Biomedical subjects

Maurice Okello

Publications and source records attributed to Maurice Okello.

3 recordsLinked to original sources

PubMed2005

Homogeneous supported synthesis using ionic liquid supports: tunable separation properties.

[structure: see text] We report a homogeneous supported version of Koser's salt based on a room-temperature ionic liquid (RTIL) support. By altering the nature of the RTIL, a material was developed that was stable, recyclable, and readily separable from the tosyloxylated ketone products just by using variations in solvent polarity. A similar approach should be applicable to a wide range of supported catalysts and reagents.

Journal Article↗

PubMed2005

The 2-position of imidazolium ionic liquids: substitution and exchange.

The 2-position of imidazolium cations is known to be relatively acidic, leading to the useful Arduengo-type carbenes. At the same time, the acidity of this site can lead to undesired side reactions when using imidazolium-based ionic liquids as solvents. In this note, we describe the surprisingly facile deuterium exchange at this position and also the synthesis and exchange under modestly basic conditions (triethylamine) of a series of 2-methyl-substituted compounds.

Cations↗

PubMed2003

Solvents from biorenewable sources: ionic liquids based on fructose.

[reaction: see text] Fructose has been used as the starting material for the preparation of a new class of room-temperature ionic liquids (RTILs). These liquids exhibit tunable solvent properties much like conventional imidazole-based RTILs. They have been applied as recyclable solvents for the Heck reaction of aryl iodides.

Fructose↗