PubMed Health⌕ Search

Biomedical subjects

Melissa Endicott

Publications and source records attributed to Melissa Endicott.

2 recordsLinked to original sources

Principles of treatment for osteosarcoma.

Canine osteosarcoma accounts for 5% to 6% of all canine malignancies. A thorough workup is recommended to help clients make an educated decision about treatment options. Patients should be screened for concurrent diseases and early metastasis, as part of the diagnostic workup. Diagnostic techniques have improved to allow for more biopsy options. Once osteosarcoma is confirmed, there are many treatment options, both definitive and palliative, which can be offered to an owner. Amputation is no longer the only option that we can offer as treatment. Limb-sparing surgeries have become more common, and techniques in chemotherapy have significantly improved the median survival time in patients. Even if surgery is not an option, there are alternatives available to provide pain control and good quality of life. It is important to be versed in all the options to provide clients with the best possible recommendations.

Amputation, Surgical↗

Oncologic emergencies.

Cancer can lead to emergencies either due to the primary disease, or as a result of therapy. Appropriate diagnosis and rapid treatment of these conditions can result in survival of the patient. Whether chemotherapy is implemented or not, the clinician may be presented with a patient in need of emergency stabilization. Common occurring emergencies are related to effects of the cancer, ranging from immune dysfunction due to marrow infiltration to brain herniation due to increased intracranial pressure from neoplasia. Often adverse effects secondary to chemotherapy can cause emergency situations such as sepsis. Prompt diagnosis and treatment may result in a favorable outcome. Addressed in this chapter are commonly occurring emergencies and specific stabilizing treatments.

Animals↗