations between activities and ratings of global quality of life (QOL) were low and nonsignificant. Individuals reported that they were satisfied with most of their community activities, but there were exceptions (eg, paid work). Correlations between activity-specific satisfaction and general life satisfaction were generally weak and nonsignificant. Dissatisfaction with an activity correlated strongly with desire to change the activity, but general life satisfaction did not correlate with desire to change activities. CONCLUSIONS: The lack of association between frequency of activities and subjective appraisals of them is a challenge to outcomes measurement and has implications for the targeting of rehabilitative interventions and evaluation of their worth. More research is needed to understand how individualizing functional objectives might maximize the effects of rehabilitation on the QOL of persons served.

Adolescent↗
PubMed2005

A trial of neuropsychologic rehabilitation in mild-spectrum traumatic brain injury.

OBJECTIVE: To test the effectiveness of a neuropsychologic rehabilitation program consisting of psychotherapy and cognitive remediation in the treatment of the affective and neuropsychologic sequelae of mild-spectrum traumatic brain injury (TBI). DESIGN: Single-blind randomized, wait-listed controlled trial, with repeated measures and multiple baselines. SETTING: Outpatient clinic in northern New Jersey. PARTICIPANTS: Twenty persons with persisting complaints after mild and moderate TBI (11 in treatment group, 9 controls). INTERVENTIONS: The experimental group received both 50 minutes of individual cognitive-behavioral psychotherapy and 50 minutes of individual cognitive remediation, 3 times a week for 11 weeks. The control group was wait-listed and received treatment after conclusion of follow-up. MAIN OUTCOME MEASURES: Symptom Check List-90R General Symptom Index, plus scales of depression, anxiety, coping, attention, and neuropsychologic functioning. RESULTS: Compared with the control group, the treatment group showed significantly improved emotional functioning, including lessened anxiety and depression. Most significant improvements in emotional distress were noted at 1 month and 3 months posttreatment. Performance on a measure of divided auditory attention also improved, but no changes were noted in community integration scores. CONCLUSIONS: Cognitive behavioral psychotherapy and cognitive remediation appear to diminish psychologic distress and improve cognitive functioning among community-living persons with mild and moderate TBI.

Adult↗
PubMed2005

Preventive services and health behaviors among people with spinal cord injury.

BACKGROUND/OBJECTIVE: To document receipt of certain understudied preventive services and health behaviors in spinal cord injury (SCI) and to compare them to the general adult population. METHODS: Cross-sectional survey. PARTICIPANTS: One hundred ninety-nine community-living adults with SCI residing in New Jersey. MAIN OUTCOME MEASURES: Receipt of recommended general preventive health services, such as screening for colorectal and prostate cancer and dental examinations, and health-related behaviors, including injury prevention, obesity, and tobacco use, as assessed by survey items in the Behavioral Risk Factors Surveillance System. RESULTS: Deficiencies in provision of needed preventive services were evident but were similar to those noted in the general adult population. Among participants 50 years of age or older, 47% had not had either a stool test for occult blood in the last year or a sigmoidoscopy/colonoscopy in the last 5 years. While 43.9% of participants were overweight or obese and 46.3% of these were trying to lose weight, only 1 3.8% had been counseled to lose weight. Twenty-two percent smoked on at least some days. Safety problems were evident: 15.5% did not use seatbelts consistently; 44% had not discussed a fire escape plan at home; and smoke detectors were often not checked adequately. Twelve and a half percent of participants reported having injuries during the last year, and fully 75% of these were related to SCI. Emergency room use and hospitalization were frequent. Participants had a median of 3 to 5 current doctors. CONCLUSIONS: Persons with SCI need the general screening and safety services recommended for all persons. Enhanced efforts will be needed to meet national goals in Healthy People 2010 in SCI.

Adult↗
PubMed2005

Health literacy, morbidity, and quality of life among individuals with spinal cord injury.

OBJECTIVES: Health literacy has been related to indicators of health outcomes in a number of populations, but not in spinal cord injury (SCI). The current study aimed to describe levels of health literacy in SCI and to investigate its possible associations with morbidity, health-related quality of life, functional independence, community participation, and life satisfaction. DESIGN: Cross-sectional survey of 107 community-living people with SCI recruited in a New Jersey outpatient SCI center. Primary measures were the Test of Functional Health Literacy in Adults (TOFHLA), standard questions about morbidity from the Behavioral Risk Factors Surveillance Study, the Craig Handicap Assessment and Reporting Technique (CHART), Short Form-12 (SF-12), and Diener's Satisfaction with Life Scale. RESULTS: Health literacy was marginal or inadequate (TOFHLA = 0-74) in only 14% of the sample. TOFHLA scores correlated significantly with physical health morbidity, even after control for severity of motor paralysis and education. American Spinal Injury Association (ASIA) Motor Scores were correlated with physical morbidity and CHART Physical Independence scores; and education was related to community Mobility, Occupation, and Economic Independence, and Satisfaction with Life scores, independent of other factors. Rasch analysis identified ceiling measurement limitations in the TOFHLA. CONCLUSIONS: Health literacy levels in this sample were higher than those found in other groups. Health literacy was independently related to physical health morbidity, but its associations with other outcomes were limited, entwined with education, and affected by severity of injury. Future research might examine higher-level aspects of health literacy to overcome ceiling measurement problems. Mediators of the association between health literacy and morbidity, such as health self-care behaviors, should also be examined.

Adult↗
PubMed2004

Relationships between level of disability and receipt of preventive health services.

OBJECTIVES: To examine relationships between level of disability and receipt of certain preventive health services, including demographic and systems variables that may explain or confound these relationships. DESIGN: Analysis of recent (1998 and 2000) data from the Behavioral Risk Factor Surveillance System, a nationwide telephone survey. SETTING: States reporting data on disability (13 in 1998, 18 in 2000). PARTICIPANTS: Noninstitutionalized persons living in the community. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Frequency of receipt of recommended preventive health services, including colorectal, cervical, and breast cancer screening, and influenza and pneumococcal vaccination. An ordinal index of disability severity was constructed from questions on activity limitations. RESULTS: In 2000, people with mild and moderate disability received influenza and pneumonia vaccinations somewhat more frequently than people without disabilities, but people with the most severe disabilities least frequently received vaccinations that year. Disabled women received fewer Papanicolaou tests and clinical breast examinations, but significant differences did not occur for mammograms in 2000. Fewer differences as a function of disability level were apparent in 2000 than 1998. Demographic variables affected receipt of most preventive services. Access to routine checkups affected all preventive services independent of disability level in both years. CONCLUSIONS: Severity of disability is related to receipt of certain preventive services but not necessarily in a simple or unidirectional way. Regardless of disability, receipt of a checkup was an important determinant of receipt of preventive health services. For almost all services and groups studied, preventive care remained below targeted goals for Healthy People 2010.

Persons with Disabilities↗
PubMed2004

Structured exercise improves calf muscle pump function in chronic venous insufficiency: a randomized trial.

OBJECTIVE: Deterioration of calf muscle pump function is associated with progression of chronic venous insufficiency (CVI). We postulated that a supervised exercise program would improve calf muscle strength and venous hemodynamics in patients with CVI. METHODS: We recruited 31 patients for this randomized, prospective trial. Inclusion criteria required the presence of skin changes or ulceration (CEAP 4, 5, 6), and duplex ultrasound scanning (reflux or scarring) and air plethysmographic (APG) evidence of CVI. Subjects were randomized into control (n = 13) and therapy (n = 18) groups. Class II (30-40 mm Hg) compression hosiery was given to all. The experimental group received physical therapy designed specifically to strengthen calf musculature. Dynamic strength and power were measured with a Biodex II dynamometer (Biodex Medical Systems, Shirley, NY) at slow and fast speeds. Reflux (venous filling index) and calf pump function (ejection fraction, residual volume fraction) were measured with APG. Quality-of-life questionnaires and venous severity scores were also administered. Outcomes were compared 6 months after initiation of exercise. Probability of treatment effect was tested with univariate analysis of variance, with control for baseline values. RESULTS: Demographic variables and medical comorbidities were not different between groups. After 6 months of intervention, indicators of calf pump function returned to a normal range in the therapy (experimental) group. Mean residual volume fraction was improved in the exercise group (-8.75 +/- 4.6 vs 3.4 +/- 2.9 in the control group; P <.029). Mean ejection fraction was increased in the exercise group (3.48 +/- 2.7 vs -1.4 +/- 2.1 in the control group; P <.026). Reflux, while substantially greater than the normal value of 2.0 mL/s in both groups, was unchanged. The exercise regimen improved isokinetic peak torque/body weight at both slow speed (3.1 +/- 1.4 in the therapy group vs -1.0 +/- 1.1 in the control group; P <.05) and fast speed (2.8 +/- 0.9 in the therapy group vs - 0.3 +/- 0.6 in the control group; P <.03). No changes were observed in quality-of-life or severity scores. CONCLUSIONS: Calf muscle pump function and dynamic calf muscle strength were improved after a 6-month program of structured exercise. Directed physical conditioning of the calf musculature may prove beneficial for patients with or without alternative management options for severe CVI. Further research on exercise for patients with CVI is warranted.

Aged↗
PubMed2004

Perceived quality of care and outcomes following spinal cord injury: minority status in the context of multiple predictors.

OBJECTIVE: To determine whether patients with spinal cord injury (SCI) who are members of minority groups experience a disadvantage with regard to quality of care, and investigate predictors of perceived quality of care and indicators of outcome. DESIGN: Correlational analysis of longitudinal data. SAMPLE: One hundred and forty-three individuals with SCI in the first year following injury (43.3% tetraplegia, 56.7% paraplegia; 53.6% of total had complete injuries). SETTING: Hospital and postdischarge (usually outpatient) care at 3 SCI model systems. MAIN OUTCOME MEASURES: Perceived quality of acute, rehabilitative, and continuing care rated by patients according to standard format. Objective indicators of amount of care (eg, length of stay [LOS], charges) and outcomes (eg, medical complications, Functional Independence Measure [FIM] scores, a life satisfaction measure [the Diener Scale], and the Craig Handicap and Reporting Technique [CHART; a community participation scale]). RESULTS: Minorities did not report statistically significant differences in perceived quality of care or other indicators (eg, amount of care, medical complications, FIM gain, life satisfaction, and CHART scores) compared with other groups. Severity of injury affected LOS and activity outcomes. Satisfaction with medical care before the injury significantly predicted perceived quality of acute hospital care, inpatient rehabilitation, and continuing care (P < 0.03, 0.02, and 0.02, respectively). CONCLUSION: A number of factors may affect variations in perceived quality of care and outcomes, but ethnicity is not always the most important predictor. Asking patients about their satisfaction with previous care can assist in distinguishing satisfaction with current care from pre-existing biases.

Adult↗
PubMed2004

The effects of physician empathy on patient satisfaction and compliance.

The present study attempted to develop new scales of patient-perceived, empathy-related constructs and to test a model of the relationships of physician empathy and related constructs to patient satisfaction and compliance. Five hundred fifty outpatients at a large university hospital in Korea were interviewed with the questionnaire. The data were analyzed using structural equation modeling. Patient-perceived physician empathy significantly influenced patient satisfaction and compliance via the mediating factors of information exchange, perceived expertise, inter-personal trust, and partnership. Improving physician empathic communication skills should increase patient satisfaction and compliance. Health providers who wish to improve patient satisfaction and compliance should first identify components of their empathic communication needing improvement and then try to refine their skills to better serve patients.

Communication↗
PubMed2003

Characteristics of effective and efficient rehabilitation programs.

OBJECTIVE: To investigate the characteristics of rehabilitation hospitals and units correlated with gains in motor and cognitive function, after adjusting for case severity of the patients admitted and for length of stay (LOS). DESIGN: The Uniform Data System for Medical Rehabilitation (UDSMR) database was first analyzed to develop a method of adjusting for patient case severity on admission. Rehabilitation programs were surveyed to assess characteristics commonly thought to be associated with efficiency and effectiveness. Data on these characteristics were linked to UDSMR data on patient characteristics and functional gain. SETTING: Seventy-seven rehabilitation hospitals across the United States. PARTICIPANTS: A total of 37,692 inpatients from the participating rehabilitation hospitals. INTERVENTION: Comprehensive rehabilitation programs not altered by researcher. MAIN OUTCOME MEASURES: Program effectiveness was estimated by gains in motor and cognitive subscale scores of the FIM trade mark instrument between admission and discharge, adjusted for indicators of caseload severity at admission. Efficiency was estimated by adjusting gains for LOS as well. RESULTS: Primary factors affecting both motor and cognitive gains included admission function (treated curvilinearly), age, certain diagnostic distinctions, onset-admission interval, admission class, and LOS. Correlations between staffing intensity and numerous other program characteristics with functional gain were meager, each accounting for less than 2% of variance. LOS was predicted by a number of factors, notably by the percentage of managed care cases (r=-.20), but not by staffing intensity. CONCLUSIONS: Relationships between rehabilitation practices and functional gains by patients do not appear to be simple or overt. Continued research is needed to identify reliable connections between rehabilitative processes and patient outcomes in practice.

Aged↗
PubMed2003

Telerehabilitation, cognition and user-accessibility.

Survivors of traumatic brain injury (TBI) often experience cognitive and physical impairments. The aims of this study were to: 1) build an internet-based, "Virtual Rehabilitation Center" (VRC) that provides rehabilitation, education and support services to individuals with TBI; and 2) to determine the relationships between the nature and severity of the participants' cognitive impairments and their ability to use the VRC. Eight individuals with brain injuries (Age: M=43, SD=15.4; Years of Education: M=13.8, SD=3.15) participated. The Neurobehavioral Cognitive Status Exam (NBCSE) was used to assess intellectual functioning. The VRC modules consisted of reaction time, functional modules, and communication capabilities. All participants learned how to use the VRC. However, those requiring more "trials to acquisition" showed greater cognitive impairment than those requiring fewer trials in: Construction (p=0.02), Reasoning-Similarities (p=0.01) and in calculation and language repetition.(i.e., a non-significant trend). Importantly, all participants learned how to use the system although learning rates varied. Moreover, one case-study demonstrated that learning on the VRC generalized to the community. Overall, impairments on the NBCSE in visual-constructional integration and executive-type functions, as well as language processing appeared to be related to how effectively participants learned how to use the VRC.

Adult↗
PubMed2002

Modified constraint-induced therapy in subacute stroke: a case report.

OBJECTIVE: To determine the efficacy of a modified constraint-induced therapy (CIT) protocol administered to a patient with subacute stroke. DESIGN: Multiple-baseline, before-after trial. SETTING: Subacute outpatient clinic. PATIENT: A 68-year-old woman who had a left anterior cerebral artery infarct 5 months before study entry and who exhibited learned nonuse of the affected upper limb. INTERVENTION: Thirty minutes of structured physical therapy and 30 minutes of occupational therapy 3 times a week for 10 weeks, each session emphasizing affected arm use. During the same period, her unaffected arm and hand were restrained 5d/wk during 5 hours initially identified as a time of frequent use. MAIN OUTCOME MEASURES: The Fugl-Meyer Assessment of Motor Recovery (FMA), Action Research Arm Test (ARA), Wolf Motor Function Test (WMFT), and Motor Activity Log (MAL). RESULTS: The patient exhibited substantial improvements on the FMA and ARA. She also improved on the WMFT in her ability to perform tasks and in the time taken to complete the tasks. Amount and quality of arm use also improved, as measured by the MAL. CONCLUSIONS: Modified CIT may be an efficacious method of improving function and use of the affected arms of patients with learned nonuse.

Activities of Daily Living↗
PubMed2002

Activity-related quality of life in rehabilitation and traumatic brain injury.

OBJECTIVES: To review approaches to assessment of quality of life (QOL) outcomes in rehabilitation, focusing particularly on traumatic brain injury (TBI), and to introduce the concept of activity-related QOL. DATA SOURCES: A conceptual review, based on extensive searches of MEDLINE, PsychInfo, and other information sources. STUDY SELECTION: Studies indexed under QOL and brain injury. DATA EXTRACTION: Literature search on key words quality of life and traumatic brain injury. DATA SYNTHESIS: Past research in rehabilitation and TBI has concentrated largely on assessment of function or activity. Although research on QOL after TBI remains limited, many studies have made inferences about QOL without actually assessing it. Persons with TBI experience serious long-enduring problems with QOL. Progress has been made in measurement of QOL and understanding of predictors of QOL after TBI. CONCLUSIONS: Future research in rehabilitation would do well to consider not only activity outcomes but also the affective quality of everyday life, and the connections between the two. Measures of activity-related QOL may provide a more sensitive, valid, and useful evaluation of rehabilitative therapies than other approaches. Further research is needed to improve measurement and interpretation of QOL assessments. By assessing both objective and subjective features of outcomes, outcomes assessment becomes more complete and potentially more useful.

Activities of Daily Living↗
PubMed2002

Modified constraint-induced therapy after subacute stroke: a preliminary study.

OBJECTIVE: To determine the efficacy of a modified constraint-induced therapy (mCIT) administered to patients with subacute stroke. DESIGN: Prospective, multiple-baseline, before-after, randomized clinical trial. SETTING: Subacute outpatient clinic. SUBJECTS: Fourteen patients with subacute stroke who exhibited learned nonuse and stable motor deficits in their affected upper limbs. INTERVENTION: Four patients participated in half-hour, structured physical and occupational therapy sessions that emphasized affected arm use in valued functional activities, 3 times per week for 10 weeks. Their less affected upper limbs were restrained 5 days per week during 5 hours identified as times of frequent use (mCIT). Five patients received regular therapy (TR) with similar therapeutic contact time to mCIT and 5 patients received no therapy (CON). MAIN OUTCOME MEASURES: The Fugl-Meyer Assessment of Motor Recovery (Fugl), Action Research Arm (ARA) test, and Motor Activity Log (MAL). RESULTS: After intervention, Fugl, ARA, and MAL scores remained virtually the same for TR and CON groups; scores improved by 11.4 and 11.5points, respectively, on the Fugl and ARA for the mCIT group. Amount and quality of arm use, as measured by the MAL, also improvedfor mCIT patients (2.49 and 0.47, respectively). CONCLUSIONS: mCIT may be an efficacious method of improving affected arm function and use in stroke patients exhibiting learned nonuse.

Aged↗
PubMed2002

Stroke patients' and therapists' opinions of constraint-induced movement therapy.

OBJECTIVE: To determine the opinions of patients with stroke and therapists about constraint-induced movement therapy (CIT). SUBJECTS AND INTERVENTION: Two hundred and eight patients with stroke in the northeastern USA responded to a self-report questionnaire administered through the mail and via telephone interviews. A similar questionnaire was administered to 85 physical and occupational therapists in the northeastern USA during their clinical staff meetings. The questionnaire described CIT to participants using excerpts from a recently published CIT study. Subjects then responded to various statements concerning their opinions of the protocol and supplied rationale for their opinions. RESULTS: Sixty-eight per cent of patients said they were not interested in participating in CIT, citing concerns with the practice schedule and the restrictive device schedule. Therapists cited concerns about patient adherence and safety, and speculated that facilities may not have the clinical resources to provide CIT. CONCLUSIONS: Patients with stroke and therapists in some environments may hold sceptical views about the utility of CIT. Although it has been shown to be effective in laboratory research, CIT may have low clinical practicality in some environments.

Adolescent↗