Michael D VanAuker | PubMed Health

PubMedDate not supplied

Effects of aging on the diagnostic assessment of valvular heart disease.

The diagnostic assessment of the severity of valvular heart disease in the older population is impacted by the anatomic and physiologic changes that accompany normal aging and by the interposition of diseases prevalent in the elderly. In this paper, the impact of those changes on the assessment of valvular heart disease will be reviewed. Special attention will be paid to the effects of age and disease on the measurement of the pressure drop and orifice area.

Aged↗

PubMedDate not supplied

Age-related changes in hemodynamics affecting valve performance.

Degenerative processes result in changes in both the aortic and mitral valves. For example, degenerative changes may lead to significant aortic stenosis or myxomatous mitral valves. Flows through each valve are determined not only by the properties of the valve itself, but also by the properties of proximal and distal chambers, which also undergo changes with age and diseases associated with the elderly, such as hypertension and coronary artery disease. Assessment of valvular performance should consider the effects of atrial-ventricular coupling (for the mitral valve) or ventricular-arterial coupling (for the aortic valve). Design of therapy or intervention should accordingly consider effects on the system as a whole.

Aged↗