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Michael E Spieth

Publications and source records attributed to Michael E Spieth.

27 records · Page 2Linked to original sources
PubMed2002

Thyroid carcinoma: iodine-131-negative whole-body scan reverses to positive after a combination of thyrogen stimulation and withdrawal.

PURPOSE: Reports state that scan results for as many as 25% of patients with differentiated thyroid carcinoma will convert to iodine-131 (I-131) negative over time with positive thyroglobulin levels. Tl-201, positron emission tomography (PET), and sestamibi or tetrofosmin have all helped to identify I-131-negative thyroid carcinomas. The authors have identified a case of reversal of I-131 findings from negative to positive after short-term thyroxine withdrawal combined with treatment with recombinant human thyroid-stimulating hormone (rhTSH). MATERIALS AND METHODS: The authors obtained multiple I-131 whole-body scans with 4-week thyroid hormone withdrawal, post-I-131 therapy scans, nonthyroid withdrawal Tl-201 chloride whole-body tumor images, and finally combined 2.5-week thyroid hormone withdrawal and rhTSH-stimulation I-131 whole-body scans before and after therapy. RESULTS: The authors examined one patient during a period of 9 years whose I-131 whole-body scan results were at first positive and then became negative. After a combination of rhTSH stimulation and thyroid hormone withdrawal, the results changed again to I-131 positive. CONCLUSIONS: This is the first known case in which I-131 findings changed from negative to positive. A combination of rhTSH stimulation and nearly adequate withdrawal may help convert more I-131-negative whole-body scans to positive.

Adenocarcinoma, Follicular↗
PubMed2002

Penile implant on bone scan imaging: a case study.

We present an unusual case of the incidental finding of a penile implant on a whole-body bone scan obtained for back pain in a patient with osteoporosis and vertebral body fractures. On 2 separate occasions, this patient underwent 3-h delayed whole-body bone scanning with (99m)Tc-methylene diphosphonate. The images showed acute and then subacute vertebral body fractures. On both imaging occasions, the bone scan that included the region of the implant clearly showed the penis, but visualization was better on the second scan. Penile implants have not been described in the nuclear medicine literature, and it is important to recognize the diagnostic possibilities when penile photopenia is identified.

Aged↗