PubMed Health⌕ Search

Biomedical subjects

Masaki Hanibuchi

Publications and source records attributed to Masaki Hanibuchi.

4 recordsLinked to original sources

[A case of septic pulmonary embolism accompanied with tricuspid valve endocarditis and pyogenic spondylitis].

A 54-year-old man was admitted with complaints of high fever and lumbago. A chest radiograph on admission showed bilateral multiple patchy infiltrations. Chest CT showed multiple nodules of various sizes, some with necrotic centers and feeding vessels in the peripheral areas. Some nodules had wedge-shaped consolidations aboutting the pleura. Echocardiography showed vegetation about 12 x 7 mm in size attached to the tricuspid valve. MR imaging of the lumbar vertebrae showed increased signal intensity in the vertebral bodies in L1-4 in T2-weighted images and a further increase of signal intensity by gadolinium enhancement in T1-weighted images. These findings led to a diagnosis of septic pulmonary embolism accompanied with tricuspid valve endocarditis and pyogenic spondylitis irrespective of a negative blood culture. The fever was reduced and the inflammatory findings and chest radiographs were improved by antibiotic therapy, and then tricuspid valvuloplasty was performed. The characteristic CT features of septic pulmonary embolism, mentioned above, can contribute to an accurate and early diagnosis and proper treatment.

Endocarditis, Bacterial↗

Anaplastic large-cell lymphoma (Ki-1 lymphoma): ultrastructural and immunohistochemical studies.

We report an autopsy case of a malignant neutrophil-rich anaplastic large cell lymphoma (ALCL), which was reactive to the monoclonal antibody Ki-1 (CD30). This subtype of Ki-1 ALCL containing many neutrophils was named by Mann and colleagues in 1995, and its clinical and pathological characteristics have not been well described. In our case, the patient died 2 months after he first noticed an abdominal skin tumor. It was difficult to make the exact diagnosis of malignant lymphoma because the histological examination showed very poorly differentiated tumor cells. Ultrastructural observations revealed nuclei with convoluted contours and, sometimes, deep indentations, which suggested ALCL. Immunohistologically, most neoplastic cells were reactive with Ki-1 (CD30), leukocyte common antigen (LCA), and CD45RO (UCHL-1), and we confirmed Ki-1 ALCL. When we encounter poorly differentiated tumors on light microscopy, we should perform immunohistochemistry for hematological markers, such as LCA and Ki-1.

Adult↗

[Two cases of pulmonary eosinophilic granuloma with multiple nodular shadows].

We encountered two rare cases of pulmonary eosinophilic granuloma with multiple nodular shadows in both lungs. The patient in case 1 was a 54-year-old man complaining of dry cough and chest pain. He had smoked 20 cigarettes a day for 36 years. The patient in case 2 was a 37-year-old woman complaining of dry cough. She had smoked 15 cigarettes a day for 20 years. Chest radiography and CT revealed multiple nodular shadows in both lungs. Diagnosis was made by open lung biopsy in case 1 and by percutaneous lung biopsy in case 2. After smoking cessation, symptoms improved markedly and the shadows in the chest radiographs and CT disappeared. In cases of bilateral multiple nodular shadows, other than metastatic lung tumor cases, pulmonary eosinophilic granuloma should be considered.

Adult↗