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Biomedical subjects

Metin Capar

Publications and source records attributed to Metin Capar.

4 recordsLinked to original sources
PubMed2004

Serum TNF-alpha, IL-6, lupus anticoagulant and anticardiolipin antibody in women with and without a past history of recurrent miscarriage.

OBJECTIVE: The aim of the this study was to investigate Lupus Anticoagulan (LA), Anticardiolipin Antibody (ACA), Tumor Necrosis Factor-alpha (TNF-alpha) and Interleukin-6 (IL-6) serum levels in 40 pregnant and 20 nonpregnant. MATERIALS AND METHODS: The women were divided into three groups. The first group consisted of 20 pregnant women of less than 20 gestational weeks and a past history of habitual abortion . The second group consisted of 20 non pregnant patients with a past history of habitual abortion. The third group consisted of 20 healthy non pregnant women. RESULT: LA was found in only one patient in the Group 2. ACA Ig G positivity were found 1 patient in the Group 1, 3 patients Group 2 and 1 patient in Group 3. Mean ACA IgG was highest in the Group 2. High serum TNF-alpha levels were found in the 12 (60%), 6(30%) and 2 (10%) women in the Groups 1, 2, and 3, respectively. Significant difference were found for TNF-alpha among the groups (P<0.05). The highest level of TNF-alpha was found in the Group 1 and the lowest in the Group 3. There were statistically significant differences for IL-6 among the three groups (P>0.05). CONCLUSION: We propose that cytokines especially TNF-alpha was found to be related to the pregnancy loss.

Abortion, Habitual↗
PubMed2004

Experience with vaginoplasty.

We did 27 vaginoplasties (7 gracilis musculocutaneous flaps, 8 pudendal thigh flaps, 12 full-thickness skin grafts) during the period 1994-2000. The preoperative assessment and postoperative follow up were done in collaboration with the gynaecologists. All patients had vaginal agenesis. With the gracilis flaps we found it difficult to achieve an adequate blood supply. With pudendal thigh flaps we achieved perfect innervation and a good contour, but they did tend to be hairy. With full-thickness skin grafts the innervation was not perfect, but the contour was good. Having compared the three operations during a follow up period ranging from 1-5 years we think that the full-thickness skin graft gives the best results.

Adolescent↗
PubMed2004

A new retropubic suspension operation technique for transvaginal Burch operation, using newly developed equipment.

BACKGROUND: Genuine stress urinary incontinence is a very common pathologic condition among women. In order to operate this, different techniques have been introduced. Here, a new technique is described for the operation of genuine stress urinary incontinence with newly developed equipment. The present technique offers more advantages than previous techniques introduced by different authors. With this technique, the duration of operation and of the recovery period are both shorter than with previous techniques. All patients had symptoms and signs of stress urinary loss. We performed multichannel cystometry preoperatively to all patients. METHOD: A special valve is used with reflector having 97% reflection capacity for transvaginal burch operation technique. Twenty five women (n = 25) having genuine stress urinary incontinence were taken under transvaginal Burch bladder neck suspension operation with fixation of suspension sutures to the Cooper (iliopectineal) ligament. RESULTS: Following urodynamic workup 6 months after the surgery, one out of the 25 patients (4%) was diagnosed to have genuine stress incontinence, while one patient (4%) were diagnosed as having urinary stress incontinence and detrussor instability. One patient was found to be wet postoperatively due to only detrussor instability (4%). There were no significant differences pre- and postoperatively regarding capacity, residual volume, pressure rise on filling or standing, or maximal voiding pressure or peak flow rate.

Adult↗