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Masako Kubo

Publications and source records attributed to Masako Kubo.

2 recordsLinked to original sources

Suicidal ideation and alexithymia in patients with alcoholism: a pilot study.

OBJECTIVE: Suicidal incidences are known to be high in patients manifesting alcoholism. We attempted to characterize suicidal ideation in Japanese patients with alcoholism in relation to alexithymia. METHODS: Eighty-five male alcoholic patients, hospitalized in the alcoholics ward of a mental hospital and aged between 40 to 69 (52.9 +/- 8.3 years), and 79 nonalcoholic males in the same age range (54.9 +/- 7.1 years) recruited from a municipal garbage disposal plant were included in the study. The patients were evaluated using the Scale of Suicidal Ideation (SSI) and the Toronto Alexithymia Scale (TAS) during 2002. RESULTS: Of the alcoholic patients, 76.6% belonged to the high-risk group of suicidal ideation (SSI > 2), and 66.6% of the high-risk patients were alexithymic. In contrast, 86.1% of the nonalcoholic controls showed no suicidal ideation and only 17.7% of those without suicidal ideation were alexithymic. When the alcoholic patients with intensive suicidal ideation were compared with nonalcoholic patients without suicidal ideation, the scores of factor 1 and factor 2 were significantly higher in the former group (p < 0.001). CONCLUSIONS: Alcoholic patients with intensive suicidal ideation accompanied with alexithymia are characterized by the inability to communicate feelings. Therefore, the possibility of a suicidal attempt in those patients should always be kept in mind even though no suicide message is expressed.

Adult↗

Executive cognitive dysfunction without stroke after long-term mechanical circulatory support.

Among patients who receive heart transplantation (HTx) after long-term mechanical circulatory support (MCS), some show executive cognitive dysfunction without a history of stroke. Fifty HTx patients (19 patients on MCS for longer than 3 months before HTx and 31 patients without MCS as control group) were enrolled in the study. All subjects were men aged between 20 and 59 years without a history of stroke. Patients with MCS were divided into two groups: the AH-Thr group (n = 11), in which thrombus was detected in the left ventricular assist device (LVAD) and quickly removed (mean 3.3 times); and the AH group (n = 8), in which there was no detectable thrombus in the LVAD. The Trail Making Test (TMT) and the Wisconsin Card Sorting Test (WCST) were administered. The AH-Thr group showed poorer cognitive performance both in the TMT part B, with longer completion time (p < 0.05 versus the other two groups), and in the WCST, with more perseverative errors (p < 0.001 versus the other two groups). These data indicate that patients in the AH-Thr group showed executive cognitive dysfunction in set-shifting ability, suggesting frontal lobe damage. The conditions that facilitate thrombus formation in the LVAD may induce executive cognitive dysfunction without stroke.

Adult↗