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Biomedical subjects

Matti Uhari

Publications and source records attributed to Matti Uhari.

8 recordsLinked to original sources
PubMed2003

Dietary factors protecting women from urinary tract infection.

BACKGROUND: Because urinary tract infections (UTIs) are caused by bacteria in the stool, dietary factors may affect the risk of contracting a UTI by altering the properties of the fecal bacterial flora. OBJECTIVE: We studied dietary and other risk factors for UTI in fertile women in a case-control setting. DESIGN: One hundred thirty-nine women from a health center for university students or from the staff of a university hospital (mean age: 30.5 y) with a diagnosis of an acute UTI were compared with 185 age-matched women with no episodes of UTIs during the past 5 y. Data on the women's dietary and other lifestyle habits were collected by questionnaire. A risk profile for UTI expressed in the form of adjusted odds ratios (ORs) with 95% CIs was modeled in logistic regression analysis for 107 case-control pairs with all relevant information. RESULTS: Frequent consumption of fresh juices, especially berry juices, and fermented milk products containing probiotic bacteria was associated with a decreased risk of recurrence of UTI: the OR for UTI was 0.66 (95% CI: 0.48, 0.92) per 2 dL juice. A preference for berry juice over other juices gave an OR of 0.28 (95% CI: 0.14, 0.56). Consumption of fermented milk products > or = 3 times/wk gave an OR of 0.21 (95% CI: 0.06, 0.66) relative to consumption < 1 time/wk. Intercourse frequency was associated with an increased risk of UTI (OR for > or = 3 times/wk compared with < 1 time/wk: 2.7; 95% CI: 1.16, 6.2). CONCLUSION: Dietary habits seem to be an important risk factor for UTI recurrence in fertile women, and dietary guidance could be a first step toward prevention.

Adult↗
PubMed2003

Interobserver and intra-observer agreement in interpreting urodynamic measurements in children.

PURPOSE: We evaluated the comparability and repeatability of analyses based on urodynamic reports. MATERIALS AND METHODS: We assessed interobserver and intra-observer agreement when interpreting urodynamic examinations performed in children. Four pediatric urologists analyzed 17 sets of urodynamic data and gave their interpretations of the possible underlying condition of the tested subjects. The consensus among observers was analyzed using the kappa statistic. RESULTS: Poor agreement was observed on suggested diagnoses based on uroflow curves. Good consensus was noted on maximal flow rates but the interpretations of urethral pressure profile curves and the resulting diagnoses regarding sphincter function differed significantly. It also appeared to be difficult to reach agreement regarding bladder compliance and detrusor activity. CONCLUSIONS: The consistency of the interpretations of urodynamic studies should be improved before they are accepted as measures for comparing urodynamic diagnoses or effects of treatment between patient series.

Adolescent↗
PubMed2003

Paranasal sinus findings in children during respiratory infection evaluated with magnetic resonance imaging.

OBJECTIVE: The spreading of acute respiratory infection into the paranasal sinuses in children is poorly defined. The main objective of this study was to evaluate the frequency and spontaneous resolution of paranasal sinus abnormalities in children with acute respiratory infection using magnetic resonance imaging (MRI). METHODS: We examined 60 children with MRI (mean age: 5.7 years) with symptoms of acute respiratory infection. Twenty-six children with major abnormalities in the first MRI scan had a follow-up MRI taken 2 weeks later. RESULTS: The children had had symptoms of uncomplicated acute respiratory infection for an average of 6 days before the first examination (mean duration: 6.5; standard deviation: 3.0). Approximately 60% of the children had major abnormalities in their maxillary and ethmoidal sinuses, 35% in the sphenoidal sinuses, and 18% in the frontal sinuses. The most common abnormal finding was mucosal swelling. The mean overall MRI scores correlated significantly with the symptom scores (r(s) = 0.3). Of the individual symptoms, nasal obstruction, nasal discharge, and fever were significantly related to the MRI scores. Among the 26 children with major abnormalities in the first MRI, the findings subsequently improved significantly (mean [standard deviation] score: 12.7 [5.6] to 5.7 [5.2]), irrespective of the resolution of symptoms. CONCLUSIONS: These observations indicate that acute respiratory infection mostly spreads into the paranasal sinuses of children in the form of mucosal edema and that these abnormalities tend to resolve spontaneously without antimicrobial treatment.

Anti-Bacterial Agents↗
PubMed2002

Peer consultation as a method for promoting problem-based learning during a paediatrics course.

In problem-based learning (PBL) there are problems during tutorial group sessions, for example lack of participation, interaction and cohesion, and withdrawing. The authors evaluated whether these problems could be avoided with a peer consultation model. Peer consultation takes advantage of cooperation between students by encouraging them to accept more responsibility for learning from their peers. Forty-nine fifth-year students participated in three group sessions where they solved a paediatric case problem. The students were working in small groups, assuming the following roles in turn: presenters, facilitators and observers. The students reported that this consultative method forced one to actually define the problem, helped to develop communication skills and to identify problematic issues from different viewpoints and offered the possibility to evaluate personal problem-solving strategies. The method also gave an opportunity for students to learn in practice how to utilize new technology in data searching. These experiences suggest that the model of peer consultation adds new flavour, increasing enthusiasm in problem-based learning.

Cooperative Behavior↗
PubMed2002

Xylitol administered only during respiratory infections failed to prevent acute otitis media.

OBJECTIVE: As regular administration of xylitol had been effective in preventing acute otitis media (AOM) in children, we tested whether xylitol administered only at times of acute respiratory infection (ARI) reduces the occurrence of AOM. METHODS: Healthy children (N = 1277) were recruited from child care centers and randomized after screening with tympanometry to receive either control mixture (n = 212), xylitol mixture (n = 212), control chewing gum (n = 280), xylitol chewing gum (n = 286), or xylitol lozenges (n = 287) during an ARI. The trial was randomized and double blinded within the mixture and chewing gum groups. The parents began administering the products to their children at the onset of symptoms of ARI. The follow-up lasted until resolution of the symptoms or up to 3 weeks. RESULTS: A total of 1253 of the 1277 randomized children were eligible for the analysis. Altogether, 980 (78%) of 1253 children had at least 1 episode of ARI during the 4 months that the trial lasted. The occurrence of AOM during this episode was 34 (20.5%) of 166 in the xylitol mixture group, as compared with 32 (20.4%) of 157 among the children who received the control mixture. Among the older children who received control chewing gum, xylitol chewing gum, or xylitol lozenges, AOM was experienced by 24 (11.0%) of 218, 31 (14.1%) of 220, and 34 (15.5%) of 219, respectively. None of the differences between the groups was statistically significant. CONCLUSIONS: Xylitol administered only during an ARI was ineffective in preventing AOM.

Acute Disease↗