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Biomedical subjects

Mary Sullivan

Publications and source records attributed to Mary Sullivan.

9 recordsLinked to original sources

Discriminating between cognitive and supportive group therapies for chronic mental illness.

This descriptive and comparative study employed a Q-sort process to describe common factors of therapy in two group therapies for inpatients with chronic mental illness. While pharmacological treatments for chronic mental illness are prominent, there is growing evidence that cognitive therapy is also efficacious. Groups examined were part of a larger study comparing the added benefits of cognitive versus supportive group therapy to the treatment milieu. In general, items described the therapist's attitudes and behaviors, the participants' attitudes and behaviors, or the group interactions. Results present items that were most and least characteristic of each therapy and items that discriminate between the two modalities. Therapists in both groups demonstrated good therapy skills. However, the cognitive group was described as being more motivated and active than the supportive group, indicating that the groups differed in terms of common as well as specific factors of treatment.

Adult↗

Long-term married couples' health promotion behaviors: identifying factors that impact decision-making.

Knowledge about health promotion behaviors and their determinants in older individuals is scant. Even less is known about persons in long-term marriages, although a growing interdependence in health decision-making has been suggested. The purpose of this study was to identify determinants of health promotion activities in older adults who were in long-term marriages. Pender's Health Promotion Model and a proposed re-conceptualization of Pender's interpersonal influences were used to guide selection of study variables. Perceived barriers and perceived self-efficacy, two behavior-specific cognitions, and relationship quality and social support, proposed interpersonal influences, were hypothesized to predict participation in health promotion behaviors. A convenience sample of 80 individuals in long-term marriages was recruited. Regression analysis identified four predictor variables as explaining 31% of the participation in health promotion behaviors: relationship quality, perceived barriers, perceived self-efficacy, and social support. Implications for nursing practice and for further research are discussed.

Aged↗

Expectations for walking speeds: standards for students in elementary schools.

PURPOSE: The aim of this study was to determine children's walking speeds in elementary school hallways. A second aim was to determine the slowest but "good enough" walking speed if a teacher had to slow down her class's line to accommodate a student with a mobility limitation. METHODS: The walking speeds of 370 children serving as class-line leaders were determined after measuring using a stopwatch the time that it took to walk along 50-ft paths in school hallways. Teachers were asked to demonstrate a "good enough" speed for a child with mobility limitations after instruction and demonstration of slow walking by a physical therapist (PT). The teachers "good enough" speed was determined after measuring with a stopwatch the time that it took for the teacher to walk a distance of 50 ft imitating a "good enough" speed. RESULTS: Significant speed differences were found between children in kindergarten through sixth grade. The mean speed to walk 50 ft used by kindergarten line leaders was 13.5 seconds, and the speed increased to 50 ft in 10.6 seconds for sixth grade lines. Teacher "good enough" times were significantly different from the children's times at every grade level. CONCLUSIONS: These peer-based school standards can be used by PTs, parents, teachers, and other Individualized Education Program team members to make realistic decisions about future goals for preschool and elementary school children with mobility limitations so that they can participate with their peers.

Adolescent↗

Palivizumab prophylaxis of respiratory syncytial virus disease in 2000-2001: results from The Palivizumab Outcomes Registry.

The objective of the Registry was to characterize the population of infants receiving prophylaxis for respiratory syncytial virus (RSV) disease by describing the patterns and scope of usage of palivizumab in a cross section of US infants. RSV hospitalization outcomes were also described. The Palivizumab (Synagis, MedImmune, Inc., 25 West Watkins Mill Road, Gaithersburg, MD 20878) Outcomes Registry was a prospective multicenter survey conducted at 63 sites. Demographics, injection history, and RSV hospitalization outcomes were collected on 2,116 infants receiving palivizumab. Infants were enrolled in the Registry between September 1, 2000-March 1, 2001, at the time of their first injection. Infants born at less than 32 weeks of gestation accounted for 47% of infants enrolled, and those between 32-35 weeks accounted for 45%; approximately 8% were greater than 35 weeks of gestation. Lower RSV hospitalization rates were observed in infants who had greater adherence to regularly scheduled injections. Nearly one-half of all hospitalizations occurred within the first and second injection intervals, suggesting the importance of early RSV protection. The confirmed RSV hospitalization rate of all infants in the Registry was 2.9%; the rate was 5.8% in infants with chronic lung disease of infancy, and 2.1% in premature infants without chronic lung disease. In conclusion, these data support the continued effectiveness of palivizumab prophylaxis for severe RSV lower respiratory tract disease in a large cohort of high-risk infants from geographically diverse pediatric offices and clinics. The Palivizumab Outcomes Registry provides an opportunity to assess palivizumab utilization and clinical effectiveness in the US.

Antibodies, Monoclonal↗

Bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease: results of six patients.

In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were completed before and after surgery in a double-blind fashion under the following six conditions: (a) on medication, (b) off medication, (c) on medication/on stimulation, (d) on medication/off stimulation, (e) off medication/on stimulation, and (f) off medication/off stimulation. On average, improvement was noted in all areas including the Unified Parkinson's Disease Rating Scale, Schwab and England Activities of Daily Living Scale, Modified Hoehn and Yahr Staging, and timed tests: In addition, dyskinesia duration and dyskinesia disability were reduced.

Activities of Daily Living↗

Birth weight, neonatal morbidities, and school age outcomes in full-term and preterm infants.

In this prospective longitudinal study, birth weight and neonatal morbidities were evaluated relative to a broad range of school age outcomes. Fully 188 infants, 151 who were preterm, were recruited at birth, stratified by birth weight and socioeconomic status, and were followed until age 8 with a 97% retention rate. A gradient relationship was found among birth groups, with full-term children earning the highest scores. The very low birth weight and extremely low birth weight groups were equivocal in all scores except visual perception. The findings also were consistent with a pattern of nonverbal learning disability (Rourke, 1995) in which there is evidence of math underachievement and adequate performance in verbal, reading, and spelling scores. Children who had bronchopulmonary dysplasia, chronic lung disease, intraventricular hemorrhage, and sepsis differed from children without these neonatal morbidities, with an average of 10-20 points below the mean.

Birth Weight↗

Testing proximal and distal protective processes in preterm high-risk children.

The purpose was to examine a model that incorporates cumulative medical risk at age 4 and distal and protective processes at age 8 to assess school-age competency outcomes of cognition, school achievement, and socioemotional well-being in a sample of preterm children born at various degrees of medical risk. Cumulative medical risk and distal protective and proximal maternal protective processes were constructed into indexes. Hierarchical multiple regression analysis were performed entering the cumulative medical risk index first, followed by distal and proximal protective processes in the next two steps to test the effect on cognitive, academic, and socioemotional competence. For participants, 151 preterm and 39 full-term infants were recruited at birth into a prospective longitudinal study and followed until age 8 with a 97% retention rate. Children were stratified by birth weight and socioeconomic status. The hypotheses were supported. Significant main effects for cumulative medical risk and distal and proximal protective processes in all competency outcome models are key findings. The addition of protective processes was small to moderate in effect (6%-18%) yet clinically significant. These findings illustrate the advantage of applying cumulative medical risk and protection approach to better understand school-age outcomes. Multiple risk and protective models emphasize the joint occurrence of individual contextual processes in the understanding of competence outcomes in high-risk children.

Apgar Score↗

Early precursors of low attention and hyperactivity in a preterm sample at age four.

The increased numbers of low birth weight (LBW) survivors has raised questions about the direct association between LBW and later diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in early childhood. A longitudinal data set was used to determine the relationship among perinatal morbidity and medical and neurological status during the toddler period (18 and 30 months) with lower attention and higher activity, cardinal features of ADHD at age 4. The sample of 39 full term and 149 preterm infants were recruited at birth. Infants were assigned to 1 of 5 groups based on perinatal morbidity. Medical and neurological status were classified as normal, suspect, or abnormal at 18 and 30 months. At age 4, five measures of attention and activity were gathered from parents and independent examiners. Multivariate analysis of variance (MANOVA) showed significant effects of perinatal morbidity, birth weight, gestational age, gender, socioeconomic status at infancy, and toddler medical and neurological status with lower attention and higher activity at age 4. Prematurity, perinatal illness, and later medical status are early markers for preschool behaviors associated with clinical diagnosis of ADHD.

Attention Deficit Disorder with Hyperactivity↗