Biomedical subjects

Mehrnaz Asadi

Publications and source records attributed to Mehrnaz Asadi.

2 recordsLinked to original sources

PubMed2006

Therapeutic approach to "downhill" esophageal varices bleeding due to superior vena cava syndrome in Behcet's disease: a case report.

BACKGROUND: One of the rare presentations of superior vena cava syndrome is bleeding of "downhill" esophageal varices (DEV) and different approaches have been used to control it. This is a case report whose DEV was eradicated by band ligation for the first time. CASE PRESENTATION: We report a 42-year-old man who is a known case of Behcet's disease. The patient's first presentation was superior vena cava syndrome due to thrombosis followed by bipolar ulcers and arthralgia. He received warfarin, prednisolone and azathioprine. The clinical course of the patient was complicated by one episode of hematemesis without abdominal pain when the patient's PT was in therapeutic range. After resuscitation and correction of PT with fresh frozen plasma transfusion, upper gastrointestinal endoscopy was done. Prominent varices were seen in the upper third of the esophagus, tapering to the middle part without acute bleeding. Stomach and duodenum were normal. Color ultrasonography evaluation of the portal, hepatic and splenic veins was negative for thrombosis. Band ligation was done and the patient's bleeding did not recur. CONCLUSION: Band ligation is a safe and effective method for controlling DEV bleeding in patients with uncorrectable underlying disorders.

Adult↗

PubMed2006

Normative reference values for lung transfer factor in Isfahan, Iran.

OBJECTIVES AND BACKGROUND: Transfer factor or carbon monoxide diffusing capacity (DL(CO)) is a particularly valuable test of the appropriateness of gas exchange across the alveolocapillary membrane. The purpose of this study is to derive predictive equations for DL(CO) and its derivative volume-corrected DL(CO) (DL(CO)/VA) measured by single-breath method in a large non-smoking population sample in Isfahan. METHODOLOGY: We evaluated 1429 randomly selected subjects (732 men, aged 5-85 years). Gender-specific linear prediction equations were developed by multiple regression analysis; with measured DL(CO), and DL(CO)/VA values (mmol/min/kPa), as dependent variables regressed against age (A), height (H) and body surface area (BSA). RESULTS: For both genders, age had negative effects on DL(CO), while height had a positive effect on DL(CO) and DL(CO)/VA (P < 0.01). The prediction equations for DL(CO) and DL(CO)/VA are: '0.152 x height - 0.056 x age - 11.595' and '-0.12 x age + 2.467', for men and: '-0.035 x age - 0.133 x height - 10.707' and '-0.012 x age - 0.02 x height + 2.755', for women, respectively. CONCLUSIONS: Our results therefore provide an original frame of reference for either DL(CO) or DL(CO)/VA in Iranian population, obtained from a standardized single-breath technique.

Adolescent↗