Biomedical subjects

Meike Bock

Publications and source records attributed to Meike Bock.

3 recordsLinked to original sources

PubMed2004

Effects of CO2-enriched water on barrier recovery.

The objective of the present study was to evaluate the impact of CO2-enriched water on barrier recovery of detergent-damaged skin compared to tap water employing bioengineering methods and thin-layer chromatography (TLC) analysis of stratum corneum (SC) lipids. Irritation of the skin was elicited on the forearms of 20 volunteers using 1% sodium lauryl sulphate (SLS). The degree of skin irritation was followed over 10 days in terms of skin colour reflectance (L*a*b*), transepidermal water loss (TEWL), and skin capacitance expressed as median values. For TLC analysis, SC lipids were extracted prior to and during the observation period. Clinical examination showed the efficacy of CO2-enriched water on barrier recovery. Compared to unenriched tap water, CO2-enriched water produced a significant (P < 0.01) increase in total SC lipids and in particular in the ceramide fraction. Furthermore, TEWL was significantly (P < 0.01) lower in skin treated with CO2-enriched water than in skin treated with unenriched water. These findings may indicate that rinsing with CO2-enriched water enhances (1) clinical regeneration of detergent-damaged skin, (2) epidermal lipid synthesis, and (3) barrier repair after detergent-induced perturbation.

Adult↗

PubMed2004

Optimizing skin protection with semipermeable gloves.

BACKGROUND: Occlusion due to gloves is one important cause of glove irritation. Macerated softened skin gives poor protection against microbes and chemical injuries. The introduction of a breathable protective glove material would represent a significant step toward improved prevention of occupational skin disease. OBJECTIVE: Performance levels of semipermeable and occlusive gloves were examined under conditions typical of the hairdressing profession. In two studies, tests comparing breathable semipermeable gloves to single-use gloves made of occlusive materials were conducted. METHODS: In an initial study, a user survey was carried out in conjunction with bioengineering examinations. Values at baseline and values after gloves were worn were recorded by measuring transepidermal water loss (TEWL), skin humidity (SH), and skin surface hydrogen ion concentration (pH) in 20 healthy volunteers. In a second study, the gloves were tested for penetrability and permeability with three chemical compounds typically used in the hairdressing profession. RESULTS: Bioengineering examination objectively confirmed users' reports of reduced hand perspiration when semipermeable gloves were worn. The TEWL, SH, and skin surface pH values remained largely stable after 20 minutes of wearing semipermeable gloves, in contrast to the reactions observed with gloves of occlusive materials. Permeability tests indicated that the semipermeable material is effective, with some restrictions. Air leakage testing revealed that all 50 gloves tested were not airtight. CONCLUSION: Following the optimization of manufacturing methods, additional tests of the penetrability of semipermeable gloves will be necessary.

Adult↗

PubMed2003

Skin care management: educational aspects.

Health education is effective in primary, secondary and tertiary prevention of occupational skin disorders, as clearly demonstrated by interventional studies carried out at the University of Osnabrueck. Health education may intervene with (a) habituated behaviour of affected employees and (b) the condition of working environments. In conclusion, prevention of occupational skin diseases and maintenance of health can be achieved by the conditioning of individual behaviour via specific educational programmes in addition to dermatological care.

Beauty Culture↗