Biomedical subjects

Melanie L McCarty

Publications and source records attributed to Melanie L McCarty.

3 recordsLinked to original sources

PubMed2005

Minimal incision facelift surgery.

In today's active society and demanding workplace, patients are frequently searching for less invasive procedures with diminished morbidity and more rapid healing to address their cosmetic concerns. The goal of face-lift surgery is to reverse the effects of aging by removing excess skin of the lower face and neck with concomitant repositioning of the deeper ptotic tissues. Recent advances in understanding facial anatomy and aging have resulted in the development of new procedures that can achieve these goals with more limited surgery. As increasingly younger patients present for early restorative procedures, it is imperative that surgeons have alternative options within their armamentarium to achieve success. This article reviews the current trends in face-lift surgery, particularly the small incision face-lift.

Humans↗

PubMed2004

Manifestations of fungal cellulitis of the orbit in children with neutropenia and fever.

PURPOSE: To delineate clinical manifestations of fungal orbital cellulitis in immunocompromized patients. METHODS: The charts of 7 pediatric patients with fungal orbital cellulitis treated at a tertiary children's cancer hospital were reviewed retrospectively for histologically confirmed fungal sinusitis with associated orbital cellulitis. Patients underwent CT and/or MRI of the orbits, sinuses, and brain; surgery; and therapy with antifungal medications. Main outcome measures were presenting signs and patient survival. RESULTS: Twenty-four patients with fungal sinusitis were identified, 7 of whom (4 months to 15 years of age) had documented orbital fungal cellulitis. All 7 patients presented with neutropenia and fever. Presenting symptoms included edema of the upper eyelid (n=4), headache (n=1), and facial pain (n=1). One patient was asymptomatic. Although antifungal therapy was initiated within 24 hours of presentation, disease progressed, and 5 patients eventually died of their infections. CONCLUSIONS: Because fungal orbital cellulitis can be fatal even if detected early in patients who are immunocompromised, ophthalmologists and otolaryngologists should be alert to the disease's subtle clinical manifestations.

Adolescent↗

PubMed2003

Primary perineal alveolar rhabdomyosarcoma metastatic to an extraocular muscle.

A 17-year-old boy diagnosed with an alveolar rhabdomyosarcoma involving the perineum and with extensive lymphadenopathy was treated with chemotherapy yet developed metastases to the head and neck 6 months into therapy. Ten months after initial diagnosis, while receiving salvage chemotherapy and radiotherapy, he returned with pain on movement of his left eye, proptosis, and ptosis of the left upper eyelid. Computed tomography (CT) revealed a mass within the left lateral rectus muscle that biopsy confirmed to be metastatic alveolar rhabdomyosarcoma. Despite continued chemotherapy and radiotherapy, he ultimately died of the disease. Alveolar rhabdomyosarcoma from distant sites rarely metastasizes to the extraocular muscles. However, our case shows that alveolar rhabdomyosarcoma may metastasize to the orbit and involve a single muscle.

Adolescent↗